Search Results - "Worley, Michael"

Prediction of DNA Repair Inhibitor Response in Short-Term Patient-Derived Ovarian Cancer Organoids by Hill, Sarah J, Decker, Brennan, Roberts, Emma A, Horowitz, Neil S, Muto, Michael G, Worley, Jr, Michael J, Feltmate, Colleen M, Nucci, Marisa R, Swisher, Elizabeth M, Nguyen, Huy, Yang, Chunyu, Morizane, Ryuji, Kochupurakkal, Bose S, Do, Khanh T, Konstantinopoulos, Panagiotis A, Liu, Joyce F, Bonventre, Joseph V, Matulonis, Ursula A, Shapiro, Geoffrey I, Berkowitz, Ross S, Crum, Christopher P, D'Andrea, Alan D

“…Based on genomic analysis, 50% of high-grade serous ovarian cancers (HGSC) are predicted to have DNA repair defects. Whether this substantial subset of HGSCs…”
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Endometriosis-associated ovarian cancer: a review of pathogenesis by Worley, Michael J, Welch, William R, Berkowitz, Ross S, Ng, Shu-Wing

“…Endometriosis is classically defined as the presence of endometrial glands and stroma outside of the endometrial lining and uterine musculature. With an…”
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Enhanced Efficacy of Simultaneous PD-1 and PD-L1 Immune Checkpoint Blockade in High-Grade Serous Ovarian Cancer by Wan, Changxin, Keany, Matthew P, Dong, Han, Al-Alem, Linah F, Pandya, Unnati M, Lazo, Suzan, Boehnke, Karsten, Lynch, Katherine N, Xu, Rui, Zarrella, Dominique T, Gu, Shengqing, Cejas, Paloma, Lim, Klothilda, Long, Henry W, Elias, Kevin M, Horowitz, Neil S, Feltmate, Colleen M, Muto, Michael G, Worley, Jr, Michael J, Berkowitz, Ross S, Matulonis, Ursula A, Nucci, Marisa R, Crum, Christopher P, Rueda, Bo R, Brown, Myles, Liu, Xiaole Shirley, Hill, Sarah J

“…Immune therapies have had limited efficacy in high-grade serous ovarian cancer (HGSC), as the cellular targets and mechanism(s) of action of these agents in…”
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Gynecologic oncology treatment modifications or delays in response to the COVID-19 pandemic in a publicly funded versus privately funded North American tertiary cancer center by Piedimonte, Sabrina, Li, Sue, Laframboise, Stephane, Ferguson, Sarah E., Bernardini, Marcus Q., Bouchard-Fortier, Genevieve, Hogen, Liat, Cybulska, Paulina, Worley, Michael J., May, Taymaa

“…To compare gynecologic oncology surgical treatment modifications and delays during the first wave of the COVID-19 pandemic between a publicly funded Canadian…”
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Salpingectomy for the Primary Prevention of Ovarian Cancer: A Systematic Review by Kahn, Ryan M, Gordhandas, Sushmita, Godwin, Kendra, Stone, Rebecca L, Worley, Jr, Michael J, Lu, Karen H, Long Roche, Kara C

“…Most ovarian cancers originate in the fimbriated end of the fallopian tube. This has led to the hypothesis that surgical resection of the fallopian tubes at…”
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Losartan treatment enhances chemotherapy efficacy and reduces ascites in ovarian cancer models by normalizing the tumor stroma by Zhao, Yanxia, Cao, Jinghong, Melamed, Alexander, Worley, Michael, Gockley, Allison, Jones, Dennis, Nia, Hadi T., Zhang, Yanling, Stylianopoulos, Triantafyllos, Kumar, Ashwin S., Mpekris, Fotios, Datta, Meenal, Sun, Yao, Wu, Limeng, Gao, Xing, Yeku, Oladapo, del Carmen, Marcela G., Spriggs, David R., Jain, Rakesh K., Xu, Lei

“…In ovarian cancer patients, tumor fibrosis and angiotensin-driven fibrogenic signaling have been shown to inversely correlate with survival. We sought to…”
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Dysregulated microRNAs in the pathogenesis and progression of cervical neoplasm by Cheung, Tak-hong, Man, Kwun-nok Mimi, Yu, Mei-yung, Yim, So-fan, Siu, Nelson S.S., Lo, Keith W.K., Doran, Graeme, Wong, Raymond R.Y., Wang, Vivian W., Smith, David I., Worley Jr, Michael J., Berkowitz, Ross S., Chung, Tony K.H., Wong, Yick-fu

“…MicroRNAs (miRNAs) play an important role in a variety of physiological as well as pathophysiological processes, including carcinogenesis. The aim of this…”
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Risk of venous thromboembolism for ovarian cancer patients during first-line therapy after implementation of an Enhanced Recovery After Surgery (ERAS) protocol by Li, Sue, Bercow, Alexandra S., Falzone, Michele, Kalyanaraman, Rajeshwari, Worley, Michael J., Feltmate, Colleen M., Pelletier, Andrea, Elias, Kevin M.

“…To determine incidence and risk factors for VTE for patients with advanced epithelial ovarian cancer undergoing first-line therapy, including cytoreductive…”
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Fragmentation of surgery and chemotherapy in the initial phase of ovarian cancer care and its association with overall survival by Cham, Stephanie, Huang, Yongmei, Melamed, Alexander, Worley, Michael J., Hou, June Y., Tergas, Ana I., Khoury-Collado, Fady, Gockley, Allison, Clair, Caryn M.S.T., Hershman, Dawn L., Wright, Jason D.

