Search Results - "Wu, Alan HB"

Role of liquid chromatography-high-resolution mass spectrometry (LC-HR/MS) in clinical toxicology by Wu, Alan Hb, Gerona, Roy, Armenian, Patil, French, Deborah, Petrie, Matthew, Lynch, Kara L

“…Background. Gas chromatography (GC) and liquid chromatography (LC) coupled with mass spectrometry (MS) are widely used to confirm drug screening results and…”
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Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study by Perera, Minoli A, PharmD, Cavallari, Larisa H, PharmD, Limdi, Nita A, PharmD, Gamazon, Eric R, MS, Konkashbaev, Anuar, MS, Daneshjou, Roxana, BS, Pluzhnikov, Anna, PhD, Crawford, Dana C, PhD, Wang, Jelai, BS, Liu, Nianjun, PhD, Tatonetti, Nicholas, PhD, Bourgeois, Stephane, MS, Takahashi, Harumi, Prof, Bradford, Yukiko, MS, Burkley, Benjamin M, MS, Desnick, Robert J, Prof, Halperin, Jonathan L, Prof, Khalifa, Sherief I, Prof, Langaee, Taimour Y, PhD, Lubitz, Steven A, MD, Nutescu, Edith A, Prof, Oetjens, Matthew, BS, Shahin, Mohamed H, MS, Patel, Shitalben R, MS, Sagreiya, Hersh, MD, Tector, Matthew, PhD, Weck, Karen E, Prof, Rieder, Mark J, PhD, Scott, Stuart A, PhD, Wu, Alan HB, PhD, Burmester, James K, PhD, Wadelius, Mia, MD, Deloukas, Panos, PhD, Wagner, Michael J, PhD, Mushiroda, Taisei, PhD, Kubo, Michiaki, MD, Roden, Dan M, Prof, Cox, Nancy J, Prof, Altman, Russ B, Prof, Klein, Teri E, PhD, Nakamura, Yusuke, Prof, Johnson, Julie A, Prof

“…Summary Background VKORC1 and CYP2C9 are important contributors to warfarin dose variability, but explain less variability for individuals of African descent…”
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Drug metabolizing enzyme activities versus genetic variances for drug of clinical pharmacogenomic relevance by Wu, Alan Hb

“…Enzymes are critically important in the transportation, metabolism, and clearance of most therapeutic drugs used in clinical practice today. Many of these…”
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Development and preliminary clinical validation of a high sensitivity assay for cardiac troponin using a capillary flow (single molecule) fluorescence detector by Wu, Alan H B, Fukushima, Noelle, Puskas, Robert, Todd, John, Goix, Philippe

“…The European Society of Cardiology and the American College of Cardiology (ESC/ACC) have redefined the criteria for the diagnosis of acute myocardial…”
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National Academy of Clinical Biochemistry Standards of Laboratory Practice: Recommendations for the Use of Cardiac Markers in Coronary Artery Diseases by Wu, Alan H.B, Apple, Fred S, Gibler, W. Brian, Jesse, Robert L, Warshaw, Myron M, Valdes, Roland, Jr

“…The Sixth Conference on the "Standards of Laboratory Practice Series", sponsored by the National Academy of Clinical Biochemistry (NACB), was held on August…”
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Use of genetic and nongenetic factors in warfarin dosing algorithms by Wu, Alan H B

“…Despite the fact that warfarin has been used as an anticoagulant for many years, the safety profile for this drug has been poor. Inappropriate dosing continues…”
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A 23‐Gene Classifier urine test for prostate cancer prognosis by Guo, Jinan, Johnson, Heather, Zhang, Xuhui, Feng, Xiaoyan, Zhang, Heqiu, Simoulis, Athanasios, Wu, Alan HB, Xia, Taolin, Li, Fei, Tan, Wanlong, Johnson, Allan, Dizeyi, Nishtman, Abrahamsson, Per‐Anders, Kenner, Lukas, Chen, Lingwu, Zhong, Wanmei, Xiao, Kefeng, Persson, Jenny L., Zou, Chang

“…The patients were divided into two risk groups based on diagnosis by the 23-Gene Classifier and Kaplan-Meier survival analysis showed statistically significant…”
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Gene expression profiles help identify the tissue of origin for metastatic brain cancers by Wu, Alan H B, Drees, Julia C, Wang, Hangpin, VandenBerg, Scott R, Lal, Anita, Henner, William D, Pillai, Raji

“…Metastatic brain cancers are the most common intracranial tumor and occur in about 15% of all cancer patients. In up to 10% of these patients, the primary…”
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Pharmacogenetic testing affects choice of therapy among women considering tamoxifen treatment by Lorizio, Wendy, Rugo, Hope, Beattie, Mary S, Tchu, Simone, Melese, Teri, Melisko, Michelle, Wu, Alan Hb, Lawrence, H Jeffrey, Nikoloff, Michele, Ziv, Elad

“…Pharmacogenetic testing holds major promise in allowing physicians to tailor therapy to patients based on genotype. However, there is little data on the impact…”
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Race and Genetic Ancestry in Medicine — A Time for Reckoning with Racism by Borrell, Luisa N, Elhawary, Jennifer R, Fuentes-Afflick, Elena, Witonsky, Jonathan, Bhakta, Nirav, Wu, Alan H.B, Bibbins-Domingo, Kirsten, Rodríguez-Santana, José R, Lenoir, Michael A, Gavin, James R, Kittles, Rick A, Zaitlen, Noah A, Wilkes, David S, Powe, Neil R, Ziv, Elad, Burchard, Esteban G

