Search Results - "Wren, B W"

Zoonotic Transfer of Clostridium difficile Harboring Antimicrobial Resistance between Farm Animals and Humans by Knetsch, C W, Kumar, N, Forster, S C, Connor, T R, Browne, H P, Harmanus, C, Sanders, I M, Harris, S R, Turner, L, Morris, T, Perry, M, Miyajima, F, Roberts, P, Pirmohamed, M, Songer, J G, Weese, J S, Indra, A, Corver, J, Rupnik, M, Wren, B W, Riley, T V, Kuijper, E J, Lawley, T D

“…The emergence of as a significant human diarrheal pathogen is associated with the production of highly transmissible spores and the acquisition of…”
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In vitro and in vivo properties of the bovine antimicrobial peptide, Bactenecin 5 by Price, R L, Bugeon, L, Mostowy, S, Makendi, C, Wren, B W, Williams, H D, Willcocks, S J

“…Antimicrobial peptides (AMP), part of the innate immune system, are well studied for their ability to kill pathogenic microorganisms. However, many also…”
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Biofilm formation in Campylobacter jejuni by Joshua, G. W. P, Guthrie-Irons, C, Karlyshev, A. V, Wren, B. W

“…Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK Correspondence B. W. Wren…”
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Comparative Phylogenomics of Clostridium difficile Reveals Clade Specificity and Microevolution of Hypervirulent Strains by STABLER, R. A, GERDING, D. N, SONGER, J. G, DRUDY, D, BRAZIER, J. S, TRINH, H. T, WITNEY, A. A, HINDS, J, WREN, B. W

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The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences by Parkhill, J, Wren, B. W, Mungall, K, Ketley, J. M, Churcher, C, Basham, D, Chillingworth, T, Davies, R. M, Feltwell, T, Holroyd, S, Jagels, K, Karlyshev, A. V, Moule, S, Pallen, M. J, Penn, C. W, Quail, M. A, Rajandream, M-A, Rutherford, K. M, van Vliet, A. H. M, Whitehead, S, Barrell, B. G

“…Campylobacter jejuni, from the delta-epsilon group of proteobacteria, is a microaerophilic, Gram-negative, flagellate, spiral bacterium-properties it shares…”
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Development and Application of an Insertional System for Gene Delivery and Expression in Campylobacter jejuni by Karlyshev, A. V, Wren, B. W

“…The genetic investigation of Campylobacter jejuni, an important gastrointestinal pathogen, has been hampered by the lack of an efficient system for…”
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Genome sequence of Yersinia pestis , the causative agent of plague by Parkhill, J, Wren, B. W, Thomson, N. R, Titball, R. W, Holden, M. T. G, Prentice, M. B, Sebaihia, M, James, K. D, Churcher, C, Mungall, K. L, Baker, S, Basham, D, Bentley, S. D, Brooks, K, Cerdeño-Tárraga, A. M, Chillingworth, T, Cronin, A, Davies, R. M, Davis, P, Dougan, G, Feltwell, T, Hamlin, N, Holroyd, S, Jagels, K, Karlyshev, A. V, Leather, S, Moule, S, Oyston, P. C. F, Quail, M, Rutherford, K, Simmonds, M, Skelton, J, Stevens, K, Whitehead, S, Barrell, B. G

“…The Gram-negative bacterium Yersinia pestis is the causative agent of the systemic invasive infectious disease classically referred to as plague, and has been…”
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The Campylobacter jejuni general glycosylation system is important for attachment to human epithelial cells and in the colonization of chicks by Karlyshev, A. V, Everest, P, Linton, D, Cawthraw, S, Newell, D. G, Wren, B. W

“…1 London School of Hygiene and Tropical Medicine, University of London, Keppel Street, London EC1A 7HT, UK 2 Department of Veterinary Pathology, Glasgow…”
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Campylobacter jejuni Gene Expression in the Chick Cecum: Evidence for Adaptation to a Low-Oxygen Environment by Woodall, C. A, Jones, M. A, Barrow, P. A, Hinds, J, Marsden, G. L, Kelly, D. J, Dorrell, N, Wren, B. W, Maskell, D. J

“…Transcriptional profiling of Campylobacter jejuni during colonization of the chick cecum identified 59 genes that were differentially expressed in vivo…”
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Development of Signature-Tagged Mutagenesis in Burkholderia pseudomallei To Identify Genes Important in Survival and Pathogenesis by Cuccui, J, Easton, A, Chu, K.K, Bancroft, G.J, Oyston, P.C.F, Titball, R.W, Wren, B.W

