Search Results - "Wright, S A"

Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota by Luis, Ana S, Baslé, Arnaud, Byrne, Dominic P., Wright, Gareth S. A., London, James A., Jin, Chunsheng, Karlsson, Niclas G., Hansson, Gunnar C., Eyers, Patrick A., Czjzek, Mirjam, Barbeyron, Tristan, Yates, Edwin A., Martens, Eric C., Cartmell, Alan

“…Sulfated glycans are ubiquitous nutrient sources for microbial communities that have coevolved with eukaryotic hosts. Bacteria metabolize sulfated glycans by…”
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Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS by Sala, Fernanda A, Wright, Gareth S A, Antonyuk, Svetlana V, Garratt, Richard C, Hasnain, S Samar

“…Superoxide dismutase-1 (SOD1) maturation comprises a string of posttranslational modifications which transform the nascent peptide into a stable and active…”
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Searching for Genes Responsible for Patulin Degradation in a Biocontrol Yeast Provides Insight into the Basis for Resistance to This Mycotoxin by LANIRI, G, IDNURM, A, WRIGHT, S. A. I, DURAN-PATRON, R, MANNINA, L, FERRACANE, R, RITIENI, A, CASTORIA, R

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Identification of d-arabinan-degrading enzymes in mycobacteria by Al-Jourani, Omar, Benedict, Samuel T., Ross, Jennifer, Layton, Abigail J., van der Peet, Phillip, Marando, Victoria M., Bailey, Nicholas P., Heunis, Tiaan, Manion, Joseph, Mensitieri, Francesca, Franklin, Aaron, Abellon-Ruiz, Javier, Oram, Sophia L., Parsons, Lauren, Cartmell, Alan, Wright, Gareth S. A., Baslé, Arnaud, Trost, Matthias, Henrissat, Bernard, Munoz-Munoz, Jose, Hirt, Robert P., Kiessling, Laura L., Lovering, Andrew L., Williams, Spencer J., Lowe, Elisabeth C., Moynihan, Patrick J.

“…Bacterial cell growth and division require the coordinated action of enzymes that synthesize and degrade cell wall polymers. Here, we identify enzymes that…”
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Unexpected Roles of a Tether Harboring a Tyrosine Gatekeeper Residue in Modular Nitrite Reductase Catalysis by Hedison, Tobias M, Shenoy, Rajesh T, Iorgu, Andreea I, Heyes, Derren J, Fisher, Karl, Wright, Gareth S. A, Hay, Sam, Eady, Robert R, Antonyuk, Svetlana V, Hasnain, S. Samar, Scrutton, Nigel S

“…It is generally assumed that tethering enhances rates of electron harvesting and delivery to active sites in multidomain enzymes by proximity and sampling…”
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Variable Infrared Emission from the Supermassive Black Hole at the Center of the Milky Way by Ghez, A. M, Wright, S. A, Matthews, K, Thompson, D, Le Mignant, D, Tanner, A, Hornstein, S. D, Morris, M, Becklin, E. E, Soifer, B. T

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Long-term outcomes confirm the superior efficacy of extended Heller myotomy with toupet fundoplication for achalasia by WRIGHT, A. S, WILLIAMS, C. W, PELLEGRINI, C. A, OELSCHLAGER, B. K

“…The standard Heller myotomy (SM) for achalasia extends 1 to 2 cm on to the stomach. The authors perform an extended myotomy (EM) (>3 cm) with the goal of…”
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The biophysics of superoxide dismutase-1 and amyotrophic lateral sclerosis by Wright, Gareth S A, Antonyuk, Svetlana V, Hasnain, S Samar

“…Few proteins have come under such intense scrutiny as superoxide dismutase-1 (SOD1). For almost a century, scientists have dissected its form, function and…”
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Disks in the Arches Cluster—Survival in a Starburst Environment by Stolte, A, Morris, M. R, Ghez, A. M, Do, T, Lu, J. R, Wright, S. A, Ballard, C, Mills, E, Matthews, K

“…Deep Keck/NIRC2 HK'L' observations of the Arches cluster near the Galactic center reveal a significant population of near-infrared excess sources. We combine…”
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Enhancement of undergraduate rheumatology teaching through the use of musculoskeletal ultrasound by Wright, S. A., Bell, A. L.

