Search Results - "Wright, Katherine N"

The tubular striatum and nucleus accumbens distinctly represent reward-taking and reward-seeking by Wright, Katherine N, Wesson, Daniel W

“…The ventral striatum regulates motivated behaviors that are essential for survival. The ventral striatum contains both the nucleus accumbens (NAc), which is…”
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Neurochemical organization of the ventral striatum’s olfactory tubercle by Cansler, Hillary L., Wright, Katherine N., Stetzik, Lucas A., Wesson, Daniel W.

“…The ventral striatum is a collection of brain structures, including the nucleus accumbens, ventral pallidum and the olfactory tubercle (OT). While much…”
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Ventral striatal islands of Calleja neurons control grooming in mice by Zhang, Yun-Feng, Vargas Cifuentes, Luigim, Wright, Katherine N., Bhattarai, Janardhan P., Mohrhardt, Julia, Fleck, David, Janke, Emma, Jiang, Chunjie, Cranfill, Suna L., Goldstein, Nitsan, Schreck, Mary, Moberly, Andrew H., Yu, Yiqun, Arenkiel, Benjamin R., Betley, J. Nicholas, Luo, Wenqin, Stegmaier, Johannes, Wesson, Daniel W., Spehr, Marc, Fuccillo, Marc V., Ma, Minghong

“…The striatum comprises multiple subdivisions and neural circuits that differentially control motor output. The islands of Calleja (IC) contain clusters of…”
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Repeated Ketamine Exposure Induces an Enduring Resilient Phenotype in Adolescent and Adult Rats by Parise, Eric M, Alcantara, Lyonna F, Warren, Brandon L, Wright, Katherine N, Hadad, Roey, Sial, Omar K, Kroeck, Kyle G, Iñiguez, Sergio D, Bolaños-Guzmán, Carlos A

“…Background Major depressive disorder afflicts up to 10% of adolescents. However, nearly 50% of those afflicted are considered nonresponsive to available…”
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Viral-mediated Zif268 expression in the prefrontal cortex protects against gonadectomy-induced working memory, long-term memory, and social interaction deficits in male rats by Dossat, Amanda M, Jourdi, Hussam, Wright, Katherine N, Strong, Caroline E, Sarkar, Ambalika, Kabbaj, Mohamed

“…Highlights • Gonadectomy negatively impacts PFC Zif268 expression, long-term memory, social interaction, and mood-related behaviors. • mPFC AAV-Zif268…”
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Fluoxetine exposure during adolescence alters responses to aversive stimuli in adulthood by Iñiguez, Sergio D, Alcantara, Lyonna F, Warren, Brandon L, Riggs, Lace M, Parise, Eric M, Vialou, Vincent, Wright, Katherine N, Dayrit, Genesis, Nieto, Steven J, Wilkinson, Matthew B, Lobo, Mary K, Neve, Rachael L, Nestler, Eric J, Bolaños-Guzmán, Carlos A

“…The mechanisms underlying the enduring neurobiological consequences of antidepressant exposure during adolescence are poorly understood. Here, we assessed the…”
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Sex-Dependent Ketamine Addiction-Like Behavior Profile Following Exposure to Chronic Mild Stress by Wright, Katherine N., Hagarty, Devin P., Strong, Caroline E., Schoepfer, Kristin J., Kabbaj, Mohamed

“…Background Ketamine has rapid antidepressant effects and shows great promise as a novel treatment for depression, but its limitations including its abuse…”
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Behavioral and biochemical sensitivity to low doses of ketamine: Influence of estrous cycle in C57BL/6 mice by Dossat, Amanda M., Wright, Katherine N., Strong, Caroline E., Kabbaj, Mohamed

“…Low-dose ketamine is a rapid-acting antidepressant, to which female rodents are more sensitive as compared to males. However, the mechanism mediating this sex…”
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Prediction of individual differences in fear response by novelty seeking, and disruption of contextual fear memory reconsolidation by ketamine by Duclot, Florian, Perez-Taboada, Iara, Wright, Katherine N., Kabbaj, Mohamed

“…Only a portion of the population exposed to trauma will develop persistent emotional alterations characteristic of posttraumatic stress disorder (PTSD), which…”
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Neurobiological Sequelae of Witnessing Stressful Events in Adult Mice by Warren, Brandon L, Vialou, Vincent F, Iñiguez, Sergio D, Alcantara, Lyonna F, Wright, Katherine N, Feng, Jiang, Kennedy, Pamela J, LaPlant, Quincey, Shen, Li, Nestler, Eric J, Bolaños-Guzmán, Carlos A

“…Background It is well known that exposure to severe stress increases the risk for developing mood disorders. However, most chronic stress models in rodents…”
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A Neural System that Represents the Association of Odors with Rewarded Outcomes and Promotes Behavioral Engagement by Gadziola, Marie A., Stetzik, Lucas A., Wright, Katherine N., Milton, Adrianna J., Arakawa, Keiko, del Mar Cortijo, María, Wesson, Daniel W.

