Search Results - "Wrenger, S"

Blood monocyte profiles in COPD patients with PiMM and PiZZ α1-antitrypsin by Stolk, J., Aggarwal, N., Hochnadel, I., Wrenger, S., Martinez-Delgado, B., Welte, T., Yevsa, T., Janciauskiene, S.

“…Human blood monocytes are divided into populations based on the differential expression of CD14 and CD16 receptors: CD14 + CD16(classical),…”
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Does heart surgery change the capacity of α1-antitrypsin to inhibit the ATP-induced release of monocytic interleukin-1β? A preliminary study by Agné, A., Richter, K., Tumpara, S., Sauer, A.-L., Beckert, F., Wrenger, S., Zakrzewicz, A., Hecker, A., Markmann, M., Koch, C., Zajonz, T., Sander, M., Böning, A., Padberg, W., Janciauskiene, S., Grau, V.

“…•Patient α1-antitrypsin inhibits ATP-mediated release of monocytic interleukin-1β.•Heart surgery does not markedly reduce this activity of…”
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Amino-terminal truncation of procalcitonin, a marker for systemic bacterial infections, by dipeptidyl peptidase IV (DP IV) by Wrenger, S., Kähne, T., Bohuon, C., Weglöhner, W., Ansorge, S., Reinhold, D.

“…Increased concentrations of procalcitonin (PCT) are found in the plasma of patients with thermal injury and in patients with sepsis and severe infection,…”
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The role of dipeptidyl peptidase IV (DP IV) enzymatic activity in T cell activation and autoimmunity by Reinhold, Dirk, Kähne, Thilo, Steinbrecher, Andreas, Wrenger, Sabine, Neubert, Klaus, Ansorge, Siegfried, Brocke, Stefan

“…Activated T lymphocytes express high levels of dipeptidyl peptidase IV (DP IV)/CD26. Recent studies support the notion that DP IV may play an important role in…”
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Alpha1-Antitrypsin Therapy Suppresses Acute Rejection in an Orthotopic Murine Lung Transplantation Model by Nakagiri, T., Knöfel, A., Janciauskiene, S., Zardo, P., Wrenger, S., Welte, T., Haverich, A., Warnecke, G.

“…α1-antitrypsin (AAT) is an acute phase protein, major inhibitor of neutrophil proteases and considered as a regulatory protein of broad immune and inflammatory…”
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The effect of anti-CD26 antibodies on DNA synthesis and cytokine production (IL-2, IL-10 and IFN-gamma) depends on enzymatic activity of DP IV/CD26 by Reinhold, D, Kähne, T, Täger, M, Lendeckel, U, Bühling, F, Bank, U, Wrenger, S, Faust, J, Neubert, K, Ansorge, S

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Fibrosis-Related Gene Profiling in Liver Biopsies of PiZZ α1-Antitrypsin Children with Different Clinical Courses by Kamp, Jan C, Kappe, Naomi N, Moro, Carlos Fernández, Fuge, Jan, Kuehnel, Mark P, Wrenger, Sabine, Welte, Tobias, Hoek, Bart van, Jonigk, Danny D, Khedoe, Padmini P S J, Strnad, Pavel, Björnstedt, Mikael, Stolk, Jan, Janciauskiene, Sabina, Nemeth, Antal

“…PiZZ (Glu342Lys) α1-antitrypsin deficiency (AATD) is characterized by intrahepatic AAT polymerization and is a risk factor for liver disease development in…”
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Plasma Acute Phase Proteins as Predictors of Chronic Lung Allograft Dysfunction in Lung Transplant Recipients by Janciauskiene, Sabina, Royer, Pierre-Joseph, Fuge, Jan, Wrenger, Sabine, Chorostowska-Wynimko, Joanna, Falk, Christine, Welte, Tobias, Reynaud-Gaubert, Martine, Roux, Antoine, Tissot, Adrien, Magnan, Antoine

“…Cumulating reports suggest that acute phase proteins (APPs) have diagnostic and prognostic value in different clinical conditions. Among others, APPs are…”
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Attractin, a dipeptidyl peptidase IV/CD26-like enzyme, is expressed on human peripheral blood monocytes and potentially influences monocyte function by Wrenger, Sabine, Faust, Jürgen, Friedrich, Daniel, Hoffmann, Torsten, Hartig, Roland, Lendeckel, Uwe, Kähne, Thilo, Thielitz, Anja, Neubert, Klaus, Reinhold, Dirk

“…The ectoenzyme dipeptidyl peptidase IV (DP IV; CD26) was shown to play a crucial role in T cell activation. Several compounds inhibiting DP IV‐like activity…”
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Dipeptidyl peptidase IV: a cell surface peptidase involved in regulating T cell growth (review) by Kahne, T, Lendeckel, U, Wrenger, S, Neubert, K, Ansorge, S, Reinhold, D

