Search Results - "Wormsley, K G"

Oncogenes and onco-suppressor gene in adenocarcinoma of the oesophagus by Jankowski, J, Coghill, G, Hopwood, D, Wormsley, K G

“…While the activation of the proto-oncogenes has been implicated in the development and progression of cancer of many tissues, the role of oncogenes in the…”
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Review article: maintenance treatment with H2-receptor antagonists for peptic ulcer disease by Penston, J G, Wormsley, K G

“…In recent years a number of different strategies for managing patients with peptic ulcer disease have become available. The present review discusses the…”
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Increased expression of epidermal growth factor receptors in Barrett's esophagus associated with alkaline reflux: a putative model for carcinogenesis by Jankowski, J, Hopwood, D, Pringle, R, Wormsley, K G

“…A 49-yr-old male was reviewed who had a 10-yr history of reflux esophagitis. He presented initially with frequent heartburn of moderate severity and, on…”
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Proliferating cell nuclear antigen in oesophageal diseases; correlation with transforming growth factor alpha expression by Jankowski, J, McMenemin, R, Yu, C, Hopwood, D, Wormsley, K G

“…This study was designed to correlate mucosal proliferation in Barrett's oesophagus with expression of a growth promoting peptide, transforming growth factor…”
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Nine years of maintenance treatment with ranitidine for patients with duodenal ulcer disease by Penston, J G, Wormsley, K G

“…Four hundred and sixty-four patients with duodenal ulcer disease received continuous maintenance treatment with ranitidine for up to 9 years. Treatment failure…”
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Abnormal expression of growth regulatory factors in Barrett's oesophagus by Jankowski, J, McMenemin, R, Hopwood, D, Penston, J, Wormsley, K G

“…1. In order to assess potential abnormalities in the control of mucosal proliferation, 30 patients with Barrett's oesophagus were studied in order to evaluate…”
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Improved symptom relief and duodenal ulcer healing with lansoprazole, a new proton pump inhibitor, compared with ranitidine by Hawkey, C J, Long, R G, Bardhan, K D, Wormsley, K G, Cochran, K M, Christian, J, Moules, I K

“…The purpose of this study was to compare duodenal ulcer healing, symptom relief, and safety of lansoprazole (a new proton pump inhibitor) given at doses of 30…”
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Flow-cytometric analysis of growth-regulatory peptides and their receptors in Barrett's oesophagus and oesophageal adenocarcinoma by Jankowski, J, Hopwood, D, Wormsley, K G

“…The conventional assessment of the premalignant potential of Barrett's oesophagus is unsatisfactory. However, it has recently been shown that abnormalities of…”
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Epidermal growth factor in the oesophagus by Jankowski, J, Coghill, G, Tregaskis, B, Hopwood, D, Wormsley, K G

“…Epidermal growth factor (EGF) has been implicated in mitogenesis and oncogenesis in the gastrointestinal tract. To determine the role of EGF in oesophageal…”
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The administration of supplementary oxygen to prevent hypoxia during upper alimentary endoscopy by Block, R, Jankowski, J, Johnston, D, Colvin, J R, Wormsley, K G

“…A prospective, randomized, controlled trial was conducted in 200 consecutive patients undergoing endoscopy of the upper alimentary tract. One hundred patients…”
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Achlorhydria: hypergastrinaemia: carcinoids--a flawed hypothesis? by Penston, J, Wormsley, K G

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Rapid healing of gastric ulcers with lansoprazole by Bardhan, K D, Ahlberg, J, Hislop, W S, Lindholmer, C, Long, R G, Morgan, A G, Sjostedt, S, Smith, P M, Stig, R, Wormsley, K G

“…Lansoprazole is a new proton pump inhibitor which powerfully decreases acid secretion. We compared the efficacy and short-term safety of lansoprazole against…”
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Efficacy and safety of long-term maintenance therapy of duodenal ulcers by Penston, J, Wormsley, K G

“…The efficacy and safety of continuous (maintenance) treatment with ranitidine has been studied retrospectively in 388 patients with duodenal ulcer. The…”
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Mallory-Weiss tears occurring during endoscopy: a report of seven cases by Penston, J G, Boyd, E J, Wormsley, K G

“…Mallory-Weiss tears occurring during the course of upper gastrointestinal endoscopy are apparently rare. The present report describes seven cases of iatrogenic…”
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Trends in morbidity and mortality from peptic ulcer disease: Tayside versus Scotland by Penston, J G, Crombie, I K, Waugh, N R, Wormsley, K G

“…Recent studies have shown that the prophylactic use of H2-receptor antagonists reduces both ulcer recurrence and the risk of ulcer complications. Despite these…”
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Epidermal growth factor receptors in the oesophagus by Jankowski, J, Murphy, S, Coghill, G, Grant, A, Wormsley, K G, Sanders, D S, Kerr, M, Hopwood, D

“…The quantity and distribution of epidermal growth factor receptors (EGF-R) in oesophageal mucosa was studied in the oesophagus in order to determine its role…”
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Pentagastrin increases pepsin secretion without increasing its fractional synthetic rate by Corbett, M E, Boyd, E J, Penston, J G, Wormsley, K G, Watt, P W, Rennie, M J

“…We studied the effects of increasing doses of pentagastrin on gastric secretion of pepsin and on incorporation of L-[1-13C]leucine into gastric aspirate…”
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Assessing the safety of drugs for the long-term treatment of peptic ulcers by Wormsley, K G

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A placebo-controlled investigation of duodenal ulcer recurrence after withdrawal of long-term treatment with ranitidine by Penston, J G, Dixon, J S, Boyd, E J, Wormsley, K G

“…Ninety-two patients with duodenal ulcer disease, who had received long-term continuous treatment with ranitidine for an average of 7.5 years, participated in a…”
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Safety profile of ranitidine : a review by WORMSLEY, K. G

“…Ranitidine has been used for the treatment of millions of patients during the past 10 years. A small proportion of patients have developed a reaction to the…”
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