Search Results - "Wu, Fengbo"

A pharmacovigilance study of association between proton pump inhibitor and dementia event based on FDA adverse event reporting system data by Wu, Bin, Hu, Qiaozhi, Tian, Fangyuan, Wu, Fengbo, Li, Yuwen, Xu, Ting

“…Proton pump inhibitor (PPI) was widely used around the world. Studies suggested conflicting results between PPI treatment and dementia event. This study…”
Get full text

Acute Kidney Injury Associated With Remdesivir: A Comprehensive Pharmacovigilance Analysis of COVID-19 Reports in FAERS by Wu, Bin, Luo, Min, Wu, Fengbo, He, Zhiyao, Li, Yuwen, Xu, Ting

“…Acute kidney injury (AKI) is a common complication among patients with the novel coronavirus (COVID-19). COVID-19 along with AKI usually resulted in a poor…”
Get full text

Recent progress on vascular endothelial growth factor receptor inhibitors with dual targeting capabilities for tumor therapy by Liu, Yun, Li, Yang, Wang, Yuxi, Lin, Congcong, Zhang, Dan, Chen, Juncheng, Ouyang, Liang, Wu, Fengbo, Zhang, Jifa, Chen, Lei

“…Abstract Vascular endothelial growth factor receptors (VEGFRs) are a family of receptor protein tyrosine kinases that play an important role in the regulation…”
Get full text

Novel Self-Assembled Micelles Based on Cholesterol-Modified Antimicrobial Peptide (DP7) for Safe and Effective Systemic Administration in Animal Models of Bacterial Infection by Zhang, Rui, Wu, Fengbo, Wu, Lei, Tian, Yaomei, Zhou, Bailing, Zhang, Xueyan, Huang, Rong, Yu, Chaoheng, He, Gu, Yang, Li

“…Owing to their broad-spectrum antibacterial properties, multitarget effects, and low drug resistance, antimicrobial peptides (AMPs) have played critical roles…”
Get full text

Targeted therapies and conventional care for the treatment of ankylosing spondylitis in China: a cost-effectiveness analysis based on the network-meta analysis by Shi, Jiaqi, Zhou, Wenxin, Lin, Tong, Wu, Fengbo, Hu, Ming

“…This study aimed to evaluate the long-term cost-effectiveness of conventional care (CC) and seven first-line targeted therapies marketed in China for the…”
Get full text

Mechanisms of PANoptosis and relevant small-molecule compounds for fighting diseases by Wang, Lian, Zhu, Yanghui, Zhang, Lu, Guo, Linghong, Wang, Xiaoyun, Pan, Zhaoping, Jiang, Xian, Wu, Fengbo, He, Gu

“…Pyroptosis, apoptosis, and necroptosis are mainly programmed cell death (PCD) pathways for host defense and homeostasis. PANoptosis is a newly distinct…”
Get full text

A pharmacovigilance study of chronic kidney disease in diabetes mellitus patients with statin treatment by using the US Food and Drug Administration adverse event reporting system by Zhang, Jingyi, Guo, Yuting, Wei, Chunyan, Yan, Yu, Shan, Huifang, Wu, Bin, Wu, Fengbo

“…Statins were regarded as a main medication for managing hypercholesterolemia. Administration of statin therapy could reduce the incidence of cardiovascular…”
Get full text

Impact of the expert consensus on polypharmacy and potentially inappropriate medication use in elderly lung cancer outpatients with multimorbidity: An interrupted time series analysis, 2016–2021 by Tian, Fangyuan, Chen, Zhaoyan, Tang, Rui, Feng, Qiyi, Wu, Fengbo

“…Objectives: Elderly lung cancer patients often have chronic diseases other than lung cancer. Therefore, this kind of population is often accompanied by…”
Get full text

Narciclasine induces autophagy‐dependent apoptosis in triple‐negative breast cancer cells by regulating the AMPK‐ULK1 axis by Cao, Chuan, Huang, Wei, Zhang, Nan, Wu, Fengbo, Xu, Ting, Pan, Xiaoli, Peng, Cheng, Han, Bo

“…Objectives Autophagy and apoptosis are major types of eukaryotic programmed cell death, and regulating these processes holds promise for treating cancers. In…”
Get full text

Expanding the horizons of targeted protein degradation: A non-small molecule perspective by Huang, Xiaowei, Wu, Fengbo, Ye, Jing, Wang, Lian, Wang, Xiaoyun, Li, Xiang, He, Gu

“…Targeted protein degradation (TPD) represented by proteolysis targeting chimeras (PROTACs) marks a significant stride in drug discovery. A plethora of…”
Get full text

