Search Results - "Worden, J"
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Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L
Published in Cell (07-03-2019)“…Methylation of histone H3 K79 by Dot1L is a hallmark of actively transcribed genes that depends on monoubiquitination of H2B K120 (H2B-Ub) and is an example of…”
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An AAA Motor-Driven Mechanical Switch in Rpn11 Controls Deubiquitination at the 26S Proteasome
Published in Molecular cell (07-09-2017)“…Poly-ubiquitin chains direct protein substrates to the 26S proteasome, where they are removed by the deubiquitinase Rpn11 during ATP-dependent substrate…”
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Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome
Published in eLife (10-01-2020)“…Methylation of histone H3K4 is a hallmark of actively transcribed genes that depends on mono-ubiquitination of histone H2B (H2B-Ub). H3K4 methylation in yeast…”
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Structure of the Rpn11–Rpn8 dimer reveals mechanisms of substrate deubiquitination during proteasomal degradation
Published in Nature structural & molecular biology (01-03-2014)“…Rpn11, the only essential deubiquitinase (DUB) of the 26S proteasome, sits at the top of the substrate entry pathway and facilitates substrate degradation…”
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Reconstitution of the 26S proteasome reveals functional asymmetries in its AAA+ unfoldase
Published in Nature structural & molecular biology (01-10-2013)“…In the eukaryotic 26S proteasome, a heterohexameric AAA+ complex unfolds substrates prior to degradation. The yeast unfoldase subunits have now been expressed…”
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Characterization of ozone profiles derived from Aura TES and OMI radiances
Published in Atmospheric chemistry and physics (26-03-2013)“…We present satellite based ozone profile estimates derived by combining radiances measured at thermal infrared (TIR) wavelengths from the Aura Tropospheric…”
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The Atmospheric Infrared Sounder version 6 cloud products
Published in Atmospheric chemistry and physics (10-01-2014)“…The version 6 cloud products of the Atmospheric Infrared Sounder (AIRS) and Advanced Microwave Sounding Unit (AMSU) instrument suite are described. The cloud…”
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Decadal record of satellite carbon monoxide observations
Published in Atmospheric chemistry and physics (22-01-2013)“…Atmospheric carbon monoxide (CO) distributions are controlled by anthropogenic emissions, biomass burning, transport and oxidation by reaction with the…”
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Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition
Published in eLife (08-01-2016)“…The 26S proteasome is responsible for the selective, ATP-dependent degradation of polyubiquitinated cellular proteins. Removal of ubiquitin chains from…”
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Spatially resolving methane emissions in California: constraints from the CalNex aircraft campaign and from present (GOSAT, TES) and future (TROPOMI, geostationary) satellite observations
Published in Atmospheric chemistry and physics (14-08-2014)“…We apply a continental-scale inverse modeling system for North America based on the GEOS-Chem model to optimize California methane emissions at 1/2° × 2/3°…”
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Profiles of CH4, HDO, H2O, and N2O with improved lower tropospheric vertical resolution from Aura TES radiances
Published in Atmospheric measurement techniques (01-02-2012)“…Thermal infrared (IR) radiances measured near 8 microns contain information about the vertical distribution of water vapor (H2 O), the water isotopologue HDO,…”
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Regional data assimilation of multi-spectral MOPITT observations of CO over North America
Published in Atmospheric chemistry and physics (19-06-2015)“…Chemical transport models (CTMs) driven with high-resolution meteorological fields can better resolve small-scale processes, such as frontal lifting or deep…”
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Validation of TES methane with HIPPO aircraft observations: implications for inverse modeling of methane sources
Published in Atmospheric chemistry and physics (17-02-2012)“…We validate satellite methane observations from the Tropospheric Emission Spectrometer (TES) with 151 aircraft vertical profiles over the Pacific from the…”
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Transpacific transport of ozone pollution and the effect of recent Asian emission increases on air quality in North America: an integrated analysis using satellite, aircraft, ozonesonde, and surface observations
Published in Atmospheric chemistry and physics (01-01-2008)“…We use an ensemble of aircraft, satellite, sonde, and surface observations for April–May 2006 (NASA/INTEX-B aircraft campaign) to better understand the…”
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Impacts of midlatitude precursor emissions and local photochemistry on ozone abundances in the Arctic
Published in Journal of Geophysical Research: Atmospheres (16-01-2012)“…We assess the impact of transport of pollution from midlatitudes on the abundance of ozone in the Arctic in summer 2006 using the GEOS‐Chem global chemical…”
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Thunderstorms and upper troposphere chemistry during the early stages of the 2006 North American Monsoon
Published in Atmospheric chemistry and physics (21-11-2012)“…To study the meteorology and chemistry that is associated with the early stages of the North American Monsoon, the Weather Research and Forecasting model…”
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Grief counseling and grief therapy: a handbook for the mental health practitioner
Published 01-08-2008“…Dr. Worden presents the highly anticipated fourth edition to Grief Counseling and Grief Therapy, the gold standard of grief therapy handbooks. The previous…”
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Constraints on Asian ozone using Aura TES, OMI and Terra MOPITT
Published in Atmospheric chemistry and physics (08-01-2015)“…Rapid industrialization in Asia in the last two decades has resulted in a significant increase in Asian ozone (O3) precursor emissions with likely a…”
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The influence of boreal biomass burning emissions on the distribution of tropospheric ozone over North America and the North Atlantic during 2010
Published in Atmospheric chemistry and physics (21-02-2012)“…We have analysed the sensitivity of the tropospheric ozone distribution over North America and the North Atlantic to boreal biomass burning emissions during…”
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Evaluation of ACCMIP Outgoing Longwave Radiation from Tropospheric Ozone Using TES Satellite Observations
Published in Atmospheric chemistry and physics (18-04-2013)“…We use simultaneous observations of tropospheric ozone and outgoing longwave radiation (OLR) sensitivity to tropospheric ozone from the Tropospheric Emission…”
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