Search Results - "Wu, Chuanjie"

OPLS4: Improving Force Field Accuracy on Challenging Regimes of Chemical Space by Lu, Chao, Wu, Chuanjie, Ghoreishi, Delaram, Chen, Wei, Wang, Lingle, Damm, Wolfgang, Ross, Gregory A, Dahlgren, Markus K, Russell, Ellery, Von Bargen, Christopher D, Abel, Robert, Friesner, Richard A, Harder, Edward D

“…We report on the development and validation of the OPLS4 force field. OPLS4 builds upon our previous work with OPLS3e to improve model accuracy on challenging…”
Get full text

OPLS3e: Extending Force Field Coverage for Drug-Like Small Molecules by Roos, Katarina, Wu, Chuanjie, Damm, Wolfgang, Reboul, Mark, Stevenson, James M, Lu, Chao, Dahlgren, Markus K, Mondal, Sayan, Chen, Wei, Wang, Lingle, Abel, Robert, Friesner, Richard A, Harder, Edward D

“…Building upon the OPLS3 force field we report on an enhanced model, OPLS3e, that further extends its coverage of medicinally relevant chemical space by…”
Get full text

Polarizable Atomic Multipole-Based AMOEBA Force Field for Proteins by Shi, Yue, Xia, Zhen, Zhang, Jiajing, Best, Robert, Wu, Chuanjie, Ponder, Jay W, Ren, Pengyu

“…Development of the AMOEBA (atomic multipole optimized energetics for biomolecular simulation) force field for proteins is presented. The current version…”
Get full text

OPLS3: A Force Field Providing Broad Coverage of Drug-like Small Molecules and Proteins by Harder, Edward, Damm, Wolfgang, Maple, Jon, Wu, Chuanjie, Reboul, Mark, Xiang, Jin Yu, Wang, Lingle, Lupyan, Dmitry, Dahlgren, Markus K, Knight, Jennifer L, Kaus, Joseph W, Cerutti, David S, Krilov, Goran, Jorgensen, William L, Abel, Robert, Friesner, Richard A

“…The parametrization and validation of the OPLS3 force field for small molecules and proteins are reported. Enhancements with respect to the previous version…”
Get full text

Trial of Thrombectomy 6 to 24 Hours after Stroke Due to Basilar-Artery Occlusion by Jovin, Tudor G., Li, Chuanhui, Wu, Longfei, Wu, Chuanjie, Chen, Jian, Jiang, Changchun, Shi, Zhonghua, Gao, Zongen, Song, Cunfeng, Chen, Wenhuo, Peng, Ya, Yao, Chen, Wei, Ming, Li, Tong, Wei, Liping, Xiao, Guodong, Yang, Hua, Ren, Ming, Duan, Jiangang, Liu, Xinfeng, Yang, Qingwu, Liu, Yuxiu, Zhu, Qingfeng, Shi, Wanchao, Zhu, Qiyi, Li, Xiaobo, Guo, Zaiyu, Yang, Qi, Hou, Chengbei, Zhao, Wenbo, Ma, Qingfeng, Zhang, Yunzhou, Jiao, Liqun, Zhang, Hongqi, Liebeskind, David S., Liang, Hui, Jadhav, Ashutosh P., Wen, Changming, Brown, Scott, Zhu, Liangfu, Ye, Huawei, Ribo, Marc, Chang, Mingze, Song, Haiqing, Chen, Jun, Ji, Xunming

“…In a Chinese trial, endovascular thrombectomy at 6 to 24 hours led to more good outcomes than standard care but also to more cerebral hemorrhages…”
Get full text

AMOEBA Polarizable Atomic Multipole Force Field for Nucleic Acids by Zhang, Changsheng, Lu, Chao, Jing, Zhifeng, Wu, Chuanjie, Piquemal, Jean-Philip, Ponder, Jay W, Ren, Pengyu

“…The AMOEBA polarizable atomic multipole force field for nucleic acids is presented. Valence and electrostatic parameters were determined from high-level…”
Get full text

Current Status of the AMOEBA Polarizable Force Field by Ponder, Jay W, Wu, Chuanjie, Ren, Pengyu, Pande, Vijay S, Chodera, John D, Schnieders, Michael J, Haque, Imran, Mobley, David L, Lambrecht, Daniel S, DiStasio, Robert A, Head-Gordon, Martin, Clark, Gary N. I, Johnson, Margaret E, Head-Gordon, Teresa

“…Molecular force fields have been approaching a generational transition over the past several years, moving away from well-established and well-tuned, but…”
Get full text

Low-Dose Tirofiban Treatment Improves Neurological Deterioration Outcome After Intravenous Thrombolysis by Wu, Chuanjie, Sun, Chenghe, Wang, Lijun, Lian, Yajun, Xie, Nanchang, Huang, Shengming, Zhao, Wenbo, Ren, Ming, Wu, Di, Ding, Jianping, Song, Haiqing, Wang, Yuping, Ma, Qingfeng, Ji, Xunming

“…BACKGROUND AND PURPOSE—Early use of antiplatelet drugs within 24 hours after intravenous thrombolysis (IVT) has always been a confusing clinical problem. The…”
Get full text

Two doses of botulinum toxin type A for the treatment of trigeminal neuralgia: observation of therapeutic effect from a randomized, double-blind, placebo-controlled trial by Zhang, Haifeng, Lian, Yajun, Ma, Yunqing, Chen, Yuan, He, Caihong, Xie, Nanchang, Wu, Chuanjie

“…Background In the majority of cases, trigeminal neuralgia (TN) is a unilateral condition with ultra-short stabbing pain located along one or more branches of…”
Get full text