Efficacy and safety of inclisiran in stroke or cerebrovascular disease prevention: a systematic review and meta-analysis of randomized controlled trials by Luo, Min, Liu, Yihan, Xu, Xinyi, Liu, Kai, Shen, Chao, Hu, Haoyang, He, Zhiyao, Wu, Fengbo

“…As the impact of inclisiran in stroke prevention in atherosclerotic cardiovascular disease (ASCVD) patients or those at high risk of ASCVD is still unclear, we…”
Get full text

Nanomedicines for Overcoming Cancer Drug Resistance by Hu, Tingting, Gong, Hanlin, Xu, Jiayue, Huang, Yuan, Wu, Fengbo, He, Zhiyao

“…Clinically, cancer drug resistance to chemotherapy, targeted therapy or immunotherapy remains the main impediment towards curative cancer therapy, which leads…”
Get full text

Cardiovascular safety of febuxostat and allopurinol in patients with gout: A meta-analysis by Guan, Xudong, Zhang, Shengzhao, Liu, Jiayan, Wu, Fengbo, Zhou, Lingyan, Liu, Ying, Su, Na

“…Gout is a common disease and is usually treated with uric acid-lowering drugs (the most commonly used of which are febuxostat and allopurinol). However, the…”
Get full text

Adverse event profiles of drug-induced liver injury caused by antidepressant drugs: a disproportionality analysis by Jiang, Aidou, Wei, Chunyan, Zhu, Weiwei, Wu, Fengbo, Wu, Bin

“…Antidepressants are widely used to manage depression and other psychiatric diseases. A previous study revealed that hepatotoxicity was the main adverse event…”
Get full text

Modified Fe3O4 Magnetic Nanoparticle Delivery of CpG Inhibits Tumor Growth and Spontaneous Pulmonary Metastases to Enhance Immunotherapy by Zhang, Xueyan, Wu, Fengbo, Men, Ke, Huang, Rong, Zhou, Bailin, Zhang, Rui, Zou, Rui, Yang, Li

“…As a novel toll-like receptor 9 (TLR9) agonist, synthetic unmethylated cytosine-phosphate-guanine (CpG) oligodeoxynucleotides can stimulate a Th1 immune…”
Get full text

A Numerical-Experimental Framework to Separate the Effects of Different Turbulence Components on the Buffeting Forces of Bluff-body Structures by Wu, Bo, Zhou, Jianting, Xin, Jingzhou, Zhang, Hong, Wu, Fengbo

“…In conventional buffeting analyses of flexible civil engineering structures, the differences between the effects of longitudinal (u-) and vertical (w-)…”
Get full text

Biomimetic Cell-Derived Nanoparticles: Emerging Platforms for Cancer Immunotherapy by Hu, Tingting, Huang, Yuezhou, Liu, Jing, Shen, Chao, Wu, Fengbo, He, Zhiyao

“…Cancer immunotherapy can significantly prevent tumor growth and metastasis by activating the autoimmune system without destroying normal cells. Although cancer…”
Get full text

Risk of diabetic ketoacidosis of SGLT2 inhibitors in patients with type 2 diabetes: a systematic review and network meta-analysis of randomized controlled trials by Yang, Shiwen, Liu, Ying, Zhang, Shengzhao, Wu, Fengbo, Liu, Dan, Wu, Qingfang, Zheng, Hanrui, Fan, Ping, Su, Na

“…Sodium-glucose cotransporter-2 (SGLT2) inhibitors have proven to be effective in improving glycemic control in patients with type 2 diabetes mellitus (T2DM)…”
Get full text

Long non-coding RNA NEAT1 regulates epithelial membrane protein 2 expression to repress nasopharyngeal carcinoma migration and irradiation-resistance through miR-101-3p as a competing endogenous RNA mechanism by Wang, Yujia, Wang, Chunting, Chen, Can, Wu, Fengbo, Shen, Pengfei, Zhang, Peng, He, Gu, Li, Xiang

“…The altered expression of long non-coding RNAs (lncRNAs) is often related to carcinogenesis, metastasis and resistance to radiation or chemotherapy. In the…”
Get full text

ProNGF/NGF Modulates Autophagy and Apoptosis through PI3K/Akt/mTOR and ERK Signaling Pathways following Cerebral Ischemia-Reperfusion in Rats by Li, Yanbo, Wu, Fengbo, Zhou, Muke, Zhou, Jie, Cui, Shuhui, Guo, Jian, Wu, Junhao, He, Li

“…NGF is involved in the process of autophagy; however, the underlying mechanisms of proNGF/NGF on autophagy in cerebral ischemia-reperfusion (CIR) remain…”
Get full text