“…The CD26 antigen is identical with the cell surface ectopeptidase dipeptidyl peptidase IV (DP IV, EC 3.4.14.5). The post proline cleaving substrate specificity…”
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Identification of extra- and intracellular alanyl aminopeptidases as new targets to modulate keratinocyte growth and differentiation by Thielitz, Anja, Bukowska, A., Wolke, C., Vetter, Robert, Lendeckel, Uwe, Wrenger, Sabine, Hashimoto, Yuichi, Ansorge, Siegfried, Gollnick, Harald, Reinhold, Dirk

“…Aminopeptidase inhibitors strongly affect proliferation, differentiation, and function of immune cells and show therapeutic potential in inflammatory…”
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Non-substrate peptides influencing dipeptidyl peptidase IV/CD26 activity and immune cell function by Wrenger, Sabine, Faust, Jurgen, Mrestani-Klaus, Carmen, Brandt, Wolfgang, Thielitz, Anja, Neubert, Klaus, Reinhold, Dirk

“…Investigations using inhibitors of dipeptidyl peptidase IV (DP IV) activities and DP IV-/- mice indicated an immunoregulatory role of DP IV that could not be…”
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Down-regulation of T cell activation following inhibition of dipeptidyl peptidase IV/CD26 by the N-terminal part of the thromboxane A2 receptor by Wrenger, S, Faust, J, Mrestani-Klaus, C, Fengler, A, Stockel-Maschek, A, Lorey, S, Kahne, T, Brandt, W, Neubert, K, Ansorge, S, Reinhold, D

“…Using synthetic inhibitors, it has been shown that the ectopeptidase dipeptidyl peptidase IV (DP IV) (CD26) plays an important role in the activation and…”
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CD26/DP IV in T cell activation and autoimmunity by Preller, Vera, Gerber, Annegret, Togni, Mauro, Wrenger, Sabine, Schraven, Burkhart, Röcken, Christoph, Marguet, Didier, Ansorge, Siegfried, Brocke, Stefan, Reinhold, Dirk

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Expression and Activity of Ectopeptidases in Fibrillating Human Atria by Lendeckel, Uwe, Arndt, Marco, Wrenger, Sabine, Nepple, Karen, Huth, Christof, Ansorge, Siegfried, Klein, Helmut U., Goette, Andreas

“…Recent studies have demonstrated that atrial fibrillation (AF) occurs in the presence of degenerative changes of atrial tissue. In contrast, bradykinin (BK)…”
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The N-terminal Structure of HIV-1 Tat Is Required for Suppression of CD26-dependent T Cell Growth by Wrenger, Sabine, Hoffmann, Torsten, Faust, Jürgen, Mrestani-Klaus, Carmen, Brandt, Wolfgang, Neubert, Klaus, Kraft, Margot, Olek, Sven, Frank, Rainer, Ansorge, Siegfried, Reinhold, Dirk

“…Evidence exists that the human immunodeficiency virus-1 (HIV-1) transactivator Tat occurs extracellularly and is involved in the immunosuppression of…”
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Down-regulation of T Cell Activation following Inhibition of Dipeptidyl Peptidase IV/CD26 by the N-terminal Part of the Thromboxane A2 Receptor by Wrenger, Sabine, Faust, Jürgen, Mrestani-Klaus, Carmen, Fengler, Annett, Stöckel-Maschek, Angela, Lorey, Susan, Kähne, Thilo, Brandt, Wolfgang, Neubert, Klaus, Ansorge, Siegfried, Reinhold, Dirk

“…Using synthetic inhibitors, it has been shown that the ectopeptidase dipeptidyl peptidase IV (DP IV) (CD26) plays an important role in the activation and…”
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Different modes of dipeptidyl peptidase IV (CD26) inhibition by oligopeptides derived from the N‐terminus of HIV‐1 Tat indicate at least two inhibitor binding sites by Lorey, Susan, Stöckel‐Maschek, Angela, Faust, Jürgen, Brandt, Wolfgang, Stiebitz, Beate, Gorrell, Mark D., Kähne, Thilo, Mrestani‐Klaus, Carmen, Wrenger, Sabine, Reinhold, Dirk, Ansorge, Siegfried, Neubert, Klaus

“…Dipeptidyl peptidase IV (DP IV, CD26) plays an essential role in the activation and proliferation of lymphocytes, which is shown by the immunosuppressive…”
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Dipeptidyl peptidase IV inhibitors with the N-terminal MXP sequence: structure-activity-relationships by Faust, Jürgen, Fuchs, Petra, Wrenger, Sabine, Reinhold, Dirk, Stöckel-Maschek, Angela, Kähne, Thilo, Ansorge, Siegfried, Neubert, Klaus

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New results on the conformations of potent DP IV (CD26) inhibitors bearing the N-terminal MWP structural motif by Mrestani-Klaus, Carmen, Brandt, Wolfgang, Faust, Jürgen, Wrenger, Sabine, Reinhold, Dirk, Ansorge, Siegfried, Neubert, Klaus

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