Search Results - "Wu, Chengkun"
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ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties
Published in Nucleic acids research (02-07-2021)“…Abstract Because undesirable pharmacokinetics and toxicity of candidate compounds are the main reasons for the failure of drug development, it has been widely…”
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A risk factor attention-based model for cardiovascular disease prediction
Published in BMC bioinformatics (14-10-2022)“…Abstract Background Cardiovascular disease (CVD) is a serious disease that endangers human health and is one of the main causes of death. Therefore, using the…”
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CGINet: graph convolutional network-based model for identifying chemical-gene interaction in an integrated multi-relational graph
Published in BMC bioinformatics (26-11-2020)“…Elucidation of interactive relation between chemicals and genes is of key relevance not only for discovering new drug leads in drug development but also for…”
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SARS-CoV-2 Omicron RBD shows weaker binding affinity than the currently dominant Delta variant to human ACE2
Published in Signal transduction and targeted therapy (05-01-2022)Get full text
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Dependency-based long short term memory network for drug-drug interaction extraction
Published in BMC bioinformatics (28-12-2017)“…Drug-drug interaction extraction (DDI) needs assistance from automated methods to address the explosively increasing biomedical texts. In recent years, deep…”
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Mining a stroke knowledge graph from literature
Published in BMC bioinformatics (29-07-2021)“…Abstract Background Stroke has an acute onset and a high mortality rate, making it one of the most fatal diseases worldwide. Its underlying biology and…”
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Mining microbe–disease interactions from literature via a transfer learning model
Published in BMC bioinformatics (10-09-2021)“…Abstract Background Interactions of microbes and diseases are of great importance for biomedical research. However, large-scale of microbe–disease interactions…”
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Correction to: Mining a stroke knowledge graph from literature
Published in BMC bioinformatics (08-12-2021)Get full text
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Denoise for propeller acoustic signals based on the improved wavelet thresholding algorithm of CEEMDAN
Published in Cogent engineering (31-12-2024)“…AbstractThe primary objective of this study is to address the issue of noise in underwater propeller signals. The motivation for this research arises from the…”
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GTZ: a fast compression and cloud transmission tool optimized for FASTQ files
Published in BMC bioinformatics (28-12-2017)“…The dramatic development of DNA sequencing technology is generating real big data, craving for more storage and bandwidth. To speed up data sharing and bring…”
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Constructing a database for the relations between CNV and human genetic diseases via systematic text mining
Published in BMC bioinformatics (31-12-2018)“…The detection and interpretation of CNVs are of clinical importance in genetic testing. Several databases and web services are already being used by clinical…”
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GT-WGS: an efficient and economic tool for large-scale WGS analyses based on the AWS cloud service
Published in BMC genomics (19-01-2018)“…Whole-genome sequencing (WGS) plays an increasingly important role in clinical practice and public health. Due to the big data size, WGS data analysis is…”
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ParaBTM: A Parallel Processing Framework for Biomedical Text Mining on Supercomputers
Published in Molecules (Basel, Switzerland) (27-04-2018)“…A prevailing way of extracting valuable information from biomedical literature is to apply text mining methods on unstructured texts. However, the massive…”
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An Interface for Biomedical Big Data Processing on the Tianhe-2 Supercomputer
Published in Molecules (Basel, Switzerland) (01-12-2017)“…Big data, cloud computing, and high-performance computing (HPC) are at the verge of convergence. Cloud computing is already playing an active part in big data…”
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Ultrafast Random‐Pyramid Texturing for Efficient Monocrystalline Silicon Solar Cells
Published in Solar RRL (01-07-2022)“…Herein, an ultrafast random‐pyramid texturing process is proposed for monocrystalline silicon (mono‐Si) solar cells by combining metal‐catalyzed chemical…”
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GTX.Digest.VCF: an online NGS data interpretation system based on intelligent gene ranking and large-scale text mining
Published in BMC medical genomics (20-12-2019)“…An important task in the interpretation of sequencing data is to highlight pathogenic genes (or detrimental variants) in the field of Mendelian diseases. It is…”
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PathNER: a tool for systematic identification of biological pathway mentions in the literature
Published in BMC systems biology (16-10-2013)“…Biological pathways are central to many biomedical studies and are frequently discussed in the literature. Several curated databases have been established to…”
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Long Short-Term Memory Network for Development and Simulation of Warfarin Dosing Model Based on Time Series Anticoagulant Data
Published in Frontiers in cardiovascular medicine (11-05-2022)“…Warfarin is an effective treatment for thromboembolic disease but has a narrow therapeutic index, and dosage can differ tremendously among individuals. The…”
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HFN: Heterogeneous feature network for multivariate time series anomaly detection
Published in Information sciences (01-06-2024)“…As the key step of anomaly detection for multivariate time-series (MTS) data, learning the relations among different variables has been explored by many…”
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Abnormal vibration detection of wind turbine based on temporal convolution network and multivariate coefficient of variation
Published in Mechanical systems and signal processing (15-07-2022)“…•High-resolution (1 Hz) SCADA data with both time and frequency domain information being considered.•A framework based on the spectrum-embedded temporal…”
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