Search Results - "Workman, Julie"

Preclinical evaluation of the CDK4/6 inhibitor palbociclib in combination with a PI3K or MEK inhibitor in colorectal cancer by Lee, Cha Len, Cremona, Mattia, Farrelly, Angela, Workman, Julie A., Kennedy, Sean, Aslam, Razia, Carr, Aoife, Madden, Stephen, O'Neill, Brian, Hennessy, Bryan T., Toomey, Sinead

“…Studies have demonstrated the efficacy of Palbociclib (CDK 4/6 inhibitor), Gedatolisib (PI3K/mTOR dual inhibitor) and PD0325901 (MEK1/2 inhibitor) in…”
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Targeting the PI3K and MAPK pathways to improve response to HER2-targeted therapies in HER2-positive gastric cancer by Mezynski, M Janusz, Farrelly, Angela M, Cremona, Mattia, Carr, Aoife, Morgan, Clare, Workman, Julie, Armstrong, Paul, McAuley, Jennifer, Madden, Stephen, Fay, Joanna, Sheehan, Katherine M, Kay, Elaine W, Holohan, Ciara, Elamin, Yasir, Rafee, Shereen, Morris, Patrick G, Breathnach, Oscar, Grogan, Liam, Hennessy, Bryan T, Toomey, Sinead

“…Aberrant PI3K signalling is implicated in trastuzumab resistance in HER2-positive gastric cancer (GC). The role of PI3K or MEK inhibitors in sensitising…”
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Classifying Whiplash Recovery Status Using the Neck Disability Index: Optimized Cutoff Points Derived From Receiver Operating Characteristic by Croft, Arthur C., Workman, Julie A., Szatalowicz, Michael P., Roberts, Philip E., Suiter, Leonard R.

“…Researchers often use Neck Disability Index (NDI) scores to classify recovery status in whiplash patients. The purpose of this study was to investigate the…”
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Preclinical drug testing for clinical trial planning of novel combinative therapy with PI3K and MAPK inhibitors in colorectal cancer(CRC) by Lee, Cha Len, Toomey, Sinead, Cremona, Mattia, Workman, Julie A., Hennessy, Bryan

“…Abstract only 179 Background: Combinative inhibitors with multiple actions to target downstream effectors are good strategy to reduce resistance occurrence…”
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How does Disproportionality in Discipline Manifest in Rural Schools in Southeast Arkansas? by Workman, Julie

“…African American students are disciplined in schools at disproportionately higher rates than White students. This trend was first reported in 1975 in a report…”
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Exhaled Breath Condensate (EBC) analysis of circulating tumour DNA (ctDNA) using a lung cancer specific UltraSEEK oncogene panel by Ryan, Daniel J., Toomey, Sinead, Smyth, Robert, Madden, Stephen F., Workman, Julie, Cummins, Robert, Sheehan, Katherine, Fay, Joanna, Naidoo, Jarushka, Breathnach, Oscar S., Morris, Patrick G., Grogan, Liam, O'Brien, Michael E., Sulaiman, Imran, Hennessy, Bryan T., Morgan, Ross K.

“…•Exhaled Breath (EBC) and plasma were analysed for 5 genetic alterations using ultrasensitive PCR in lung cancer patients.•Results were compared to…”
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