Search Results - "Wu, Frank S"
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The predictability of serum anti-Müllerian level in IVF/ICSI outcomes for patients of advanced reproductive age
Published in Reproductive biology and endocrinology (15-08-2011)“…The role of serum anti-Müllerian hormone (AMH) as predictor of in-vitro fertilization outcomes has been much debated. The aim of the present study is to…”
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2
Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma
Published in The New England journal of medicine (12-07-2012)“…Treatment with trametinib, a MEK inhibitor, resulted in significantly improved progression-free and overall survival, as compared with chemotherapy, in…”
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DREAMM-8: A Phase III Study of the Efficacy and Safety of Belantamab Mafodotin with Pomalidomide and Dexamethasone (B-Pd) Vs Pomalidomide Plus Bortezomib and Dexamethasone (PVd) in Patients with Relapsed/Refractory Multiple Myeloma (RRMM)
Published in Blood (05-11-2020)“…Introduction: Belantamab mafodotin (belamaf; GSK2857916) is a B-cell maturation antigen (BCMA)-targeting antibody-drug conjugate. In the pivotal Phase II…”
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The impact of endometrioma and laparoscopic cystectomy on serum anti-Müllerian hormone levels
Published in Reproductive biology and endocrinology (09-06-2011)“…Serum anti-Müllerian hormone (AMH) had been proposed as a marker of ovarian reserve. The aim of this study was to evaluate the impact of endometrioma and…”
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Tumor-specific circulating cell-free DNA (cfDNA) to predict clinical outcome in BRAF V600 mutation-positive melanoma patients (pts) treated with the MEK inhibitor trametinib (T) or chemotherapy (C)
Published in Journal of clinical oncology (20-05-2013)“…Abstract only 9020 Background: Tumor-derived cfDNA in the blood is a potential alternative source to derive tumor mutation (mut) status and could be a useful…”
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MEK114653: A randomized, multicenter, phase II study to assess efficacy and safety of trametinib (T) compared with docetaxel (D) in KRAS -mutant advanced non–small cell lung cancer (NSCLC)
Published in Journal of clinical oncology (20-05-2013)“…Abstract only 8029 Background: KRAS mutations are detected in 25% of NSCLC, and there are no approved targeted therapies for this subset of NSCLC. D, an…”
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METRIC phase III study: Efficacy of trametinib (T), a potent and selective MEK inhibitor (MEKi), in progression-free survival (PFS) and overall survival (OS), compared with chemotherapy (C) in patients (pts) with BRAF V600E/K mutant advanced or metastatic melanoma (MM)
Published in Journal of clinical oncology (20-06-2012)“…Abstract only LBA8509 Background: Dacarbazine (D) and paclitaxel (P) have been used to treat MM pts with limited effect. The MM treatment landscape has…”
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METRIC phase III study: Efficacy of trametinib (T), a potent and selective MEK inhibitor (MEKi), in progression-free survival (PFS) and overall survival (OS) compared with chemotherapy (C) in patients (pts) with BRAF V600/k mutant advanced or metastatic melanoma (MM)
Published in Journal of clinical oncology (20-05-2012)“…Abstract only LBA8509 The full, final text of this abstract will be available at abstract.asco.org at 12:01 AM (EDT) on Monday, June 4, 2012, and in the Annual…”
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9
Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma
Published in The New England journal of medicine (2012)Get full text
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