Search Results - "Wright, Gabriela M."
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CDK4/6 inhibition synergizes with inhibition of P21-Activated Kinases (PAKs) in lung cancer cell lines
Published in PloS one (17-06-2021)“…Theoretically, small molecule CDK4/6 inhibitors (CDK4/6is) represent a logical therapeutic option in non-small cell lung cancers since most of these…”
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Role of Stat3 in Regulating p53 Expression and Function
Published in Molecular and Cellular Biology (01-09-2005)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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CX3CR1 deficiency-induced TIL tumor restriction as a novel addition for CAR-T design in solid malignancies
Published in iScience (21-04-2023)“…Advances in the understanding of the tumor microenvironment have led to development of immunotherapeutic strategies, such as chimeric antigen receptor T cells…”
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4
CDKN1C Negatively Regulates RNA Polymerase II C-terminal Domain Phosphorylation in an E2F1-dependent Manner
Published in The Journal of biological chemistry (26-03-2010)“…CDKN1C is a cyclin-dependent kinase inhibitor and is a candidate tumor suppressor gene. We previously found that the CDKN1C protein represses E2F1-driven…”
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5
CDK4/6 inhibition synergizes with inhibition of P21-Activated Kinases
Published in PloS one (17-06-2021)“…Theoretically, small molecule CDK4/6 inhibitors (CDK4/6is) represent a logical therapeutic option in non-small cell lung cancers since most of these…”
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Journal Article -
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Abstract 4454: Loss of CX3CL1 expression mediates immune evasion in STK11 mutated lung adenocarcinomas
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Immunotherapy has improved survival for many cancer patients, especially for immunogenic malignancies such as lung cancer. However, even in lung…”
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Abstract 5150: Improvement of hematopoiesis in primary low risk MDS with the TGFBR1 investigational inhibitor TP-6379
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Background: The inflammaging modulator, S100A9, mediates immunosuppression and plays a key role in the pathogenesis of low-risk myelodysplastic…”
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CDKN1C (P57KIP2) NEGATIVELY REGULATES E2F1‐DRIVEN TRANSCRIPTION VIA A DIRECT INTERACTION
Published in The FASEB journal (01-04-2009)“…Abstract only Objective To determine the mechanism by which CDKN1C binds and transcriptionally represses E2F1‐driven transcription. We previously found that…”
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