Search Results - "Wu, Dahua"
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Efficacy and safety of ginkgo biloba extract combined with donepezil hydrochloride in the treatment of Chinese patients with vascular dementia: A systematic review meta-analysis
Published in Frontiers in pharmacology (03-07-2024)“…To conduct a meta-analysis of the effectiveness and safety of ginkgo biloba extract combined with donepezil hydrochloride vs. donepezil for the treatment of…”
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Association between white matter alterations and domain-specific cognitive impairment in cerebral small vessel disease: A meta-analysis of diffusion tensor imaging
Published in Frontiers in aging neuroscience (22-11-2022)“…To investigate the association between diffusion tensor imaging (DTI) findings and domain-specific cognitive impairment in cerebral small vessel disease…”
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Beneficial effects and safety of traditional Chinese medicine for chronic inflammatory demyelinating polyradiculoneuropathy: A case report and literature review
Published in Frontiers in neurology (06-04-2023)“…Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune-mediated neuropathy. First-line treatments for CIDP include corticosteroids,…”
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Association between diffusion tensor imaging findings and domain-specific cognitive impairment in cerebral small vessel disease: a protocol for systematic review and meta-analysis
Published in BMJ open (21-09-2021)“…IntroductionCognitive impairment is the main clinical manifestation of cerebral small vessel disease (CSVD). However, the mechanism and structural damage in…”
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The therapeutic effect and mechanism of Chinese medicine Xuan-Yun-Ding on posterior circulation ischemia with vertigo in a rabbit model
Published in Pakistan journal of pharmaceutical sciences (01-05-2021)“…The aim of research is to unveil the mechanisms of the beneficial effects of XYD on PCIV in a rabbit model. 40 New Zealand white rabbits were randomly divided…”
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Efficacy and safety of naotaifang capsules for hypertensive cerebral small vessel disease: Study protocol for a multicenter, randomized, double-blind, placebo-controlled clinical trial
Published in Frontiers in pharmacology (06-01-2023)“…Hypertensive cerebral small vessel disease (HT-CSVD) is a cerebrovascular clinical, imaging and pathological syndrome caused by hypertension (HT). The…”
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The mechanism of Sangdantongluo granule in treating post-stroke spasticity based on multimodal fMRI combined with TMS: Study protocol
Published in Contemporary clinical trials communications (01-06-2024)“…Post-stroke spasticity (PSS) is among the prevalent complications of stroke, greatly affecting motor function recovery and reducing patients' quality of life…”
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A randomized double-blind controlled study protocol on the efficacy and safety of Sangdantongluo granule in the treatment of post-stroke spasticity
Published in Contemporary clinical trials communications (01-10-2022)“…Stroke is the first leading cause of mortality and disability worldwide, and post-stroke spasticity (PSS) is the common complication of stroke. Sangdantongluo…”
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Neuroprotective Effect of Zishen Huoxue Decoction treatment on Vascular Dementia by activating PINK1/Parkin mediated Mitophagy in the Hippocampal CA1 Region
Published in Journal of ethnopharmacology (30-01-2024)“…Zishen Huoxue Decoction (ZSHXD) is a Traditional Chinese Medicine (TCM) prescription for the treatment of vascular dementia (VD). Although the clinical effects…”
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MiR-140 promotes the progression of intracranial aneurysms by targeting BCL2L2
Published in Neuroreport (14-01-2023)“…To investigate the role of miR-140/BCL2L2 axis on the formation of intracranial aneurysms. The expression of miR-140 in the serum of patients with intracranial…”
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SOS1-IT1 silencing alleviates MPP+-induced neuronal cell injury through regulating the miR-124-3p/PTEN/AKT/mTOR pathway
Published in Journal of clinical neuroscience (01-05-2022)“…•Knockdown of SOS1-IT1 relieves MPP+-induced neuronal cell injury.•MiR-124-3p can be targeted by SOS1-IT1.•PTEN is a target of miR-124-3p. Long non-coding RNA…”
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Mechanisms of fibrinogen trans-activation of the EGFR/Ca2+ signaling axis to regulate mitochondrial transport and energy transfer and inhibit axonal regeneration following cerebral ischemia
Published in Journal of neuropathology and experimental neurology (04-11-2024)“…Ischemic stroke results in inhibition of axonal regeneration but the roles of fibrinogen (Fg) in neuronal signaling and energy crises in experimental stroke…”
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MiR-140 promotes the progression of intracranial aneurysms by targeting BCL2L2
Published in Neuroreport (24-11-2022)“…To investigate the role of miR-140/BCL2L2 axis on the formation of intracranial aneurysms. The expression of miR-140 in the serum of patients with intracranial…”
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Factors associated with relapses in relapsing-remitting multiple sclerosis: A systematic review and meta-analysis
Published in Medicine (Baltimore) (02-07-2020)“…The relapse is character of relapsing-remitting multiple sclerosis. The therapeutic goal is to reduce the risk of relapse. Factors associated with relapses can…”
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Protective effects of Zishen Huoxue recipe against neuronal injury in the neurovascular unit of rats with vascular dementia by interfering with inflammatory cascade-induced pyroptosis
Published in Neuropeptides (Edinburgh) (01-12-2023)“…Chinese herbal formulas show considerable therapeutic benefits in dementia. This study specifically explored the protective action of Zishen Huoxue Recipe on…”
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THSG alleviates cerebral ischemia/reperfusion injury via the GluN2B–CaMKII–ERK1/2 pathway
Published in Phytomedicine (Stuttgart) (01-07-2024)“…The potential therapeutic targeting of PINK1-PARK2-mediated mitophagy against cerebral ischemia/reperfusion (CI/R) injury involves the pathophysiological…”
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Decreased spasticity of Baishaoluoshi Decoction through the BDNF/TrKB-KCC2 pathway on poststroke spasticity rats
Published in Neuroreport (06-10-2021)“…K+-Cl- cotransporter-2 (KCC2), which primarily extrudes chloride in mature neurons, triggers hemiplegia limb spasticity after ischemic stroke by affecting…”
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Decreased spasticity of Baishaoluoshi Decoction through the BDNF/TrKB-KCC2 pathway on poststroke spasticity rats
Published in Neuroreport (19-07-2021)Get full text
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Meta-analysis of the relations between gut microbiota and pathogens and Parkinson's disease
Published in Advances in clinical and experimental medicine : official organ Wroclaw Medical University (01-06-2023)“…The motor symptoms in patients with Parkinson's disease (PD) are commonly preceded by gastrointestinal (GI) symptoms. The enteric nervous system (ENS) has also…”
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Ci antagonizes Hippo signaling in the somatic cells of the ovary to drive germline stem cell differentiation
Published in Cell research (01-10-2015)“…Many stem cell populations are tightly regulated by their local microenvironment (niche), which comprises distinct types of stromal cells. However, little is…”
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