“…U.S. health inequities won’t be eliminated by abandoning the use of race and ethnicity in research and clinical practice, since these variables capture key…”
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Mid-region pro-hormone markers for diagnosis and prognosis in acute dyspnea: results from the BACH (Biomarkers in Acute Heart Failure) trial by Maisel, Alan, Mueller, Christian, Nowak, Richard, Peacock, W Frank, Landsberg, Judd W, Ponikowski, Piotr, Mockel, Martin, Hogan, Christopher, Wu, Alan H B, Richards, Mark, Clopton, Paul, Filippatos, Gerasimos S, Di Somma, Salvatore, Anand, Inder, Ng, Leong, Daniels, Lori B, Neath, Sean-Xavier, Christenson, Robert, Potocki, Mihael, McCord, James, Terracciano, Garret, Kremastinos, Dimitrios, Hartmann, Oliver, von Haehling, Stephan, Bergmann, Andreas, Morgenthaler, Nils G, Anker, Stefan D

“…Our purpose was to assess the diagnostic utility of mid-regional pro-atrial natriuretic peptide (MR-proANP) for the diagnosis of acute heart failure (AHF) and…”
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Biological variation of galectin-3 and soluble ST2 for chronic heart failure: Implication on interpretation of test results by Wu, Alan H.B., PhD, DABCC, Wians, Frank, PhD, DABCC, Jaffe, Allan, MD

“…Background Galectin-3 and soluble ST2 (sST2) are novel serum biomarkers of chronic heart failure. Methods and Results The biological variability of galectin-3…”
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Cardiac Troponin and Outcome in Acute Heart Failure by Peacock, W. Frank, De Marco, Teresa, Fonarow, Gregg C, Diercks, Deborah, Wynne, Janet, Apple, Fred S, Wu, Alan H.B

“…In this large, retrospective registry study, patients hospitalized with acute decompensated heart failure who had elevated cardiac troponin levels had higher…”
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Impact of polysubstance use on high-sensitivity cardiac troponin I over time in homeless and unstably housed women by Riley, Elise D., Vittinghoff, Eric, Wu, Alan H.B., Coffin, Phillip O., Hsue, Priscilla Y., Kazi, Dhruv S., Wade, Amanda, Braun, Carl, Lynch, Kara L.

“…•Cocaethylene and fentanyl are associated with higher levels of hsTnI in poly-drug using women.•Counseling to avoid using cocaine and alcohol in the same two…”
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Chronic alcohol use does not protect against COVID-19 infection by Lebin, Jacob A., Mudan, Anita, Wu, Alan H.B.

“…Since the beginning of the coronavirus pandemic, there has been a concurrent global rise in misinformation about the prevention and treatment of coronavirus…”
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Interpreting Laboratory Results in Transgender Patients on Hormone Therapy by Roberts, Tiffany K., PhD, Kraft, Colleen S., MD, French, Deborah, PhD, Ji, Wuyang, Wu, Alan H.B., PhD, Tangpricha, Vin, MD, PhD, Fantz, Corinne R., PhD

“…Abstract Background Clinical guidelines recommend laboratory monitoring of transgender persons on cross-sex hormone therapy, but gender-specific reference…”
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Circulating Brain-Derived Neurotrophic Factor Has Diagnostic and Prognostic Value in Traumatic Brain Injury by Korley, Frederick K, Diaz-Arrastia, Ramon, Wu, Alan H B, Yue, John K, Manley, Geoffrey T, Sair, Haris I, Van Eyk, Jennifer, Everett, Allen D, Okonkwo, David O, Valadka, Alex B, Gordon, Wayne A, Maas, Andrew I R, Mukherjee, Pratik, Yuh, Esther L, Lingsma, Hester F, Puccio, Ava M, Schnyer, David M

“…Brain-derived neurotrophic factor (BDNF) is important for neuronal survival and regeneration. We investigated the diagnostic and prognostic values of serum…”
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Comparison of Information-Dependent Acquisition on a Tandem Quadrupole TOF vs a Triple Quadrupole Linear Ion Trap Mass Spectrometer for Broad-Spectrum Drug Screening by Thoren, Katie L, Colby, Jennifer M, Shugarts, Sarah B, Wu, Alan H B, Lynch, Kara L

“…Liquid chromatography high-resolution mass spectrometry (LC-HRMS) with untargeted data collection is especially attractive for general unknown drug screening…”
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Measurement of the interleukin family member ST2 in patients with acute dyspnea : Results from the PRIDE (pro-brain natriuretic peptide investigation of dyspnea in the emergency department) study by JANUZZI, James L, PEACOCK, W. Frank, LEWANDROWSKI, Kent B, LLOYD-JONES, Donald M, WU, Alan H. B, MAISEL, Alan S, CHAE, Claudia U, JESSE, Robert L, BAGGISH, Aaron L, O'DONOGHUE, Michelle, SAKHUJA, Rahul, CHEN, Annabel A, VAN KIMMENADE, Roland R. J

“…The aim of this study was to examine the value of measurement of the interleukin-1 receptor family member ST2 in patients with dyspnea. Concentrations of ST2…”
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The biological variation of plasma proenkephalin: data from a stable heart failure cohort by Wu, Alan H B, Anand, Inder

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