Search Results - "Wrede, CE"

Outcome of patients with acute, necrotizing pancreatitis requiring drainage-does drainage size matter by Bruennler, T, Langgartner, J, Lang, S, Wrede, C E, Klebl, F, Zierhut, S, Siebig, S, Mandraka, F, Rockmann, F, Salzberger, B, Feuerbach, S, Schoelmerich, J, Hamer, O W

“…AIM： To assess the outcome of patients with acute necrotizing pancreatitis treated by percutaneous drainage with special focus on the influence of drainage…”
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Reasons for emergency department visits – Results of a patient survey by Geissler, A, Somasundaram, R, Leidel, BA, Wrede, CE

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Fatty acid and phorbol ester-mediated interference of mitogenic signaling via novel protein kinase C isoforms in pancreatic beta-cells (INS-1) by Wrede, CE, Dickson, LM, Lingohr, MK, Briaud, I, Rhodes, CJ

“…It is possible that activation of protein kinase C (PKC) isoforms by free fatty acids (FFA) plays a role in the failure of pancreatic beta-cell mass expansion…”
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Protein Kinase B/Akt Prevents Fatty Acid-induced Apoptosis in Pancreatic β-Cells (INS-1) by Wrede, Christian E., Dickson, Lorna M., Lingohr, Melissa K., Briaud, Isabelle, Rhodes, Christopher J.

“…Free fatty acids (FFA) have been reported to reduce pancreatic β-cell mitogenesis and to increase apoptosis. Here we show that the FFA, oleic acid, increased…”
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Insulin-sparing effects of troglitazone in rat pancreatic islets by Bollheimer, LC, Troll, S, Landauer, H, Wrede, CE, Scholmerich, J, Buettner, R

“…Thiazolidinediones (TZDs) have been suggested to act beneficially on pancreatic islet function and on beta-cell viability but data concerning direct effects on…”
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Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic beta-cell line INS-1 by Cousin, S P, Hügl, S R, Wrede, C E, Kajio, H, Myers, Jr, M G, Rhodes, C J

“…Pancreatic beta-cell mitogenesis is increased by insulin-like growth factor I (IGF-I) in a glucose-dependent manner. In this study it was found that…”
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Association between serum ferritin and the insulin resistance syndrome in a representative population by Wrede, C E, Buettner, R, Bollheimer, L C, Schölmerich, J, Palitzsch, K-D, Hellerbrand, C

“…Objective: Unexplained hepatic iron overload with increased serum ferritin (SF) values has been associated with the insulin resistance syndrome (IRS), defined…”
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Differential activation mechanisms of Erk-1/2 and p70(S6K) by glucose in pancreatic beta-cells by Briaud, Isabelle, Lingohr, Melissa K, Dickson, Lorna M, Wrede, Christian E, Rhodes, Christopher J

“…Glucose can activate the mitogen-activated kinases, Erk-1/2, and the ribosomal-S6 kinase, p70(S6K), in beta-cells, contributing to an increase in mitogenesis…”
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Decreasing IRS-2 expression in pancreatic β-cells (INS-1) promotes apoptosis, which can be compensated for by introduction of IRS-4 expression by Lingohr, Melissa K., Dickson, Lorna M., Wrede, Christian E., Briaud, Isabelle, McCuaig, Jill F., Myers, Martin G., Rhodes, Christopher J.

“…IRS-2 plays a pivotal role in the control of pancreatic β-cell growth. Here, the effect of altering IRS-2 expression levels in the pancreatic β-cell line,…”
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Optimized Multidetector Computed Tomographic Protocol for the Diagnosis of Active Obscure Gastrointestinal Bleeding: A Feasibility Study by Heiss, P, Zorger, N, Hamer, O W, Seitz, J, Muller-Wille, R, Roller, M, Herold, T, Scholmerich, J, Feuerbach, S, Wrede, CE

“…Objective: The purpose of this feasibility study was to prospectively evaluate an optimized multidetector computed tomographic protocol for the diagnosis of…”
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Glucagon production of the rat insulinoma cell line INS-1—A quantitative comparison with primary rat pancreatic islets by Bollheimer, L. Cornelius, Wrede, Christian E., Rockmann, Felix, Ottinger, Iris, Schölmerich, Jürgen, Buettner, Roland

“…The rat insulinoma cell line INS-1 is the most commonly used clonal cell model in pancreatic β-cell research. Considering the multihormonality of many…”
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Stimulatory short-term effects of free fatty acids on glucagon secretion at low to normal glucose concentrations by BOLLHEIMER, L. Cornelius, LANDAUER, Heike C, TROLL, Stephanie, SCHWEIMER, Joachim, WREDE, Christian E, SCHÖLMERICH, Jürgen, BUETTNER, Roland

“…While free fatty acids (FFA) are well known as insulin secretagogues, their effects on pancreatic alpha cells have been mostly neglected. In the present study…”
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IRS-3 inhibits IRS-2-mediated signaling in pancreatic β-cells by Lingohr, Melissa K., Dickson, Lorna M., Wrede, Christian E., McCuaig, Jill F., Myers, Martin G., Rhodes, Christopher J.

“…IRS-2 plays an important role in the control of pancreatic β-cell growth, however it is unclear if other IRS family members are also involved. Using…”
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Intracellular depletion of insulin: a comparative study with palmitate, oleate and elaidate in INS-1 cells by Bollheimer, LC, Kemptner, DM, Kagerbauer, SM, Kestler, TM, Wrede, CE, Buettner, R

“…OBJECTIVE: Free fatty acids (FFAs) deplete the intracellular insulin stores of pancreatic beta-cells. It has been suggested that this results from a lipotoxic…”
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Correlation between iron status and genetic hemochromatosis (codon C282Y) in a large German population by Wrede, Christian E, Hutzler, Stefanie, Bollheimer, L Cornelius, Buettner, Roland, Hellerbrand, Claus, Schöelmerich, Jürgen, Palitzsch, Klaus-Dieter

“…Genetic hemochromatosis leads to iron overload in many tissues and may lead to liver cirrhosis and hepatocellular carcinoma. Early diagnosis and therapy are…”
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