Search Results - "Wu, Fenfang"
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Generation of hepatobiliary organoids from human induced pluripotent stem cells
Published in Journal of hepatology (01-06-2019)“…[Display omitted] •We established a system to generate hiPSC-derived hepatobiliary organoids in vitro.•To varying degrees, this model recapitulated several key…”
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Significant association between high neutrophil-lymphocyte ratio and poor prognosis in patients with hepatocellular carcinoma: a systematic review and meta-analysis
Published in Frontiers in immunology (21-09-2023)“…Objective Whether neutrophil-lymphocyte ratio (NLR) is an applicative predictor of poor prognosis in patients with hepatocellular carcinoma (HCC) remains…”
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Untargeted metabolomics reveals sour jujube kernel benefiting the nutritional value and flavor of Morchella esculenta
Published in Open life sciences (31-08-2023)“…Nucleosides, organic acids, and amino acids separated from are well known for their nutritional value and flavor. However, how to increase their content in a…”
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Decelerated genome evolution in modern vertebrates revealed by analysis of multiple lancelet genomes
Published in Nature communications (19-12-2014)“…Vertebrates diverged from other chordates ~500 Myr ago and experienced successful innovations and adaptations, but the genomic basis underlying vertebrate…”
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Efficacy and safety of second-line therapies for advanced hepatocellular carcinoma: a network meta-analysis of randomized controlled trials
Published in BMC cancer (19-08-2024)“…The selection of appropriate second-line therapy for liver cancer after first-line treatment failure poses a significant clinical challenge due to the lack of…”
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Discovery of the chemical constituents, structural characteristics, and pharmacological functions of Chinese caterpillar fungus
Published in Open Chemistry (26-05-2023)“…Caterpillar fungus ( ) has been widely used as a traditional Chinese medicine for several decades. It is essential to clarify the product composition,…”
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Keshan Disease: A Potentially Fatal Endemic Cardiomyopathy in Remote Mountains of China
Published in Frontiers in pediatrics (09-03-2021)“…Keshan disease (KD) as an endemic, highly lethal cardiomyopathy, first reported in northeast China's Keshan County in 1935. The clinical manifestations of…”
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Association of hepatitis C infection and risk of kidney cancer: A systematic review and meta‐analysis of observational studies
Published in Journal of viral hepatitis (01-02-2021)“…Although some epidemiological studies have investigated the association between Hepatitis C virus (HCV) infection and the development of kidney cancer, the…”
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Human Hepatic Cancer Stem Cells (HCSCs) Markers Correlated With Immune Infiltrates Reveal Prognostic Significance of Hepatocellular Carcinoma
Published in Frontiers in genetics (28-02-2020)“…Several markers have been reported to be specific for hepatic cancer stem cells (HCSCs), which is usually thought to be highly associated with poor clinical…”
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Generation of Hepatocytes and Nonparenchymal Cell Codifferentiation System from Human-Induced Pluripotent Stem Cells
Published in Stem cells international (22-11-2022)“…To date, hepatocytes derived from human-induced pluripotent stem cells (hiPSC) provide a potentially unlimited resource for clinical application and drug…”
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The Nuclear DNA Content and Genetic Diversity of Lampetra morii
Published in PloS one (07-07-2016)“…We investigated the nuclear DNA content and genetic diversity of a river lamprey, the Korean lamprey Lampetra morii, which is distributed in the northeast of…”
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Efficacy of extracts from Datura Metel L. for Psoriasis: a meta-analysis of case series and single-arm studies
Published in BMC complementary and alternative medicine (14-09-2023)“…Abstract Background Datura Metel L. has been used to treat psoriasis in China for a long time. The effect of extracts from Datura Metel L. for Psoriasis has…”
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13
Cardiomyocytes induced from hiPSCs by well-defined compounds have therapeutic potential in heart failure by secreting PDGF-BB
Published in Signal transduction and targeted therapy (29-07-2022)“…Recent studies have suggested that transplant of hiPS-CMs is a promising approach for treating heart failure. However, the optimally clinical benefits have…”
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Lamprey variable lymphocyte receptors mediate complement-dependent cytotoxicity
Published in The Journal of immunology (1950) (01-02-2013)“…An alternative adaptive-immune system is present in the most basal vertebrates--lampreys and hagfish--the only surviving jawless vertebrates. These eel-like…”
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Retaining mTeSR1 Medium during Hepatic Differentiation Facilitates Hepatocyte-Like Cell Survival by Decreasing Apoptosis
Published in Cellular physiology and biochemistry (01-01-2018)“…Background/Aims: Hepatocyte-like cells derived from human pluripotent stem cells could be an important cell source for hepatocyte transplantation. The present…”
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Characterization, phylogenetic analysis and cDNA cloning of natterin-like gene from the blood of lamprey, Lampetra japonica
Published in Immunology letters (01-11-2012)“…Highlights ► Cloned the full-length cDNA of natterin-like gene from the blood of Lampetra japonica . ► The first to report the amino acid sequences of…”
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Monoclonal and polyclonal antibodies against the precursor of recombinant human insulin
Published in Acta biochimica et biophysica Sinica (01-08-2013)“…The precursor of recombinant human insulin is also called recombinant proinsulin. It is a fusion protein containing pro tection peptide and insulin. The…”
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Effects of the recombinant toxin protein rLj-RGD3 in multidrug-resistant human breast carcinoma cells
Published in Acta biochimica et biophysica Sinica (01-05-2012)“…We have previously reported that Lj-RGD3, a novel RGD-toxin protein, was isolated from the buccal gland of Lampetra japonica. The recombinant protein rLj-RGD3…”
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Proteomic identification of exosomes derived from psoriasis cells using data-independent acquisition mass spectrometry
Published in Archives of dermatological research (24-05-2024)“…Psoriasis is renowned for its chronic nature and complex pathophysiology, with exosomes playing a crucial regulatory role within it. However, the proteomic…”
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NICIP, an inhibitory molecule for lamprey variable lymphocyte receptor to signal transduction (P1291)
Published in The Journal of immunology (1950) (01-05-2013)“…Abstract Lamprey and hagfish are the most ancient jawless vertebrates, which are serving as a “living fossil” of immunological origin and evolution. NICIP is a…”
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