“…Burkholderia pseudomallei, the causative agent of melioidosis, is an important human pathogen in Southeast Asia and northern Australia for which a vaccine is…”
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A Caenorhabditis elegans model of Yersinia infection: biofilm formation on a biotic surface by Joshua, G. W. P, Karlyshev, A. V, Smith, M. P, Isherwood, K. E, Titball, R. W, Wren, B. W

“…1 London School of Hygiene and Tropical Medicine, Dept Infectious and Tropical Diseases, Keppel St, London WC1E 7HT, UK 2 DSTL, Porton Down, Salisbury SP4 0JQ,…”
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Campylobacter jejuni Cocultured with Epithelial Cells Reduces Surface Capsular Polysaccharide Expression by Corcionivoschi, N, Clyne, M, Lyons, A, Elmi, A, Gundogdu, O, Wren, B.W, Dorrell, N, Karlyshev, A.V, Bourke, B

“…The host cell environment can alter bacterial pathogenicity. We employed a combination of cellular and molecular techniques to study the expression of…”
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Molecular detection identified a type six secretion system in Campylobacter jejuni from various sources but not from human cases by Siddiqui, F, Champion, O, Akram, M, Studholme, D, Eqani, S.A.M.A.S, Wren, B.W, Titball, R, Bokhari, H

“…AIM: To determine the presence of the T6SS in Campylobacter jejuni from diverse sources. METHODS AND RESULTS: The recently identified type VI secretion system…”
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Genome Sequence of the Emerging Pathogen Helicobacter canadensis by LOMAN, N. J, SNYDER, L. A. S, LINTON, J. D, LANGDON, R, LAWSON, A. J, WEINSTOCK, G. M, WREN, B. W, PALLEN, M. J

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The Clostridium difficile PCR ribotype 027 lineage: a pathogen on the move by Valiente, E., Cairns, M.D., Wren, B.W.

“…Clostridium difficile is a Gram-positive, spore-forming, human and animal pathogen that is the major cause of antibiotic-associated diarrhoea worldwide. The…”
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Application of high-density array-based signature-tagged mutagenesis to discover novel Yersinia virulence-associated genes by KARLYSHEV, A. V, OYSTON, P. C. F, WILLIAMS, K, CLARK, G. C, TITBALL, R. W, WINZELER, E. A, WREN, B. W

“…Yersinia pestis, the causative agent of plague, and the enteropathogen Yersinia pseudotuberculosis have nearly identical nucleotide similarity yet cause…”
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Revisiting aminocoumarins for the treatment of melioidosis by Willcocks, S.J., Cia, F., Francisco, A.F., Wren, B.W.

“…•Aminocoumarins can be used to treat acute pulmonary melioidosis in a murine model.•Formulation with l-tyrosine or dl-tryptophan enhances the bioactivity of…”
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Genomic Epidemiology of a Protracted Hospital Outbreak Caused by a Toxin A-Negative Clostridium difficile Sublineage PCR Ribotype 017 Strain in London, England by Cairns, M D, Preston, M D, Lawley, T D, Clark, T G, Stabler, R A, Wren, B W

“…Clostridium difficile remains the leading cause of nosocomial diarrhea worldwide, which is largely considered to be due to the production of two potent toxins:…”
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The Response Regulator PhoP Is Important for Survival under Conditions of Macrophage-Induced Stress and Virulence in Yersinia pestis by OYSTON, P. C. F, DORRELL, N, WILLIAMS, K, LI, S.-R, GREEN, M, TITBALL, R. W, WREN, B. W

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The recent emergence of a highly related virulent Clostridium difficile clade with unique characteristics by Shaw, H.A., Preston, M.D., Vendrik, K.E.W., Cairns, M.D., Browne, H.P., Stabler, R.A., Crobach, M.J.T., Corver, J., Pituch, H., Ingebretsen, A., Pirmohamed, M., Faulds-Pain, A., Valiente, E., Lawley, T.D., Fairweather, N.F., Kuijper, E.J., Wren, B.W.

“…Clostridium difficile is a major global human pathogen divided into five clades, of which clade 3 is the least characterized and consists predominantly of PCR…”
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