“…Objectives. Musculoskeletal ultrasound (MSUS) is increasingly being used by rheumatologists in routine clinical practice to aid with diagnosis and therapy…”
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Impact of Field Densities of the Naturalized Defoliator Caloptilia triadicae (Lepidoptera: Gracillariidae) on the Invasive Weed Chinese Tallowtree by Wheeler, G. S, Hight, S. D, Wright, S. A

“…Chinese tallowtree, Triadica sebifera (L.) Small (Euphoriaceae), is one of the most aggressive weeds of coastal wetlands and forests of the southeastern United…”
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The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation by Capper, Michael J., Wright, Gareth S. A., Barbieri, Letizia, Luchinat, Enrico, Mercatelli, Eleonora, McAlary, Luke, Yerbury, Justin J., O’Neill, Paul M., Antonyuk, Svetlana V., Banci, Lucia, Hasnain, S. Samar

“…Superoxide dismutase-1 (SOD1) mutants, including those with unaltered enzymatic activity, are known to cause amyotrophic lateral sclerosis (ALS). Several…”
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A randomised interventional trial of omega-3-polyunsaturated fatty acids on endothelial function and disease activity in systemic lupus erythematosus by Wright, S A, O'Prey, F M, McHenry, M T, Leahey, W J, Devine, A B, Duffy, E M, Johnston, D G, Finch, M B, Bell, A L, McVeigh, G E

“…To determine the clinical effect of dietary supplementation with low-dose omega-3-polyunsaturated fatty acids on disease activity and endothelial function in…”
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Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy by Chantadul, Varunya, Wright, Gareth S. A., Amporndanai, Kangsa, Shahid, Munazza, Antonyuk, Svetlana V., Washbourn, Gina, Rogers, Michael, Roberts, Natalie, Pye, Matthew, O’Neill, Paul M., Hasnain, S. Samar

“…Mutations to the gene encoding superoxide dismutase-1 (SOD1) were the first genetic elements discovered that cause motor neuron disease (MND). These mutations…”
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Seasonal Abundance of the Adventive Chinese Tallowtree Herbivore Caloptilia triadicae (Lepidoptera: Gracillariidae) and Its Parasitoids by Wheeler, G. S, Dyer, K, Hight, S. D, Wright, S. A

“…Chinese tallowtree, Triadica sebifera (L.) Small (Malpighiales: Euphorbiaceae), is an invasive weed from southern China that is invasive in the Gulf states of…”
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Modulation of LAT1 (SLC7A5) transporter activity and stability by membrane cholesterol by Dickens, David, Chiduza, George N., Wright, Gareth S. A., Pirmohamed, Munir, Antonyuk, Svetlana V., Hasnain, S. Samar

“…LAT1 (SLC7A5) is a transporter for both the uptake of large neutral amino acids and a number of pharmaceutical drugs. It is expressed in numerous cell types…”
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Crystal Structure of the Japanese Encephalitis Virus Capsid Protein by Poonsiri, Thanalai, Wright, Gareth S A, Solomon, Tom, Antonyuk, Svetlana V

“…Japanese encephalitis (JE) is inflammation and swelling of the brain caused by the JE virus (JEV), a mosquito-borne member of the Flavivirus family. There are…”
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The structural plasticity of the human copper chaperone for SOD1: insights from combined size-exclusion chromatographic and solution X-ray scattering studies by Wright, Gareth S A, Hasnain, S Samar, Grossmann, J Günter

“…The incorporation of copper into biological macromolecules such as SOD1 (Cu,Zn superoxide dismutase) is essential for the viability of most organisms. However,…”
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Disease causing mutants of TDP-43 nucleic acid binding domains are resistant to aggregation and have increased stability and half-life by Austin, James A., Wright, Gareth S. A., Watanabe, Seiji, Grossmann, Günter, Antonyuk, Svetlana V., Yamanaka, Koji, Hasnain, S. Samar

“…Over the last two decades many secrets of the age-related human neural proteinopathies have been revealed. A common feature of these diseases is abnormal, and…”
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LAT1 (SLC7A5) and CD98hc (SLC3A2) complex dynamics revealed by single‐particle cryo‐EM by Chiduza, George N., Johnson, Rachel M., Wright, Gareth S. A., Antonyuk, Svetlana V., Muench, Stephen P., Hasnain, S. Samar

“…Solute carriers are a large class of transporters that play key roles in normal and disease physiology. Among the solute carriers, heteromeric amino‐acid…”
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