Search Results - "Worrad, Diane M"

Regulation of Transcriptional Activity during the First and Second Cell Cycles in the Preimplantation Mouse Embryo by Aoki, Fugaku, Worrad, Diane M., Schultz, Richard M.

“…Transcription of endogenous genes in preimplantation 1- and 2-cell mouse embryos was determined by monitoring the incorporation of BrUTP by plasma…”
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Embryonic Heart Failure in NFATc1−/− Mice: Novel Mechanistic Insights From In Utero Ultrasound Biomicroscopy by Phoon, Colin K.L, Ji, Rui Ping, Aristizábal, Orlando, Worrad, Diane M, Zhou, Bin, Baldwin, H Scott, Turnbull, Daniel H

“…Gene targeting in the mouse has become a standard approach, yielding important new insights into the genetic factors underlying cardiovascular development and…”
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Histone macroH2A1 is concentrated in the inactive X chromosome of female preimplantation mouse embryos by Costanzi, C, Stein, P, Worrad, D M, Schultz, R M, Pehrson, J R

“…MacroH2As are core histone proteins with a hybrid structure consisting of a domain that closely resembles a full-length histone H2A followed by a large…”
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Regulation of gene expression in the mouse oocyte and early preimplantation embryo: developmental changes in Sp1 and TATA box-binding protein, TBP by WORRAD, D. M, RAM, P. T, SCHULTZ, R. M

“…We previously demonstrated that an Sp1-dependent reporter gene is preferentially expressed in G2 of the 1-cell mouse embryo following microinjection of the…”
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Temporally restricted spatial localization of acetylated isoforms of histone H4 and RNA polymerase II in the 2-cell mouse embryo by Worrad, D M, Turner, B M, Schultz, R M

“…Using immunofluorescent labeling and laser-scanning confocal microscopy, we show that isoforms of histone H4 acetylated on lysine 5, 8 and/or 12 (H4.Ac5-12),…”
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Stage-dependent redistributions of acetylated histones in nuclei of the early preimplantation mouse embryo by Stein, Paula, Worrad, Diane M., Belyaev, Nikolai D., Turner, Bryan M., Schultz, Richard M.

“…In the preimplantation mouse embryo, activation of the embryonic genome is accompanied by a transient enrichment of histone H4 acetylated at lysines 5, 8, and…”
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Regulation of gene expression in the preimplantation mouse embryo: Temporal and spatial patterns of expression of the transcription factor Sp1 by Worrad, Diane M., Schultz, Richard M.

“…Activation of the embryonic genome during preimplantation mouse development entails a dramatic reprogramming of the pattern of gene expression. The complement…”
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Role of chromatin structure in zygotic gene activation in the mammalian embryo by Schultz, Richard M., Worrad, Diane M.

“…Changes in chromatin structure, rather than changes in the activity of the transcriptional apparatus, may underlie the timing and basis for zygotic gene…”
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The herpes simplex virus type 2 UL3 open reading frame encodes a nuclear localizing phosphoprotein by Worrad, D M, Caradonna, S

“…The herpes simplex virus type 2 (HSV-2, strain 333) UL3 open reading frame (ORF) codes for a protein with a predicted molecular weight of 29,681. Comparisons…”
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