Search Results - "Wree, Andreas"

Experimental Intrastriatal Applications of Botulinum Neurotoxin-A: A Review by Hawlitschka, Alexander, Wree, Andreas

“…Parkinson's disease (PD) is one of the most frequent neurodegenerative disorders. Its main pathophysiological characteristic is the loss of dopaminergic…”
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Transmembrane protein 119 is neither a specific nor a reliable marker for microglia by Vankriekelsvenne, Elise, Chrzanowski, Uta, Manzhula, Katerina, Greiner, Theresa, Wree, Andreas, Hawlitschka, Alexander, Llovera, Gemma, Zhan, Jiangshan, Joost, Sarah, Schmitz, Christoph, Ponsaerts, Peter, Amor, Sandra, Nutma, Erik, Kipp, Markus, Kaddatz, Hannes

“…Microglia are the resident innate immune cells of the central nervous system (CNS) parenchyma. To determine the impact of microglia on disease development and…”
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Current Challenges in Understanding the Cellular and Molecular Mechanisms in Niemann-Pick Disease Type C1 by Bräuer, Anja U, Kuhla, Angela, Holzmann, Carsten, Wree, Andreas, Witt, Martin

“…Rare diseases are a heterogeneous group of very different clinical syndromes. Their most common causes are defects in the hereditary material, and they can…”
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Distribution of Cleaved SNAP-25 in the Rat Brain, following Unilateral Injection of Botulinum Neurotoxin-A into the Striatum by Schümann, Friederike, Schmitt, Oliver, Wree, Andreas, Hawlitschka, Alexander

“…In Parkinson's disease, hypercholinism in the striatum occurs, with the consequence of disturbed motor functions. Direct application of Botulinum neurotoxin-A…”
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Direct Visualization and Mapping of the Spatial Course of Fiber Tracts at Microscopic Resolution in the Human Hippocampus by Zeineh, Michael M, Palomero-Gallagher, Nicola, Axer, Markus, Gräßel, David, Goubran, Maged, Wree, Andreas, Woods, Roger, Amunts, Katrin, Zilles, Karl

“…While hippocampal connectivity is essential to normal memory function, our knowledge of human hippocampal circuitry is largely inferred from animal studies…”
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Gender-Specific Effects of Two Treatment Strategies in a Mouse Model of Niemann-Pick Disease Type C1 by Holzmann, Carsten, Witt, Martin, Rolfs, Arndt, Antipova, Veronica, Wree, Andreas

“…In a mouse model of Niemann-Pick disease type C1 (NPC1), a combination therapy (COMBI) of miglustat (MIGLU), the neurosteroid allopregnanolone (ALLO) and the…”
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Lifelong caloric restriction increases working memory in mice by Kuhla, Angela, Lange, Sophie, Holzmann, Carsten, Maass, Fabian, Petersen, Jana, Vollmar, Brigitte, Wree, Andreas

“…Caloric restriction (CR) is argued to positively affect general health, longevity and the normally occurring age-related reduction of cognition. This issue is…”
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Suppression of TGF-β pathway by pirfenidone decreases extracellular matrix deposition in ocular fibroblasts in vitro by Stahnke, Thomas, Kowtharapu, Bhavani S, Stachs, Oliver, Schmitz, Klaus-Peter, Wurm, Johannes, Wree, Andreas, Guthoff, Rudolf Friedrich, Hovakimyan, Marina

“…In glaucoma surgery, fibrotic processes occur, leading to impairment of liquid outflow. Activated fibroblasts are responsible for postoperative scarring. The…”
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Antidepressant-Like Properties of Intrastriatal Botulinum Neurotoxin-A Injection in a Unilateral 6-OHDA Rat Model of Parkinson's Disease by Antipova, Veronica, Holzmann, Carsten, Hawlitschka, Alexander, Witt, Martin, Wree, Andreas

“…Parkinson's patients often suffer from depression and anxiety, for which there are no optimal treatments. Hemiparkinsonian (hemi-PD) rats were used to test…”
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Botulinum Neurotoxin-A Injected Intrastriatally into Hemiparkinsonian Rats Improves the Initiation Time for Left and Right Forelimbs in Both Forehand and Backhand Directions by Antipova, Veronica, Holzmann, Carsten, Hawlitschka, Alexander, Wree, Andreas