“…Fragmentation occurs when a patient receives care at more than one hospital, and the long-term effects in ovarian cancer are unknown. We examined the…”
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Racial disparities in brachytherapy administration and survival in women with locally advanced cervical cancer by Alimena, Stephanie, Yang, David D, Melamed, Alexander, Mahal, Brandon A, Worley, Michael J, Feldman, Sarah, Elias, Kevin M, Orio, Peter F, Lee, Larissa J, King, Martin

“…AbstractObjectiveBlack women have the highest incidence and mortality from cervical cancer in the United States. This study evaluated whether racial…”
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A novel classification of residual disease after interval debulking surgery for advanced-stage ovarian cancer to better distinguish oncologic outcome by Manning-Geist, Beryl L., Hicks-Courant, Katherine, Gockley, Allison A., Clark, Rachel M., Del Carmen, Marcela G., Growdon, Whitfield B., Horowitz, Neil S., Berkowitz, Ross S., Muto, Michael G., Worley, Michael J.

“…Complete surgical resection affords the best prognosis at the time of interval debulking surgery. When complete surgical resection is unachievable, optimal…”
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Disease Distribution at Presentation Impacts Benefit of IP Chemotherapy Among Patients with Advanced-Stage Ovarian Cancer by Manning-Geist, Beryl L., Sullivan, Mackenzie W., Sarda, Vishnudas, Gockley, Allison A., del Carmen, Marcela G., Matulonis, Ursula, Growdon, Whitfield B., Horowitz, Neil S., Berkowitz, Ross S., Clark, Rachel M., Worley, Michael J.

“…Background Ovarian cancer with miliary disease spread is an aggressive phenotype lacking targeted management strategies. We sought to determine whether…”
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Liquid biopsy of HPV DNA in cervical cancer by Cheung, Tak Hong, Yim, So Fan, Yu, Mei Yun, Worley, Michael J., Fiascone, Stephen J., Chiu, Rossa W.K., Lo, Keith W.K., Siu, Nelson S.S., Wong, Martin C.S., Yeung, Apple C.M., Wong, Raymond R.Y., Chen, Zi Gui, Elias, Kevin M., Chung, Tony K.H., Berkowitz, Ross S., Wong, Yick Fu, Chan, Paul K.S.

“…•First study to explore droplet digital PCR for HPV-associated E7 and L1 in plasma of patients with cervical cancer.•Presence of such plasma-based viral gene…”
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Impact of residual disease at interval debulking surgery on platinum resistance and patterns of recurrence for advanced-stage ovarian cancer by Greer, Anna, Gockley, Allison, Manning-Geist, Beryl, Melamed, Alexander, Sisodia, Rachel Clark, Berkowitz, Ross, Horowitz, Neil, Del Carmen, Marcela, Growdon, Whitfield B, Worley, Jr, Michael

“…To evaluate the impact of size and distribution of residual disease after interval debulking surgery on the timing and patterns of recurrence for patients with…”
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Same-Day Discharge After Laparoscopic Hysterectomy for Endometrial Cancer by Melamed, Alexander, Katz Eriksen, Jennifer L., Hinchcliff, Emily M., Worley, Michael J., Berkowitz, Ross S., Horowitz, Neil S., Muto, Michael G., Urman, Richard D., Feltmate, Colleen M.

“…Purpose The aim of this study was to investigate the relationship between same-day discharge (SDD) and postoperative complications within 30 days of…”
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Moving beyond “complete surgical resection” and “optimal”: Is low-volume residual disease another option for primary debulking surgery? by Manning-Geist, Beryl L., Hicks-Courant, Katherine, Gockley, Allison A., Clark, Rachel M., del Carmen, Marcela G., Growdon, Whitfield B., Horowitz, Neil S., Berkowitz, Ross S., Muto, Michael G., Worley, Michael J.

“…To examine the relationship between volume of residual disease and oncologic outcomes among patients with advanced-stage epithelial ovarian/fallopian…”
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Neoadjuvant chemotherapy does not disproportionately influence post-operative complication rates or time to chemotherapy in obese patients with advanced-stage ovarian cancer by Kanbergs, Alexa N., Manning-Geist, Beryl L., Pelletier, Andrea, Sullivan, Mackenzie W., del Carmen, Marcela G., Horowitz, Neil S., Growdon, Whitfield B., Clark, Rachel M., Muto, Michael G., Worley, Michael J.

“…To determine whether neoadjuvant chemotherapy (NACT) disproportionately benefits obese patients. Data were collected from stage IIIC-IV ovarian cancer patients…”
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Infection, thrombosis, and oncologic outcome after interval debulking surgery: Does perioperative blood transfusion matter? by Manning-Geist, Beryl L., Alimena, Stephanie, del Carmen, Marcela G., Goodman, Annekathryn, Clark, Rachel M., Growdon, Whitfield B., Horowitz, Neil S., Berkowitz, Ross S., Muto, Michael G., Worley, Michael J.

“…To determine whether perioperative red blood cell transfusion (PRBCT) affects infection, thrombosis, or survival rates in epithelial ovarian cancer (EOC)…”
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Trends in Place of Death Among Patients With Gynecologic Cancer in the United States by Hicks-Courant, Katherine, Melamed, Alexander, Worley, Michael J., Kim, Young Bae, Schorge, John O., Rauh-Hain, J. Alejandro

“…OBJECTIVE:To describe the change over time in place of death (hospital, home, hospice) among all women in the United States who died of gynecologic…”
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Durable remission for a woman with refractory choriocarcinoma treated with anti-endoglin monoclonal antibody and bevacizumab: A case from the New England Trophoblastic Disease Center, Brigham and Women's Hospital and Dana-Farber Cancer Institute by Worley, Michael J., Elias, Kevin M., Horowitz, Neil S., Quade, Bradley J., Berkowitz, Ross S.

“…A 36-year-old with metastatic and refractory choriocarcinoma following single- and multi-agent chemotherapy and surgical metastectomy experienced a durable…”
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