Search Results - "Wozniak, Karen L."
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Induction of memory-like dendritic cell responses in vivo
Published in Nature communications (04-07-2019)“…Dendritic cells (DCs), a vital component of the innate immune system, are considered to lack antigen specificity and be devoid of immunological memory…”
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STAT1 signaling within macrophages is required for antifungal activity against Cryptococcus neoformans
Published in Infection and immunity (01-12-2015)“…Cryptococcus neoformans, the predominant etiological agent of cryptococcosis, is an opportunistic fungal pathogen that primarily affects AIDS patients and…”
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Pulmonary Macrophage and Dendritic Cell Responses to Cryptococcus neoformans
Published in Frontiers in cellular and infection microbiology (11-02-2020)“…The fungal pathogen can cause life-threatening infections in immune compromised individuals. This pathogen is typically acquired via inhalation, and enters the…”
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4
Non-Antibiotic Antimony-Based Antimicrobials
Published in Molecules (Basel, Switzerland) (23-10-2022)“…A series of the eight novel organoantimony(V) cyanoximates of Sb(C6H5)4L composition was synthesized using the high-yield heterogeneous metathesis reaction…”
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IFN-γ immune priming of macrophages in vivo induces prolonged STAT1 binding and protection against Cryptococcus neoformans
Published in PLoS pathogens (01-10-2018)“…Development of vaccines against opportunistic infections is difficult as patients most at risk of developing disease are deficient in aspects of the adaptive…”
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STAT1 signaling is essential for protection against Cryptococcus neoformans infection in mice
Published in The Journal of immunology (1950) (15-10-2014)“…Nonprotective immune responses to highly virulent Cryptococcus neoformans strains, such as H99, are associated with Th2-type cytokine production, alternatively…”
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Role of IL-17A on resolution of pulmonary C. neoformans infection
Published in PloS one (17-02-2011)“…The current studies evaluated the role of interleukin (IL)-17A in the induction of protective immunity against pulmonary cryptococcosis in mice. Protection…”
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Borrelia peptidoglycan interacting Protein (BpiP) contributes to the fitness of Borrelia burgdorferi against host-derived factors and influences virulence in mouse models of Lyme disease
Published in PLoS pathogens (01-04-2021)“…The Peptidoglycan (PG) cell wall of the Lyme disease (LD) spirochete, Borrelia burgdorferi (Bb), contributes to structural and morphological integrity of Bb;…”
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Dectin-3 Is Not Required for Protection against Cryptococcus neoformans Infection
Published in PloS one (20-01-2017)“…C-type lectin receptors (CLRs) are diverse, trans-membrane proteins that function as pattern recognition receptors (PRRs) which are necessary for orchestrating…”
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Cryptococcus and Phagocytes: Complex Interactions that Influence Disease Outcome
Published in Frontiers in microbiology (09-02-2016)“…Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening disease. These fungi commonly enter their host via inhalation into the…”
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Antifungal activity of dendritic cell lysosomal proteins against Cryptococcus neoformans
Published in Scientific reports (30-06-2021)“…Cryptococcal meningitis is a life-threatening disease among immune compromised individuals that is caused by the opportunistic fungal pathogen Cryptococcus…”
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Innate Pulmonary Phagocytes and Their Interactions with Pathogenic Cryptococcus Species
Published in Journal of fungi (Basel) (27-05-2023)“…is an opportunistic fungal pathogen that causes over 180,000 annual deaths in HIV/AIDS patients. Innate phagocytes in the lungs, such as dendritic cells (DCs)…”
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Transcriptional Changes in Pulmonary Phagocyte Subsets Dictate the Outcome Following Interaction With The Fungal Pathogen Cryptococcus neoformans
Published in Frontiers in immunology (28-09-2021)“…With over 220,000 cases and 180,000 deaths annually, is the most common cause of fungal meningitis and a leading cause of death in HIV/AIDS patients in…”
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The acute neutrophil response mediated by S100 alarmins during vaginal Candida infections is independent of the Th17-pathway
Published in PloS one (25-09-2012)“…Vulvovaginal candidiasis (VVC) caused by Candida albicans affects a significant number of women during their reproductive ages. Clinical observations revealed…”
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Antifungal activity of eumelanin-inspired indoylenepheyleneethynylene against Cryptococcus neoformans
Published in Frontiers in microbiology (16-01-2024)“…is an opportunistic fungal pathogen that causes meningitis in >152,000 immunocompromised individuals annually, leading to 112,000 yearly deaths. The four…”
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Protective interaction of human phagocytic APC subsets with Cryptococcus neoformans induces genes associated with metabolism and antigen presentation
Published in Frontiers in immunology (15-11-2022)“…Cryptococcal meningitis is the most common cause of meningitis among HIV/AIDS patients in sub-Saharan Africa, and worldwide causes over 223,000 cases leading…”
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Development of protective inflammation and cell-mediated immunity against Cryptococcus neoformans after exposure to hyphal mutants
Published in mBio (06-10-2015)“…Morphological switch is tightly coupled with the pathogenesis of many dimorphic fungal pathogens. Cryptococcus neoformans, the major causative agent of…”
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Cryptococcus neoformans Enters the Endolysosomal Pathway of Dendritic Cells and Is Killed by Lysosomal Components
Published in Infection and Immunity (01-10-2008)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Characterization of IL-22 and antimicrobial peptide production in mice protected against pulmonary Cryptococcus neoformans infection
Published in Microbiology (Society for General Microbiology) (01-07-2014)“…Cryptococcus neoformans is a significant cause of fungal meningitis in patients with impaired T cell-mediated immunity (CMI). Experimental pulmonary infection…”
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Dendritic Cells: Multifunctional Roles in Host Defenses to Cryptococcus Infections
Published in Journal of fungi (Basel) (26-10-2023)“…Fungal infections are an increasingly growing public health concern, and is one of the most problematic fungal organisms causing substantial mortality and…”
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