Search Results - "Wu, Chunyong"
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A highly sensitive and selective label-free impedimetric immunosensor for the detection of interleukin-6 based on AuNPs@pDA@NiCo2S4@MoS2 nanocomposite
Published in Mikrochimica acta (1966) (01-12-2024)“…A highly sensitive and selective label-free impedimetric immunosensor based on AuNPs@pDA@NiCo 2 S 4 @MoS 2 nanocomposite modified on the surface of a…”
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A novel sandwich impedimetric immunosensor for detection of apolipoprotein-A1 based on the gold nanoparticle–hybridized mercapto-β-cyclodextrin-Pb(II) metal–organic framework
Published in Mikrochimica acta (1966) (01-01-2023)“…A novel sandwich electrochemical impedimetric immunosensor was proposed to detect apolipoprotein-A1 (Apo-A1), a common biomarker for bladder cancer. The…”
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Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP
Published in British journal of pharmacology (01-07-2012)“…BACKGROUND AND PURPOSE An ATP‐binding cassette (ABC) transporter, breast cancer resistance protein (BCRP)/ABCG2, limits oral bioavailability of sulphasalazine…”
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Age-Related Alterations in Electroencephalography Connectivity and Network Topology During n-Back Working Memory Task
Published in Frontiers in human neuroscience (06-12-2018)“…The study of the healthy brain in elders, especially age-associated alterations in cognition, is important to understand the deficits created by Alzheimer's…”
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Investigating PEGDA and GelMA Microgel Models for Sustained 3D Heterotypic Dermal Papilla and Keratinocyte Co-Cultures
Published in International journal of molecular sciences (21-02-2021)“…Hair follicle morphogenesis is heavily dependent on reciprocal, sequential, and epithelial-mesenchymal interaction (EMI) between epidermal stem cells and the…”
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Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamine
Published in The Journal of pharmacology and experimental therapeutics (01-04-2010)“…This report describes a potent and selective inhibitor of multidrug and toxin extrusion (MATE) protein, pyrimethamine (PYR), and examines its effect on the…”
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Mahuang Decoction Antagonizes Acute Liver Failure via Modulating Tricarboxylic Acid Cycle and Amino Acids Metabolism
Published in Frontiers in pharmacology (29-03-2021)“…Acute liver failure (ALF) is a serious clinical disorder with high fatality rates. Mahuang decoction (MHD), a well-known traditional Chinese medicine, has…”
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Effect of ferrous sulfate fortification in germinated brown rice on seed iron concentration and bioavailability
Published in Food chemistry (01-06-2013)“…► Fe bioavailability from the Fe fortified germinated brown rice was evaluated. ► Germination alone cannot increase the Fe bioavailability in Caco-2 cell. ►…”
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Effect of Zinc Sulfate Fortification in Germinated Brown Rice on Seed Zinc Concentration, Bioavailability, and Seed Germination
Published in Journal of agricultural and food chemistry (22-02-2012)“…Rice is the staple food for more than half of the world’s population and, hence, the main source of a vital micronutrient, zinc (Zn). Unfortunately, the…”
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Pharmacokinetics and metabolomics of the new psychoactive substance 4-chloroethylcathinone
Published in Arabian journal of chemistry (01-09-2023)“…Synthetic 4-Chloroethcathinone (4-CEC) is a derivative of cathinone that belongs to one of the more severe abused substances among new psychoactive substances…”
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Enhancement of Skin Delivery of Drugs Using Proposome Depends on Drug Lipophilicity
Published in Pharmaceutics (13-09-2021)“…The study aims to investigate the propylene glycol-based liposomes named 'proposomes' in enhancing skin permeation of drugs with different physicochemical…”
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Complexity of Wake Electroencephalography Correlates With Slow Wave Activity After Sleep Onset
Published in Frontiers in neuroscience (13-11-2018)“…Sleep electroencephalography (EEG) provides an opportunity to study sleep scientifically, whose chaotic, dynamic, complex, and dissipative nature implies that…”
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Identification of the major metabolites of resveratrol in rat urine by HPLC-MS/MS
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (27-12-2005)“…To identify the major metabolites of resveratrol in rat, rat urine samples were pretreated by using solid-phase extraction technique (SPE) with polyamide…”
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Analysis of the traditional medicine YiGan San by the fragmentation patterns of cadambine indole alkaloids using HPLC coupled with high-resolution MS
Published in Journal of separation science (01-12-2013)“…YiGan San (YGS) has long been used in traditional Japanese and Chinese folk medicine and serves as a potent and novel therapeutic agent to treat Alzheimer's…”
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Critical Role of Hepatic Cyp450s in the Testis-Specific Toxicity of (5R)-5-Hydroxytriptolide in C57BL/6 Mice
Published in Frontiers in pharmacology (21-11-2017)“…Low solubility, tissue accumulation, and toxicity are chief obstacles to developing triptolide derivatives, so a better understanding of the pharmacokinetics…”
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A novel process related impurity and forced degradation study of synthetic wogonin: Development of a liquid chromatographic method for purity control
Published in Journal of pharmaceutical and biomedical analysis (01-12-2012)“…► An unknown process related impurity in synthetic wogonin crude drugs was confirmed as 6-chloro-5,7-dihydroxy-8-methoxy-2-phenyl-4H-chromen-4-one. ► A major…”
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Simultaneous Quantification of Oroxylin A and Its Metabolite Oroxylin A-7-O-Glucuronide: Application to a Pharmacokinetic Study in Rat
Published in Chromatographia (01-07-2011)“…Oroxylin A shows reversal activity on multidrug resistance and has an attractive safety profile. A highly sensitive and specific method based on liquid…”
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SPE and LC for Analysis of the Tissue Distribution of Wogonin and Its Metabolite in Tumor-Bearing Nude Mice
Published in Chromatographia (01-10-2010)“…The tissue distribution of wogonin was investigated for study of its anticancer activity. A robust, reliable, and sensitive LC method was developed for…”
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Drug-delivering-drug approach-based codelivery of paclitaxel and disulfiram for treating multidrug-resistant cancer
Published in International journal of pharmaceutics (25-02-2019)“…[Display omitted] Multidrug resistance (MDR) is a common intractable barrier in success of clinical cancer chemotherapy. Codelivery of two drugs using…”
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High performance liquid chromatography – tandem mass spectrometric determination of cyclovirobuxine D in human plasma
Published in Journal of pharmaceutical and biomedical analysis (11-10-2006)“…A sensitive, specific and rapid high performance liquid chromatography – tandem mass spectrometric (LC/MS/MS) method for the determination of cyclovirobuxine D…”
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