Search Results - "Wu, Cunzao"
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Hepatic stellate cell is activated by microRNA-181b via PTEN/Akt pathway
Published in Molecular and cellular biochemistry (01-01-2015)“…Activation of hepatic stellate cells (HSCs) is an essential event in the initiation and progression of liver fibrosis. MicroRNAs have been shown to play a…”
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Curcumin up‐regulates phosphatase and tensin homologue deleted on chromosome 10 through microRNA‐mediated control of DNA methylation – a novel mechanism suppressing liver fibrosis
Published in The FEBS journal (01-01-2014)“…Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) has been reported to play a role in the suppression of activated hepatic stellate cells…”
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Resveratrol inhibits epithelial-mesenchymal transition and renal fibrosis by antagonizing the hedgehog signaling pathway
Published in Biochemical pharmacology (01-12-2014)“…Epithelial-to-mesenchymal transition (EMT), a biologic process in which tubular cells lose their epithelial phenotypes and acquire new characteristic features…”
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Sophocarpine inhibits tumor progression by antagonizing the PI3K/AKT/mTOR signaling pathway in castration-resistant prostate cancer
Published in PeerJ (San Francisco, CA) (16-09-2022)“…The objective of this study was to investigate the inhibitory effect of sophocarpine on the progression of castration-resistant prostate cancer (CRPC) and the…”
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Epithelial and interstitial Notch1 activity contributes to the myofibroblastic phenotype and fibrosis
Published in Cell communication and signaling (12-11-2019)“…Notch1 signalling is a stem-cell-related pathway that is essential for embryonic development, tissue regeneration and organogenesis. However, the role of…”
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Oxymatrine inhibits the proliferation of prostate cancer cells in vitro and in vivo
Published in Molecular medicine reports (01-06-2015)“…Oxymatrine is an alkaloid, which is derived from the traditional Chinese herb, Sophora flavescens Aiton. Oxymatrine has been shown to exhibit…”
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Preparation, characterization, and in vitro tumor-suppressive effect of anti-miR-21-equipped RNA nanoparticles
Published in Biochemical and biophysical research communications (18-06-2021)“…MicroRNAs play an irreplaceable role in gene expression regulation. Upregulation of several miRNAs increases the risk of invasion and metastasis of breast…”
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Resveratrol suppresses the myofibroblastic phenotype and fibrosis formation in kidneys via proliferation‐related signalling pathways
Published in British journal of pharmacology (01-12-2019)“…Background and Purpose Renal fibrosis acts as the common pathway leading to the development of end‐stage renal disease. Previous studies have shown that…”
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Sedum sarmentosum Bunge extract alleviates inflammation and kidney injury via inhibition of M1-macrophage polarization
Published in Phytomedicine (Stuttgart) (01-09-2019)“…Sedum sarmentosum Bunge extract (SSBE) has been used traditionally to treat liver inflammatory diseases in the Asian area. The aim of this study is to evaluate…”
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Nrf2 inhibits M1 macrophage polarization to ameliorate renal ischemia–reperfusion injury through antagonizing NF-κB signaling
Published in International immunopharmacology (25-12-2024)“…•Nrf2 activity is inhibited during M1 macrophage polarization in vivo and in vitro.•Nrf2 inhibition induces M1 macrophage polarization.•Nrf2 inhibition…”
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[Corrigendum] Anti‑fibrotic effect of Sedum sarmentosum Bunge extract in kidneys via the hedgehog signaling pathway
Published in Molecular medicine reports (01-04-2022)“…Subsequently to the publication of the above paper, an interested reader drew to the authors' attention that certain of the data featured in Fig. 1A on p. 740…”
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Sedum sarmentosum Bunge extract exerts renal anti-fibrotic effects in vivo and in vitro
Published in Life sciences (1973) (06-06-2014)“…Sedum sarmentosum Bunge, a traditional Chinese herbal medicine, has a wide range of clinical effects, including anti-oxidation, anti-inflammation, and…”
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Altered expression of glucose metabolism associated genes in a tacrolimus‑induced post‑transplantation diabetes mellitus in rat model
Published in International journal of molecular medicine (01-10-2019)“…Post‑transplantation diabetes mellitus (PTDM) is a known side effect in transplant recipients administered with immunosuppressant drugs, such as tacrolimus…”
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Anti‑fibrotic effect of Sedum sarmentosum Bunge extract in kidneys via the hedgehog signaling pathway
Published in Molecular medicine reports (01-07-2017)“…Sedum sarmentosum Bunge (SSBE) is a perennial plant widely distributed in Asian countries, and its extract is traditionally used for the treatment of certain…”
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Efficacy and safety of pirarubicin combined with hyaluronic acid for non-muscle invasive bladder cancer after transurethral resection: a prospective, randomized study
Published in International urology and nephrology (01-04-2015)“…Objective To verify the efficacy and safety of intravesical instillation of pirarubicin combined with hyaluronic acid after TURBT in non-muscle invasive…”
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Curcumin up‐regulates phosphatase and tensin homologue deleted on chromosome 10 through micro RNA ‐mediated control of DNA methylation – a novel mechanism suppressing liver fibrosis
Published in The FEBS journal (01-01-2014)“…Phosphatase and tensin homologue deleted on chromosome 10 ( PTEN ) has been reported to play a role in the suppression of activated hepatic stellate cells (…”
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Activation of hepatic stellate cells is suppressed by microRNA-150
Published in International journal of molecular medicine (01-07-2013)“…microRNAs (miRNAs) have recently been reported to be involved in the progression of liver fibrosis. It has previously been shown that miR-150 can inhibit the…”
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Synchronous renal cell carcinoma metastasis to the contralateral adrenal gland and pancreas: A case report with 7-year follow-up subsequent to surgical therapy
Published in Oncology letters (01-06-2016)“…Metastatic renal cell carcinoma (RCC) disseminates to a number of organ sites and few patients demonstrate long-term survival following surgery. However,…”
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