Search Results - "Workman, L."

Histone exchange, chromatin structure and the regulation of transcription by Venkatesh, Swaminathan, Workman, Jerry L.

“…Key Points Histone exchange involves the partial or complete exchange of nucleosomes for newer or altered components. This process occurs sequentially through…”
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Signals and Combinatorial Functions of Histone Modifications by Suganuma, Tamaki, Workman, Jerry L

“…Alterations of chromatin structure have been shown to be crucial for response to cell signaling and for programmed gene expression in development…”
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Transcription-associated histone modifications and cryptic transcription by Smolle, Michaela, Workman, Jerry L.

“…Eukaryotic genomes are packaged into chromatin, a highly organized structure consisting of DNA and histone proteins. All nuclear processes take place in the…”
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Diverse Activities of Histone Acylations Connect Metabolism to Chromatin Function by Dutta, Arnob, Abmayr, Susan M., Workman, Jerry L.

“…Modifications of histones play important roles in balancing transcriptional output. The discovery of acyl marks, besides histone acetylation, has added to the…”
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Histone acetyltransferase complexes: one size doesn't fit all by Workman, Jerry L, Lee, Kenneth K

“…Over the past 10 years, the study of histone acetyltransferases (HATs) has advanced significantly, and a number of HATs have been isolated from various…”
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Readers of histone modifications by Yun, Miyong, Wu, Jun, Workman, Jerry L, Li, Bing

“…Histone modifications not only play important roles in regulating chromatin structure and nuclear processes but also can be passed to daughter cells as…”
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The Role of Chromatin during Transcription by Li, Bing, Carey, Michael, Workman, Jerry L.

“…Chromatin structure imposes significant obstacles on all aspects of transcription that are mediated by RNA polymerase II. The dynamics of chromatin structure…”
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Nucleosome remodeling and epigenetics by Becker, Peter B, Workman, Jerry L

“…Eukaryotic chromatin is kept flexible and dynamic to respond to environmental, metabolic, and developmental cues through the action of a family of so-called…”
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The SAGA chromatin-modifying complex: the sum of its parts is greater than the whole by Soffers, Jelly H M, Workman, Jerry L

“…There are many large protein complexes involved in transcription in a chromatin context. However, recent studies on the SAGA coactivator complex are generating…”
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Crosstalk among Histone Modifications by Suganuma, Tamaki, Workman, Jerry L.

“…Histone modifications play a complex role in the regulation of transcription. Recent studies ( Duncan et al., 2008; Lee et al., 2007; Li et al., 2008) reveal…”
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The changing faces of HP1: From heterochromatin formation and gene silencing to euchromatic gene expression by Kwon, So Hee, Workman, Jerry L.

“…Heterochromatin protein 1 (HP1) is a positive regulator of active transcription in euchromatin. HP1 was first identified in Drosophila melanogaster as a major…”
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Light at night increases body mass by shifting the time of food intake by Fonken, Laura K., Workman, Joanna L., Walton, James C., Weil, Zachary M., Morris, John S., Haim, Abraham, Nelson, Randy J., Denlinger, David L.

“…The global increase in the prevalence of obesity and metabolic disorders coincides with the increase of exposure to light at night (LAN) and shift work…”
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Selective suppression of antisense transcription by Set2-mediated H3K36 methylation by Venkatesh, Swaminathan, Li, Hua, Gogol, Madelaine M., Workman, Jerry L.

“…Maintenance of a regular chromatin structure over the coding regions of genes occurs co-transcriptionally via the ‘chromatin resetting’ pathway. One of the…”
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Serine and SAM Responsive Complex SESAME Regulates Histone Modification Crosstalk by Sensing Cellular Metabolism by Li, Shanshan, Swanson, Selene K., Gogol, Madelaine, Florens, Laurence, Washburn, Michael P., Workman, Jerry L., Suganuma, Tamaki

“…Pyruvate kinase M2 (PKM2) is a key enzyme for glycolysis and catalyzes the conversion of phosphoenolpyruvate (PEP) to pyruvate, which supplies cellular energy…”
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Set2 methylation of histone H3 lysine 36 suppresses histone exchange on transcribed genes by Venkatesh, Swaminathan, Smolle, Michaela, Li, Hua, Gogol, Madelaine M., Saint, Malika, Kumar, Shambhu, Natarajan, Krishnamurthy, Workman, Jerry L.

“…In yeast, histone H3 lysine 36 methylation can suppress the incorporation of acetylated histones by inhibiting histone exchange in transcribed genes, thus…”
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ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth by Atanassov, Boyko S., Mohan, Ryan D., Lan, Xianjiang, Kuang, Xianghong, Lu, Yue, Lin, Kevin, McIvor, Elizabeth, Li, Wenqian, Zhang, Ying, Florens, Laurence, Byrum, Stephanie D., Mackintosh, Samuel G., Calhoun-Davis, Tammy, Koutelou, Evangelia, Wang, Li, Tang, Dean G., Tackett, Alan J., Washburn, Michael P., Workman, Jerry L., Dent, Sharon Y.R.

“…Histone H2B monoubiquitination (H2Bub1) is centrally involved in gene regulation. The deubiquitination module (DUBm) of the SAGA complex is a major regulator…”
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Chromatin remodelers Isw1 and Chd1 maintain chromatin structure during transcription by preventing histone exchange by Smolle, Michaela, Venkatesh, Swaminathan, Gogol, Madelaine M, Li, Hua, Zhang, Ying, Florens, Laurence, Washburn, Michael P, Workman, Jerry L

“…The histone H3K36 methylation mark is associated with coding regions of actively transcribed genes, yet it plays a negative role during transcription…”
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Masculinity Contest Cultures in Policing Organizations and Recommendations for Training Interventions by Rawski, Shannon L., Workman‐Stark, Angela L.

“…In the wake of the #BlackLivesMatter and #MeToo movements, police conduct has been increasingly scrutinized by the public, especially the use of excessive…”
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The methyltransferase SETD2 couples transcription and splicing by engaging mRNA processing factors through its SHI domain by Bhattacharya, Saikat, Levy, Michaella J., Zhang, Ning, Li, Hua, Florens, Laurence, Washburn, Michael P., Workman, Jerry L.

“…Heterogeneous ribonucleoproteins (hnRNPs) are RNA binding molecules that are involved in key processes such as RNA splicing and transcription. One such hnRNP…”
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3D cell bioprinting of self-assembling peptide-based hydrogels by Raphael, Bella, Khalil, Tony, Workman, Victoria L., Smith, Andrew, Brown, Cameron P., Streuli, Charles, Saiani, Alberto, Domingos, Marco

“…•Novel methodology for 3D cell printing of self-assembly peptide-based hydrogels.•3D constructs with variable stiffness and good structural integrity are…”
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