Search Results - "Wright, Sukhvir K."

In vivo Mechanisms of Antibody-Mediated Neurological Disorders: Animal Models and Potential Implications by Giannoccaro, Maria Pia, Wright, Sukhvir K, Vincent, Angela

“…Over the last two decades, the discovery of antibodies directed against neuronal surface antigens (NSA-Abs) in patients with different forms of encephalitis…”
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NORSE/FIRES: how can we advance our understanding of this devastating condition? by Champsas, Dimitrios, Zhang, Xushuo, Rosch, Richard, Ioannidou, Evangelia, Gilmour, Kimberly, Cooray, Gerald, Woodhall, Gavin, Pujar, Suresh, Kaliakatsos, Marios, Wright, Sukhvir K

“…New onset refractory status epilepticus (NORSE) is a rare and devastating condition characterised by the sudden onset of refractory status epilepticus (RSE)…”
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Multimodal electrophysiological analyses reveal that reduced synaptic excitatory neurotransmission underlies seizures in a model of NMDAR antibody-mediated encephalitis by Wright, Sukhvir K., Rosch, Richard E., Wilson, Max A., Upadhya, Manoj A., Dhangar, Divya R., Clarke-Bland, Charlie, Wahid, Tamara T., Barman, Sumanta, Goebels, Norbert, Kreye, Jakob, Prüss, Harald, Jacobson, Leslie, Bassett, Danielle S., Vincent, Angela, Greenhill, Stuart D., Woodhall, Gavin L.

“…Seizures are a prominent feature in N-Methyl-D-Aspartate receptor antibody (NMDAR antibody) encephalitis, a distinct neuro-immunological disorder in which…”
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Pathogenic antibodies to AQP4: Neuromyelitis optica spectrum disorder (NMOSD) by Wright, Sukhvir K, Wassmer, Evangeline, Vincent, Angela

“…NMOSD is a rare but severe relapsing remitting demyelinating disease that affects both adults and children. Most patients have pathogenic antibodies that…”
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Abolishing spontaneous epileptiform activity in human brain tissue through AMPA receptor inhibition by Wright, Sukhvir K., Wilson, Max A., Walsh, Richard, Lo, William B., Mundil, Nilesh, Agrawal, Shakti, Philip, Sunny, Seri, Stefano, Greenhill, Stuart D., Woodhall, Gavin L.

“…Objective The amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor (AMPAR) is increasingly recognized as a therapeutic target in drug‐refractory…”
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Peripherally-derived LGI1-reactive monoclonal antibodies cause epileptic seizures in vivo by Upadhya, Manoj, Kirmann, Toni, Wilson, Max A, Simon, Christian M, Dhangar, Divya, Geis, Christian, Williams, Robyn, Woodhall, Gavin, Hallermann, Stefan, Irani, Sarosh R, Wright, Sukhvir K

“…One striking clinical hallmark in patients with autoantibodies to leucine-rich glioma inactivated 1 (LGI1) is the very frequent focal seizure semiologies,…”
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Neurodevelopmental outcomes in paediatric immune-mediated and autoimmune epileptic encephalopathy by Wright, Sukhvir K., Wood, Amanda G.

“…Recognition of paediatric autoimmune/immune-mediated encephalitis and epileptic encephalopathy (e.g. NMDAR-Ab encephalitis) has rapidly increased over the last…”
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Encephalitis patient-derived monoclonal GABAA receptor antibodies cause epileptic seizures by Kreye, Jakob, Wright, Sukhvir K, van Casteren, Adriana, Stöffler, Laura, Machule, Marie-Luise, Reincke, S Momsen, Nikolaus, Marc, van Hoof, Scott, Sanchez-Sendin, Elisa, Homeyer, Marie A, Cordero Gómez, César, Kornau, Hans-Christian, Schmitz, Dietmar, Kaindl, Angela M, Boehm-Sturm, Philipp, Mueller, Susanne, Wilson, Max A, Upadhya, Manoj A, Dhangar, Divya R, Greenhill, Stuart, Woodhall, Gavin, Turko, Paul, Vida, Imre, Garner, Craig C, Wickel, Jonathan, Geis, Christian, Fukata, Yuko, Fukata, Masaki, Prüss, Harald

“…Autoantibodies targeting the GABAA receptor (GABAAR) hallmark an autoimmune encephalitis presenting with frequent seizures and psychomotor abnormalities. Their…”
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Human cerebrospinal fluid monoclonal CASPR2 autoantibodies induce changes in electrophysiology, functional MRI, and behavior in rodent models by van Hoof, Scott, Kreye, Jakob, Cordero-Gómez, César, Hoffmann, Julius, Momsen Reincke, S., Sánchez-Sendin, Elisa, Duong, Sophie L., Upadhya, Manoj, Dhangar, Divya, Michór, Paulina, Woodhall, Gavin L., Küpper, Maraike, Oder, Andreas, Kuchling, Joseph, Koch, Stefan Paul, Mueller, Susanne, Boehm-Sturm, Philipp, von Kries, Jens Peter, Finke, Carsten, Kirschstein, Timo, Wright, Sukhvir K., Prüss, Harald

“…•The isolated anti-CASPR2 antibodies all selectively bind the discoidin domain.•Monoclonal anti-CASPR2 antibodies block the interaction of CASPR2 with…”
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Examining cognition and brain networks using magnetoencephalography in paediatric autoimmune encephalitis and acute disseminated encephalomyelitis: a preliminary study by Billaud, Charly H A, Wood, Amanda G, Griffiths-King, Daniel, Kessler, Klaus, Wassmer, Evangeline, Foley, Elaine, Wright, Sukhvir K

“…Abstract Paediatric autoimmune encephalitis, including acute disseminated encephalomyelitis, are inflammatory brain diseases presenting with cognitive…”
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