Search Results - "Wu, Congying"
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TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection
Published in Nature communications (10-06-2021)“…TLR4 signaling plays key roles in the innate immune response to microbial infection. Innate immune cells encounter different mechanical cues in both health and…”
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2
Reciprocal regulation of actin filaments and cellular metabolism
Published in European journal of cell biology (01-09-2022)“…For cells to adhere, migrate and proliferate, remodeling of the actin cytoskeleton is required. This process consumes a large amount of ATP while having an…”
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3
An Identification Method for Irregular Components Related to Terminal Blocks in Equipment Cabinet of Power Substation
Published in Sensors (Basel, Switzerland) (01-09-2023)“…Despite the continuous advancement of intelligent power substations, the terminal block components within equipment cabinet inspection work still often require…”
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4
ER-mitochondria contacts promote mtDNA nucleoids active transportation via mitochondrial dynamic tubulation
Published in Nature communications (08-09-2020)“…A human cell contains hundreds to thousands of mitochondrial DNA (mtDNA) packaged into nucleoids. Currently, the segregation and allocation of nucleoids are…”
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5
Eight-lncRNA signature of cervical cancer were identified by integrating DNA methylation, copy number variation and transcriptome data
Published in Journal of translational medicine (08-02-2021)“…Copy number variation (CNV) suggests genetic changes in malignant tumors. Abnormal expressions of long non-coding RNAs (lncRNAs) resulted from genomic and…”
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6
A Method for Matching Information of Substation Secondary Screen Cabinet Terminal Block Based on Artificial Intelligence
Published in Applied sciences (01-03-2024)“…The matching of schematic diagrams and physical information of terminal blocks in substation secondary screen cabinets plays a crucial role in the operation…”
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7
Cirrhotic stiffness affects the migration of hepatocellular carcinoma cells and induces sorafenib resistance through YAP
Published in Journal of cellular physiology (01-03-2019)“…A majority of hepatocellular carcinomas (HCCs) combine with liver cirrhosis. The cirrhotic liver has been implicated in interfering with the effects of…”
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8
Mechanical instability generated by Myosin 19 contributes to mitochondria cristae architecture and OXPHOS
Published in Nature communications (13-05-2022)“…The folded mitochondria inner membrane-cristae is the structural foundation for oxidative phosphorylation (OXPHOS) and energy production. By mechanically…”
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Cortical actin networks induce spatio-temporal confinement of phospholipids in the plasma membrane – a minimally invasive investigation by STED-FCS
Published in Scientific reports (29-06-2015)“…Important discoveries in the last decades have changed our view of the plasma membrane organisation. Specifically, the cortical cytoskeleton has emerged as a…”
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10
Golgi‐associated microtubules are fast cargo tracks and required for persistent cell migration
Published in EMBO reports (04-03-2020)“…Microtubules derived from the Golgi (Golgi MTs) have been implicated to play critical roles in persistent cell migration, but the underlying mechanisms remain…”
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mTORC1 Mediates Biphasic Mechano‐Response to Orchestrate Adhesion‐Dependent Cell Growth and Anoikis Resistance
Published in Advanced science (01-02-2024)“…Cells constantly sense and respond to not only biochemical but also biomechanical changes in their microenvironment, demanding for dynamic metabolic…”
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12
Loss of 4.1N in epithelial ovarian cancer results in EMT and matrix-detached cell death resistance
Published in Protein & cell (01-02-2021)“…Epithelial ovarian cancer (EOC) is one of the leading causes of death from gynecologic cancers and peritoneal dissemination is the major cause of death in…”
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Arp2/3-Branched Actin Maintains an Active Pool of GTP-RhoA and Controls RhoA Abundance
Published in Cells (Basel, Switzerland) (16-10-2019)“…Small GTPases regulate cytoskeletal dynamics, cell motility, and division under precise spatiotemporal control. Different small GTPases exhibit cross talks to…”
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14
RPL23 Links Oncogenic RAS Signaling to p53-Mediated Tumor Suppression
Published in Cancer research (Chicago, Ill.) (01-09-2016)“…The ribosomal protein (RP)-MDM2 interaction is a p53 response pathway critical for preventing oncogenic c-MYC-induced tumorigenesis. To investigate whether the…”
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Apolipoprotein A-1 mimetic peptide 4F promotes endothelial repairing and compromises reendothelialization impaired by oxidized HDL through SR-B1
Published in Redox biology (01-05-2018)“…Disruption of endothelial monolayer integrity is the primary instigating factor for many cardiovascular diseases. High density lipoprotein (HDL) oxidized by…”
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YAP Activation in Promoting Negative Durotaxis and Acral Melanoma Progression
Published in Cells (Basel, Switzerland) (01-11-2022)“…Directed cell migration towards a softer environment is called negative durotaxis. The mechanism and pathological relevance of negative durotaxis in tumor…”
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Deletion of the Arp2/3 complex in megakaryocytes leads to microthrombocytopenia in mice
Published in Blood advances (08-08-2017)“…Actin reorganization regulates key processes in platelet activation. Here we examined the role of the Arp2/3 complex, an essential component in actin filament…”
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18
Multiple SNC-ZCZ Sequence Sets With Optimal Correlations Based on Zak Transforms
Published in IEEE signal processing letters (2024)“…Spectrally-null-constrained (SNC) sequences, characterized by a good zero correlation zone (ZCZ) property, are applied in contemporary communication and radar…”
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New insights into the regulation and cellular functions of the ARP2/3 complex
Published in Nature reviews. Molecular cell biology (01-01-2013)“…The ARP2/3 complex, which nucleates branched actin filament networks, is itself activated by nucleation-promoting factors (NPFs). New understanding is being…”
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20
PPFGED: Federated learning for graphic element detection with privacy preservation in multi-source substation drawings
Published in Expert systems with applications (01-06-2024)“…In digital recognition of substation drawings, a significant challenge is how to accurately detect complex graphic elements in each drawing. Existing detection…”
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