Search Results - "Worgul, T J"

Suppression of residual oestrogen production with aminoglutethimide in women following surgical hypophysectomy or adrenalectomy by Samojlik, E, Santen, R J, Worgul, T J

“…In postmenopausal women with breast carcinoma, plasma and urinary oestrogens remain detectable following surgical adrenalectomy or hypophysectomy. These…”
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Clinical effect of aminoglutethimide, medical adrenalectomy, in treatment of 43 patients with advanced prostatic carcinoma by Drago, J R, Santen, R J, Lipton, A, Worgul, T J, Harvey, H A, Boucher, A, Manni, A, Rohner, T J

“…The initial treatment of patients with Stage D prostatic carcinoma with orchiectomy or estrogens is successful in giving objective and subjective improvement…”
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Evidence that brain aromatization regulates LH secretion in the male dog by Worgul, T J, Santen, R J, Samojlik, E, Irwin, G, Falvo, R E

“…A variety of data suggest an independent role for androgens and estrogens in the regulation of luteinizing hormone (LH) secretion in the male. Estrogens, in…”
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Clinical and biochemical effect of aminoglutethimide in the treatment of advanced prostatic carcinoma by Worgul, T J, Santen, R J, Samojlik, E, Veldhuis, J D, Lipton, A, Harvey, H A, Drago, J R, Rohner, T J

“…Treatment of male patients with advanced prostatic carcinoma and disease progression after initial endocrine therapy frequently is unsatisfactory. However,…”
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How effective is surgical adrenalectomy in lowering steroid hormone concentrations? by Worgul, T J, Santen, R J, Samojlik, E, Wells, S A

“…Surgical adrenalectomy produces objective tumour regression in 50-60% of estrogen receptor-positive women with metastatic breast carcinoma. Additional…”
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Adequacy of estrogen suppression with aminoglutethimide and hydrocortisone as treatment of human breast cancer: correlation of hormonal data with clinical responses by Santen, R J, Worgul, T J, Samojlik, E, Boucher, A E, Lipton, A, Harvey, H

“…Human breast neoplasms can be divided into hormone-dependent and hormone-independent subtypes. Estrogen is the major hormonal stimulus for growth of the…”
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Aminoglutethimide as treatment of postmenopausal women with advanced breast carcinoma by Santen, R J, Worgul, T J, Lipton, A, Harvey, H, Boucher, A, Samojlik, E, Wells, S A

“…Hormone-dependent breast carcinomas respond to deprivation of biologically active estrogens with objectively quantifiable tumor regression. Aminoglutethimide,…”
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A possible role of endogenous opioids in the control of prolactin and luteinizing-hormone secretion in the human by Veldhuis, J D, Worgul, T J, Monsaert, R, Hammond, J M

“…We investigated the participation by endogenous opioid peptides in the control of prolactin and gonadotropin secretion in 5 normal men and 6 normal women, and…”
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Comparison of surgical adrenalectomy to medical adrenalectomy in patients with metastatic carcinoma of the breast by Wells, Jr, S A, Worgul, T J, Samojlik, E, Boucher, A E, Lipton, A, Harvey, H, White, D, Smart, E, Cox, C, Santen, R J

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Effect of very high dose D-leucine6-gonadotropin-releasing hormone proethylamide on the hypothalamic-pituitary testicular axis in patients with prostatic cancer by Warner, B, Worgul, T J, Drago, J, Demers, L, Dufau, M, Max, D, Santen, R J

“…Potent synthetic analogs of gonadotropin-releasing hormone produce parodoxical antireproductive effects when administered chronically. These compounds are…”
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A randomized trial comparing surgical adrenalectomy with aminoglutethimide plus hydrocortisone in women with advanced breast cancer by Santen, R J, Worgul, T J, Samojlik, E, Interrante, A, Boucher, A E, Lipton, A, Harvey, H A, White, D S, Smart, E, Cox, C, Wells, S A

“…We randomized 96 postmenopausal women with metastatic breast carcinoma to receive surgical adrenalectomy or medical therapy with an adrenal inhibitor,…”
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Evaluation of methods for perfusing rat testes by Baker, H W, Bailey, D J, Worgul, T J, Jefferson, L S, Santen, R J, Bardin, C W

“…Organ perfusion methods offer a number of advantages in biologic studies but require full characterization before application. Two new methods for perfusing…”
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Plasma estrone-sulfate: assessment of reduced estrogen production during treatment of metastatic breast carcinoma by Samojlik, E, Santen, R J, Worgul, T J

“…Highly sensitive and specific estrogen assays are required to monitor the hormonal effects of surgical adrenalectomy or pharmacologic estrogen suppression in…”
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Recovery of hypothalamic-pituitary-adrenal function after long term suppression by aminoglutethimide and hydrocortisone by Worgul, T J, Kendall, J, Santen, R J

“…Little data are available concerning recovery of adrenal function after prolonged inhibition of steroidogenesis by enzyme inhibitors. Aminoglutethimide (AG), a…”
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Triple drug chemotherapy in treatment of prostate adenocarcinoma Nb Pr A.I.-III by Drago, J R, Worgul, T J

“…The combination of cyclophosphamide, cis-platinum, and adriamycin has been evaluated in the Nb tumor model system. Triple drug therapy has resulted in marked…”
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Castration--chemotherapy treatment of prostate cancer model by Drago, J R, Worgul, T J, Gallagher, C

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Prolactin-secreting pituitary adenomas. Association with multiple endocrine neoplasia, type I by Veldhuis, J D, Green, 3rd, J E, Kovacs, E, Worgul, T J, Murray, F T, Hammond, J M

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