Search Results - "Writer, Michele J."

Lipid peptide nanocomplexes for gene delivery and magnetic resonance imaging in the brain by Writer, Michele J., Kyrtatos, Panagiotis G., Bienemann, Alison S., Pugh, John A., Lowe, Andrew S., Villegas-Llerena, Claudio, Kenny, Gavin D., White, Edward A., Gill, Steven S., McLeod, Cameron W., Lythgoe, Mark F., Hart, Stephen L.

“…Gadolinium-labelled nanocomplexes offer prospects for the development of real-time, non-invasive imaging strategies to visualise the location of gene delivery…”
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A Receptor-targeted Nanocomplex Vector System Optimized for Respiratory Gene Transfer by Tagalakis, Aristides D, McAnulty, Robin J, Devaney, James, Bottoms, Stephen E, Wong, John B, Elbs, Martin, Writer, Michele J, Hailes, Helen C, Tabor, Alethea B, O'Callaghan, Christopher, Jaffe, Adam, Hart, Stephen L

“…Synthetic vectors for cystic fibrosis (CF) gene therapy are required that efficiently and safely transfect airway epithelial cells, rather than alveolar…”
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Biophysical Characterization of an Integrin-Targeted Lipopolyplex Gene Delivery Vector by Mohd Mustapa, M. Firouz, Bell, Paul C, Hurley, Christopher A, Nicol, Alastair, Guénin, Erwann, Sarkar, Supti, Writer, Michele J, Barker, Susie E, Wong, John B, Pilkington-Miksa, Michael A, Papahadjopoulos-Sternberg, Brigitte, Ayazi Shamlou, Parviz, Hailes, Helen C, Hart, Stephen L, Zicha, Daniel, Tabor, Alethea B

“…Nonviral gene delivery vectors now show good therapeutic potential:  however, detailed characterization of the composition and macromolecular organization of…”
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Targeting Lipopolyplexes Using Bifunctional Peptides Incorporating Hydrophobic Spacer Amino Acids: Synthesis, Transfection, and Biophysical Studies by Pilkington-Miksa, Michael A, Writer, Michele J, Sarkar, Supti, Meng, Qing-Hai, Barker, Suzie E, Shamlou, Parviz Ayazi, Hailes, Helen C, Hart, Stephen L, Tabor, Alethea B

“…We have developed efficient synthetic routes to two hydrophobic amino acids, suitably protected for solid-phase peptide synthesis, and have successfully…”
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Targeted Gene Delivery to Human Airway Epithelial Cells with Synthetic Vectors Incorporating Novel Targeting Peptides Selected by Phage Display by Writer, Michele J., Marshall, Barry, Pilkington-Miksa, Michael A., Barker, Susie E., Jacobsen, Marianne, Kritz, Angelika, Bell, Paul C., Lester, Douglas H., Tabor, Alethea B., Hailes, Helen C., Klein, Nigel, Hart, Stephen L.

“…Human airway epithelial cell targeting peptides were identified by biopanning on 1HAEo-cells, a well characterised epithelial cell line. Bound phage were…”
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696. Development of Lipid/Peptide (Lip/Tide) Vectors for Respiratory Gene Transfer by Hart, Stephen L., Tagalakis, Aris, Writer, Michele J., Devaney, James, Hailes, Helen C., Tabor, Alethea B., Wong, John B., Bottoms, Steve, McAnulty, Robin J., Scheule, Ron, Cheng, Seng, Jaffe, Adam

“…We are developing synthetic,targeted vector systems for the respiratory system to treat diseases such as cystic fibrosis (CF). Lip/Tide-I vectors comprised an…”
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Synthesis of Bifunctional Integrin-Binding Peptides Containing PEG Spacers of Defined Length for Non-Viral Gene Delivery by Pilkington-Miksa, Michael A., Sarkar, Supti, Writer, Michele J., Barker, Susie E., Shamlou, Parviz Ayazi, Hart, Stephen L., Hailes, Helen C., Tabor, Alethea B.

“…Improving the buffer and serum stability of non‐viral gene delivery vectors, and increasing their circulation time in vivo, is an important focus of current…”
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Targeted gene delivery to human airway epithelial cells with synthetic vectors incorporating novel targeting peptides selected by phage display: Novel Approaches in Nucleic Acid Delivery by WRITER, Michele J, MARSHALL, Barry, KLEIN, Nigel, HART, Stephen L, PILKINGTON-MIKSA, Michael A, BARKER, Susie E, JACOBSEN, Marianne, KRITZ, Angelika, BELL, Paul C, LESTER, Douglas H, TABOR, Alethea B, HAILES, Helen C

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