Search Results - "Wu, Ava J."

Small Proline-Rich Protein 1B (SPRR1B) Is a Biomarker for Squamous Metaplasia in Dry Eye Disease by Li, Shimin, Nikulina, Karina, DeVoss, Jason, Wu, Ava J, Strauss, Erich C, Anderson, Mark S, McNamara, Nancy A

“…Squamous metaplasia occurs in ocular surface diseases like Sjögren's syndrome (SS). It is a phenotypic change whereby epithelial cells initiate synthesis of…”
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Optimizing Dry Mouth Treatment for Individuals with Sjögren's Syndrome by Wu, Ava J., DDS

“…A hallmark of the oral component of Sjögren's syndrome (SS) is the complaint of dry mouth thought to be secondary to dysfunction of the salivary glands. This…”
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Clinical practice guidelines for oral management of Sjögren disease: Dental caries prevention by Zero, Domenick T, Brennan, Michael T, Daniels, Troy E, Papas, Athena, Stewart, Carol, Pinto, Andres, Al-Hashimi, Ibtisam, Navazesh, Mahvash, Rhodus, Nelson, Sciubba, James, Singh, Mabi, Wu, Ava J, Frantsve-Hawley, Julie, Tracy, Sharon, Fox, Philip C, Ford, Theresa Lawrence, Cohen, Stephen, Vivino, Frederick B, Hammitt, Katherine M

“…Salivary dysfunction in Sjögren disease can lead to serious and costly oral health complications. Clinical practice guidelines for caries prevention in Sjögren…”
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Salivary gland dysfunction: causes, symptoms, treatment by Atkinson, J C, Wu, A J

“…The three most common known causes of salivary gland dysfunction are medication usage, radiation therapy and Sjogren's syndrome. Current therapeutic options to…”
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Tumor Necrosis Factor-α Regulation of CD4+C25+T Cell Levels in NOD Mice by Wu, Ava J., Hua, Hong, Munson, Sibyl H., McDevitt, Hugh O.

“…The mechanism by which tumor necrosis factor-α (TNF) differentially modulates type I diabetes mellitus in the nonobese diabetic (NOD) mouse is not well…”
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Clinical practice guidelines for oral management of Sjögren disease by Zero, Domenick T., DDS, MS, Brennan, Michael T., DDS, MHS, Daniels, Troy E., DDS, MS, Papas, Athena, DMD, PhD, Stewart, Carol, DDS, MS, Pinto, Andres, DMD, MPH, MSCE, Al-Hashimi, Ibtisam, BDS, MS, PhD, Navazesh, Mahvash, DMD, Rhodus, Nelson, DMD, MPH, Sciubba, James, DMD, PhD, Singh, Mabi, DMD, MS, Wu, Ava J., DDS, Frantsve-Hawley, Julie, RDH, PhD, Tracy, Sharon, PhD, Fox, Philip C., DDS, Ford, Theresa Lawrence, MD, Cohen, Stephen, OD, Vivino, Frederick B., MD, MS, Hammitt, Katherine M., MA

“…Abstract Background Salivary dysfunction in Sjögren disease can lead to serious and costly oral health complications. Clinical practice guidelines for caries…”
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The oral component of Sjögren's syndrome: pass the scalpel and check the water by Wu, Ava J

“…The labial salivary gland biopsy is a diagnostic test for the oral component of Sjögren's syndrome (SS) that has been the subject of controversy and…”
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Xerostomia--clinical evaluation and treatment in general practice by Daniels, T E, Wu, A J

“…Xerostomia is a common symptom with various causes that, if ignored, can lead to serious oral consequences. Clinical evaluation of patients complaining of dry…”
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Management of Salivary Hypofunction in Sjögren’s Syndrome by Wu, Ava J.

“…Opinion statement The strategies to increase oral comfort and manage dental decay can be time consuming and stressful for the patient with newly diagnosed…”
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Interferon-gamma induces a decrease in the intracellular calcium pump in a human salivary gland cell line by Meehan, S, Wu, A J, Kang, E C, Sakai, T, Ambudkar, I S

“…Interferon-gamma (IFN-gamma) +/- tumor necrosis factor-alpha (TNF-alpha) induces antiproliferation and intracellular Ca2+ store depletion in a human…”
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A characterization of major salivary gland flow rates in the presence of medications and systemic diseases by Wu, A J, Ship, J A

“…The purpose of this study was to characterize the effects of medications and systemic diseases on major salivary gland flow rates. Unstimulated and 2%…”
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Salivary gland function and aging: a model for studying the interaction of aging and systemic disease by Baum, B J, Ship, J A, Wu, A J

“…This review describes an approach to examining the interaction of aging and systemic disease on a key aspect of oral physiology, salivation. The approach…”
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Polyreactive antigen‐binding B cells are the predominant cell type in the newborn B cell repertoire by Chen, Zhi Jian, Wheeler, C. James, Shi, Wei, Wu, Ava J., Yarboro, Cheryl H., Gallagher, Michael, Notkins, Abner Louis

“…Polyreactive antibodies bind to a variety of different self and non‐self antigens. The B cells that make these antibodies express the polyreactive Ig receptor…”
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Tumor necrosis factor-alpha regulation of CD4+CD25+ T cell levels in NOD mice by Wu, Ava J, Hua, Hong, Munson, Sibyl H, McDevitt, Hugh O

“…The mechanism by which tumor necrosis factor-alpha (TNF) differentially modulates type I diabetes mellitus in the nonobese diabetic (NOD) mouse is not well…”
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Interferon-γ induced cell death in a cultured human salivary gland cell line by Wu, Ava J., Chen, Zhi Jian, Tsokos, Maria, O'Connell, Brian C., Ambudkar, Indu S., Baum, Bruce J.

“…Increased levels of several cytokines, including interferon‐γ (IFN‐γ) and tumor necrosis factor‐α (TNF‐α), have been demonstrated in the salivary gland…”
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Modulation of MMP-2 (gelatinase A) and MMP-9 (gelatinase B) by interferon-γ in a human salivary gland cell line by Wu, Ava J., Lafrenie, Robert M., Park, Chan, Apinhasmit, Wandee, Chen, Zhi Jian, Birkedal-Hansen, Henning, Yamada, Kenneth M., Stetler-Stevenson, William G., Baum, Bruce J.

“…Gelatinases have been shown to be regulated by many cytokines and growth factors, and have been implicated in the pathogenesis of certain autoimmune diseases…”
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Interferon-γ-induced JAK2 and STAT1 signalling in a human salivary gland cell line by Wu, Ava J., Chen, Zhi Jian, Kan, Elaine C., Baum, Bruce J.

“…We have used a human salivary gland cell line (HSG) as a possible in vitro model to evaluate the effects of IFN‐γ on human salivary gland epithelium (Wu et…”
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Effect of tumor necrosis factor-alpha and interferon-gamma on the growth of a human salivary gland cell line by Wu, A J, Kurrasch, R H, Katz, J, Fox, P C, Baum, B J, Atkinson, J C

“…Interferon-gamma (IFN-gamma) is a product of activated T-lymphocytes, and tumor necrosis factor-alpha (TNF-alpha) is a product of both lymphocytes and…”
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Extended stimulated parotid and submandibular secretion in a healthy young and old population by Wu, A J, Baum, B J, Ship, J A

“…Previous morphological studies have shown that both the human parotid and submandibular glands display age-related reductions in the proportion of fluid…”
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Oral disease associated with dry eyes by Kurrasch, R H, Wu, A J, Fox, P C

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