“…Forelimb stepping is a widely used test for the assessment of forelimb akinesia in hemiparkinsonian (hemi-PD) rats. The initiation time (IT) is considered the…”
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Organ Weights in NPC1 Mutant Mice Partly Normalized by Various Pharmacological Treatment Approaches by Antipova, Veronica, Steinhoff, Lisa-Marie, Holzmann, Carsten, Rolfs, Arndt, Hempel, Carlos Junior, Witt, Martin, Wree, Andreas

“…Niemann-Pick Type C1 (NPC1, MIM 257220) is a rare, progressive, lethal, inherited autosomal-recessive endolysosomal storage disease caused by mutations in the…”
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Course and Relation of the Facial Vessels-An Anatomical Study by Siwetz, Martin, Widni-Pajank, Hannes, Hammer, Niels, Bruneder, Simon, Wree, Andreas, Antipova, Veronica

“…: Facial vascular anatomy plays a pivotal role in both physiological context and in surgical intervention. While data exist on the individual course of the…”
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The initial engraftment of tumor cells is critical for the future growth pattern: a mathematical study based on simulations and animal experiments by Hoffmann, Bertin, Lange, Tobias, Labitzky, Vera, Riecken, Kristoffer, Wree, Andreas, Schumacher, Udo, Wedemann, Gero

“…Xenograft mouse tumor models are used to study mechanisms of tumor growth and metastasis formation and to investigate the efficacy of different therapeutic…”
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Surface Modification of Biodegradable Polymers towards Better Biocompatibility and Lower Thrombogenicity by Rudolph, Andreas, Teske, Michael, Illner, Sabine, Kiefel, Volker, Sternberg, Katrin, Grabow, Niels, Wree, Andreas, Hovakimyan, Marina

“…Drug-eluting stents (DES) based on permanent polymeric coating matrices have been introduced to overcome the in stent restenosis associated with bare metal…”
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Neointimal fibrotic lead encapsulation – Clinical challenges and demands for implantable cardiac electronic devices by Keiler, Jonas, PhD, Schulze, Marko, Dipl.-Biol, Sombetzki, Martina, PhD, Heller, Thomas, PhD, Tischer, Tina, PhD, Grabow, Niels, PhD, Wree, Andreas, PhD, Bänsch, Dietmar, PhD

“…Abstract Every tenth patient with a cardiac pacemaker or implantable cardioverter-defibrillator implanted is expected to have at least one lead problem in his…”
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Evaluation of 3D Footprint Morphology of Knee-Related Muscle Attachments Based on CT Data Reconstruction: A Feasibility Study by Neumann, Anne-Marie, Kebbach, Maeruan, Bader, Rainer, Hildebrandt, Guido, Wree, Andreas

“…A three-dimensional (3D) understanding of muscle attachment footprints became increasingly relevant for musculoskeletal modeling. The established method to…”
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Repeated Intrastriatal Botulinum Neurotoxin-A Injection in Hemiparkinsonian Rats Increased the Beneficial Effect on Rotational Behavior by Hawlitschka, Alexander, Holzmann, Carsten, Wree, Andreas, Antipova, Veronica

“…Injection of botulinum neurotoxin-A (BoNT-A) into the striatum of hemiparkinsonian (hemi-PD) rats reduced apomorphine-induced rotation behavior significantly,…”
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Growth/differentiation factor-15 deficiency compromises dopaminergic neuron survival and microglial response in the 6-hydroxydopamine mouse model of Parkinson's disease by Machado, Venissa, Haas, Stefan J.-P, von Bohlen und Halbach, Oliver, Wree, Andreas, Krieglstein, Kerstin, Unsicker, Klaus, Spittau, Björn

“…Abstract Growth/differentiation factor-15 (Gdf-15) is a member of the TGF-β superfamily and a pleiotropic, widely distributed cytokine, which has been shown to…”
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PRG3 and PRG5 C-Termini: Important Players in Early Neuronal Differentiation by Brandt, Nicola, Willmer, Jan Philipp, Ayon-Olivas, Maurilyn S., Banicka, Veronika, Witt, Martin, Wree, Andreas, Groß, Isabel, Gläser, Anne, Hausmann, Jens, Bräuer, Anja U.

“…The functional importance of neuronal differentiation of the transmembrane proteins’ plasticity-related genes 3 (PRG3) and 5 (PRG5) has been shown. Although…”
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A Rare Case of Facial Artery Branching—A Review of the Literature and a Case Report with Clinical Implications by Siwetz, Martin, Turnowsky, Nicol, Hammer, Niels, Pretterklieber, Michael, Wree, Andreas, Antipova, Veronica

“…Background and Objectives: Vascular variations appear as morphologically distinct patterns of blood diverging from the most commonly observed vessel patterns…”
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