Both left upper lobectomy and left pneumonectomy are risk factors for postoperative stroke by Xie, Nanchang, Meng, Xianghe, Wu, Chuanjie, Lian, Yajun, Wang, Cui, Yu, Mengyan, Li, Yingjiao, Wang, Yali

“…Retrospective studies have found that left upper lobectomy (LUL) may be a new risk factor for stroke, and the potential mechanism is pulmonary vein thrombosis,…”
Get full text

Cerebral venous sinus thrombosis associated with JAK2 V617F mutation-related pre-primary myelofibrosis: a case report and literature review by Song, Jiahao, Huang, Chanzi, Jia, Lina, Wang, Mengqi, Wu, Chuanjie, Ji, Xunming, Song, Haiqing, Meng, Ran, Zhou, Da

“…Cerebral venous sinus thrombosis (CVST) is a rare but potentially life-threatening subtype of stroke. Prompt and appropriate anticoagulation is crucial for…”
Get full text

Selective intra-arterial brain cooling improves long-term outcomes in a non-human primate model of embolic stroke: Efficacy depending on reperfusion status by Wu, Di, Chen, Jian, Hussain, Mohammed, Wu, Longfei, Shi, Jingfei, Wu, Chuanjie, Ma, Yanhui, Zhang, Mo, Yang, Qi, Fu, Yongjuan, Duan, Yunxia, Ma, Cui, Yan, Feng, Zhu, Zixin, He, Xiaoduo, Yao, Tianqi, Song, Ming, Zhi, Xinglong, Wang, Chunxiu, Cai, Lipeng, Li, Chuanhui, Li, Shengli, Zhang, Yongbiao, Ding, Yuchuan, Ji, Xunming

“…Nearly all stroke neuroprotection modalities, including selective intra-arterial cooling (SI-AC), have failed to be translated from bench to bed side…”
Get full text

Improving Long-Term Functional Outcomes of Ischemic Stroke in the Reperfusion Era by Wu, Chuanjie, Chu, Xuehong, Zhu, Zhanwei, Wu, Di, Ji, Xunming

Get full text

Advancing stroke therapy: innovative approaches with stem cell-derived extracellular vesicles by Song, Jiahao, Zhou, Da, Cui, Lili, Wu, Chuanjie, Jia, Lina, Wang, Mengqi, Li, Jingrun, Ya, Jingyuan, Ji, Xunming, Meng, Ran

“…Stroke is a leading cause of mortality and long-term disability globally, with acute ischemic stroke (AIS) being the most common subtype. Despite significant…”
Get full text

Statins for neuroprotection in spontaneous intracerebral haemorrhage (STATIC): protocol for a multicentre, prospective and randomised controlled trial by Gao, Daiquan, Chu, Xuehong, Zhang, Yunzhou, Yan, Heli, Niu, Lijian, Jiang, Xuebin, Bao, Shiying, Ji, Xunming, Wu, Chuanjie

“…IntroductionIntracerebral haemorrhage (ICH) is a neurological emergency with high morbidity and mortality, and current treatment is limited. Emerging evidence…”
Get full text

A case report: new-onset nummular headache after stenting of the middle cerebral artery by Liu, Yuanyuan, Chu, Xuehong, Dong, Xiao, Yu, Erlan, Jia, Xiaole, Wu, Chuanjie, Ji, Xunming

“…Nummular headache (NH) is categorized as a primary headache in the International Classification of Headache Disorders, Third edition (ICHD-3) diagnostic…”
Get full text

Evaluation of peripapillary retinal nerve fiber layer thickness in intracranial atherosclerotic stenosis by Gao, Yuan, Zhang, Xuxiang, Wu, Di, Wu, Chuanjie, Ren, Changhong, Meng, Tingting, Ji, Xunming

“…Abstract Purpose To evaluate the peripapillary retinal nerve fiber layer thickness (pRNFL) in patients with intracranial atherosclerotic stenosis (ICAS)…”
Get full text

Circulating N-Terminal Probrain Natriuretic Peptide Levels in Relation to Ischemic Stroke and Its Subtypes: A Mendelian Randomization Study by Li, Ming, Xu, Yi, Wu, Jiaqi, Wu, Chuanjie, Li, Ang, Ji, Xunming

“…Mendelian randomization was used to evaluate the potential causal association between N-terminal probrain natriuretic peptide (NT-proBNP) and ischemic stroke…”
Get full text

Safety and efficacy of tirofiban in preventing neurological deterioration in acute ischemic stroke (TREND): Protocol for an investigator-initiated, multicenter, prospective, randomized, open-label, masked endpoint trial by Wang, Jing, Li, Sijie, Li, Chuanhui, Wu, Chuanjie, Song, Haiqing, Ma, Qingfeng, Ji, Xunming, Zhao, Wenbo

“…Antithrombotic therapy prevents adverse ischemic events following acute ischemic stroke (AIS). Intravenous tirofiban provides desirable antiplatelet effects,…”
Get full text

Asymptomatic Intracerebral Hemorrhage May Worsen Clinical Outcomes in Acute Ischemic Stroke Patients Undergoing Thrombectomy by Jiang, Fang, Zhao, Wenbo, Wu, Chuanjie, Zhang, Zhen, Li, Chuanhui, Che, Ruiwen, Chen, Jian, Hu, Weiming, Song, Haiqing, Duan, Jiangang, Ji, Xunming

“…Background: Asymptomatic intracerebral hemorrhage (AICH) is a common phenomenon in patients with acute ischemic stroke (AIS) who were treated with endovascular…”
Get full text