Search Results - "Wozney, J.M"
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Recombinant human bone morphogenetic protein-2 promotes wound healing in rat periodontal fenestration defects
Published in Journal of dental research (01-08-1997)“…Although there is considerable interest in the use of bone morphogenetic protein (BMP) to promote periodontal regeneration, little is known of its effects on…”
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Effects of recombinant human bone morphogenetic protein-2 on differentiation of cells isolated from human bone, muscle, and skin
Published in Bone (New York, N.Y.) (01-09-1998)“…We investigated the effects of recombinant human BMP-2 (rhBMP-2) on differentiation of cells isolated from human bone, muscle, and skin. Cells isolated from…”
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A mammalian serine/threonine kinase receptor specifically binds BMP-2 and BMP-4
Published in Biochemical and biophysical research communications (30-12-1994)“…Bone morphogenetic proteins (BMPs) are a class of related growth and differentiation factors within the TGF-beta superfamily of proteins which are known to…”
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Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones
Published in The EMBO journal (01-08-1986)“…cDNAs which encode bone gla protein (BGP), an abundant gamma‐carboxylated protein of bone, have been cloned from rat and mouse osteosarcoma cell lines. DNA…”
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Protein-based tissue engineering in bone and cartilage repair
Published in Current opinion in biotechnology (01-10-2004)“…Bioactive proteins signal host or transplanted cells to form the desired tissue type. Matrix systems are utilized to locally deliver the proteins and to…”
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rhBMP-2 injected in a calcium phosphate paste (α-BSM) accelerates healing in the rabbit ulnar osteotomy model
Published in Journal of orthopaedic research (01-11-2003)“…This study evaluated the ability of recombinant human bone morphogenetic protein-2 (rhBMP-2) delivered in an injectable calcium phosphate carrier (α-BSM) to…”
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Locally delivered rhBMP-2 enhances bone ingrowth and gap healing in a canine model
Published in Journal of orthopaedic research (2004)“…The purpose of the present study was to determine if recombinant human bone morphogenetic protein-2 (rhBMP-2) enhances bone ingrowth into porous-coated…”
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Recombinant Human Bone Morphogenetic Protein Induces Bone Formation
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-1990)“…We have purified and characterized active recombinant human bone morphogenetic protein (BMP) 2A. Implantation of the recombinant protein in rats showed that a…”
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Novel Regulators of Bone Formation: Molecular Clones and Activities
Published in Science (American Association for the Advancement of Science) (16-12-1988)“…Protein extracts derived from bone can initiate the process that begins with cartilage formation and ends in de novo bone formation. The critical components of…”
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Engineering new bone with bone morphogenic proteins
Published in Annales d'endocrinologie (01-04-2006)Get full text
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Biotinated bone morphogenetic protein-2: In vivo and in vitro activity
Published in Biotechnology and bioengineering (20-12-1999)“…Recombinant human bone morphogenetic protein‐2 (rhBMP‐2) was biotinated, and the bioactivity of biotinated protein was assessed in vitro (alkaline phosphate…”
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The effects of recombinant human bone morphogenetic protein-2 on the rate of fracture healing in the rabbit
Published in Bone (New York, N.Y.) (01-12-1995)Get full text
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Molecular cloning of a cDNA encoding human antihaemophilic factor
Published in Nature (London) (1984)“…A complete copy of the mRNA sequences encoding human coagulation factor VIII:C has been cloned and expressed. The DNA sequence predicts a single chain…”
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