“…Odors are well known to elicit strong emotional and behavioral responses that become strengthened throughout learning, yet the specific cellular systems…”
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Sex differences in sub-anesthetic ketamine's antidepressant effects and abuse liability by .Wright, Katherine N, Kabbaj, Mohamed

“…•Clinical studies rarely analyze sex as a factor in ketamine's effects.•Preclinical rodent studies indicate that females are more sensitive to ketamine's…”
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Methyl supplementation attenuates cocaine-seeking behaviors and cocaine-induced c-Fos activation in a DNA methylation-dependent manner by Wright, Katherine N, Hollis, Fiona, Duclot, Florian, Dossat, Amanda M, Strong, Caroline E, Francis, T Chase, Mercer, Roger, Feng, Jian, Dietz, David M, Lobo, Mary Kay, Nestler, Eric J, Kabbaj, Mohamed

“…Epigenetic mechanisms, such as histone modifications, regulate responsiveness to drugs of abuse, such as cocaine, but relatively little is known about the…”
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Reinforcing properties of an intermittent, low dose of ketamine in rats: effects of sex and cycle by Wright, Katherine N., Strong, Caroline E., Addonizio, Marjorie N., Brownstein, Naomi C., Kabbaj, Mohamed

“…Rationale Repeated intermittent exposure to ketamine has rapid and long-lasting antidepressant effects, but the abuse potential has only been assessed at high…”
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Reducing local synthesis of estrogen in the tubular striatum promotes attraction to same-sex odors in female mice by Wright, Katherine N., Johnson, Natalie L., Dossat, Amanda M., Wilson, Jamie T., Wesson, Daniel W.

“…Brain-derived 17β-estradiol (E2) confers rapid effects on neural activity. The tubular striatum (TuS, also called the olfactory tubercle) is both capable of…”
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Sex- and dose-dependent abuse liability of repeated subanesthetic ketamine in rats by Schoepfer, Kristin J., Strong, Caroline E., Saland, Samantha K., Wright, Katherine N., Kabbaj, Mohamed

“…Subanesthetic ketamine (KET) elicits rapid, robust, but transient antidepressant effects. KET's antidepressant actions can be augmented and maintained for a…”
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Publisher Correction: Ventral striatal islands of Calleja neurons control grooming in mice by Zhang, Yun-Feng, Vargas Cifuentes, Luigim, Wright, Katherine N., Bhattarai, Janardhan P., Mohrhardt, Julia, Fleck, David, Janke, Emma, Jiang, Chunjie, Cranfill, Suna L., Goldstein, Nitsan, Schreck, Mary, Moberly, Andrew H., Yu, Yiqun, Arenkiel, Benjamin R., Betley, J. Nicholas, Luo, Wenqin, Stegmaier, Johannes, Wesson, Daniel W., Spehr, Marc, Fuccillo, Marc V., Ma, Minghong

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Sex and Individual Differences in Alcohol Intake Are Associated with Differences in Ketamine Self-Administration Behaviors and Nucleus Accumbens Dendritic Spine Density by Strong, Caroline E, Wright, Katherine N, Kabbaj, Mohamed

“…Clinical and preclinical studies have shown that ketamine, an NMDA receptor antagonist, has promising therapeutic value for the treatment of alcohol use…”
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Regulation of BAZ1A and Nucleosome Positioning in the Nucleus Accumbens in Response to Cocaine by Sun, HaoSheng, Damez-Werno, Diane M, Scobie, Kimberly N, Shao, Ning-Yi, Dias, Caroline, Rabkin, Jacqui, Wright, Katherine N, Mouzon, Ezekiell, Kabbaj, Mohamed, Neve, Rachael, Turecki, Gustavo, Shen, Li, Nestler, Eric J

“…Highlights • BAZ1A is downregulated in the NAc of mice exposed repeatedly to cocaine. • BAZ1A is downregulated in the NAc of cocaine-addicted humans. •…”
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Juvenile administration of concomitant methylphenidate and fluoxetine alters behavioral reactivity to reward- and mood-related stimuli and disrupts ventral tegmental area gene expression in adulthood by Warren, Brandon L, Iñiguez, Sergio D, Alcantara, Lyonna F, Wright, Katherine N, Parise, Eric M, Weakley, Sarah K, Bolaños-Guzmán, Carlos A

“…There is a rise in the concurrent use of methylphenidate (MPH) and fluoxetine (FLX) in pediatric populations. However, the long-term neurobiological…”
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