Search Results - "Wooten, G. F."

Are men at greater risk for Parkinson’s disease than women? by Wooten, G F, Currie, L J, Bovbjerg, V E, Lee, J K, Patrie, J

“…Parkinson’s disease seems to occur more commonly in men than women based primarily on studies of death rates and prevalence. In recent years, several…”
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Prospective study of hallucinations and delusions in Parkinson's disease by Holroyd, S, Currie, L, Wooten, G F

“…OBJECTIVE This study was undertaken to determine the prevalence of hallucinations and delusions in Parkinson's disease, to describe such symptoms…”
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Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD by NUTT, J. G, BURCHIEL, K. J, WOOTEN, G. F, COMELLA, C. L, JANKOVIC, J, LANG, A. E, LAWS, E. R, LOZANO, A. M, PENN, R. D, SIMPSON, R. K, STACY, M

“…To assess the safety, tolerability, and biological activity of glial cell line-derived neurotrophic factor (GDNF) administered by an implanted…”
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The effect of Parkinson's disease on interference control during action selection by Wylie, S.A., van den Wildenberg, W.P.M., Ridderinkhof, K.R., Bashore, T.R., Powell, V.D., Manning, C.A., Wooten, G.F.

“…Basal ganglia structures comprise a portion of the neural circuitry that is hypothesized to coordinate the selection and suppression of competing responses…”
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The effect of speed-accuracy strategy on response interference control in Parkinson's disease by Wylie, S.A., van den Wildenberg, W.P.M., Ridderinkhof, K.R., Bashore, T.R., Powell, V.D., Manning, C.A., Wooten, G.F.

“…Studies that used conflict paradigms such as the Eriksen Flanker task show that many individuals with Parkinson's disease (PD) have pronounced difficulty…”
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Optimizing the ongoing search for new treatments for parkinson disease : Using futility designs by TILLEY, B. C, PALESCH, Y. Y, KIEBURTZ, K, RAVINA, B, HUANG, P, ELM, J. J, SHANNON, K, WOOTEN, G. F, TANNER, C. M, GOETZ, G. C

“…Many agents are being considered for treatment of Parkinson disease (PD). Given the large number of agents and the limited resources to evaluate new agents, it…”
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BDNF genetic variants are associated with onset age of familial Parkinson disease : GenePD Study by KARAMOHAMED, S, LATOURELLE, J. C, GUTTMAN, M, NICHOLSON, G, WILK, J. B, SAINT-HILAIRE, M, DESTEFANO, A. L, PRAKASH, R, TOBIN, S, WILLIAMSON, J, SUCHOWERSKY, O, LABELL, N, RACETTE, B. A, GROWDON, B. N. J, SINGER, C, WATTS, R, GOLDWURM, S, PEZZOLI, G, BAKER, K. B, GIROUX, M. L, PRAMSTALLER, P. P, BURN, D. J, CHINNERY, P, PERLMUTTER, J. S, SHERMAN, S, VIEREGGE, P, LITVAN, I, GUSELLA, J. F, MYERS, R. H, PARSIAN, A, WOOTEN, G. F, LEW, M, KLEIN, C, SHILL, H, GOLBE, L. I, MARK, M. H

“…Brain-derived neurotrophic factor (BDNF) stimulates neuronal growth and protects nigral dopamine neurons in animal models of Parkinson disease (PD). Therefore,…”
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Agonists vs levodopa in PD: the thrilla of whitha by Wooten, G F

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Autosomal dominant subcortical gliosis presenting as frontotemporal dementia by SWERDLOW, R. H, MILLER, B. B, LOPES, M. B. S, MANDELL, J. W, WOOTEN, G. F, DAMGAARD, P, MANNING, C, FOWLER, M, BRASHEAR, H. R

“…To describe a multigenerational kindred with a frontotemporal dementia clinical syndrome (FTDS), extensive subcortical gliosis pathology, and autosomal…”
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Herbicide exposure modifies GSTP1 haplotype association to parkinson onset age : The GenePD study by WILK, J. B, TOBIN, J. E, SINGER, C, GROWDON, J. H, LATOURELLE, J. C, SAINT-HILAIRE, M. H, DESTEFANO, A. L, PRAKASH, R, WILLIAMSON, S, BERG, C. J, SUN, M, GOLDWURM, S, SUCHOWERSKY, O, PEZZOLI, G, RACETTE, B. A, PERLMUTTER, J. S, PARSIAN, A, BAKER, K. B, GIROUX, M. L, LITVAN, I, PRAMSTALLER, P. P, NICHOLSON, G, BURN, D. J, SHILL, H. A, CHINNERY, P. F, VIEREGGE, P, SLEVIN, J. T, CAMBI, F, MACDONALD, M. E, GUSELLA, J. F, MYERS, R. H, GOLBE, L. I, KLEIN, C, WOOTEN, G. F, LEW, M. F, MARK, M. H, GUTTMAN, M, WATTS, R. L

“…Polymorphisms in the glutathione S-transferase pi gene (GSTP1), encoding GSTP1-1, a detoxification enzyme, may increase the risk of Parkinson disease (PD) with…”
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A haplotype at the PARK3 locus influences onset age for Parkinson's disease: The GenePD study by KARAMOHAMED, S, DESTEFANO, A. L, CURRIE, L. J, WOOTEN, G. F, STACY, M, SAINT-HILAIRE, M, FELDMAN, R. G, SULLIVAN, K. M, XU, G, WATTS, R, GROWDON, J, LEW, M, WILK, J. B, WATERS, C, VIEREGGE, P, PRAMSTALLER, P. P, KLEIN, C, RACETTE, B. A, PERLMUTTER, J. S, PARSIAN, A, SINGER, C, MONTGOMERY, E, BAKER, K, SHOEMAKER, C. M, GUSELLA, J. F, FINK, S. J, MYERS, R. H, HERBERT, A, GOLBE, L. I, MARK, M. H, LAZZARINI, A. M, SUCHOWERSKY, O, LABELLE, N, GUTTMAN, M

“…To identify a haplotype influencing onset age for Parkinson's disease (PD) in the PARK3 region on chromosome 2p13. Single nucleotide polymorphisms (SNP)…”
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Epidemiologic study of 203 sibling pairs with Parkinson's disease: The GenePD study by MAHER, N. E, GOLBE, L. I, FELDMAN, R. G, GUTTMAN, M, LEW, M, SCHUMAN, S, SUCHOWERSKY, O, LAFONTAINE, A. L, LABELLE, N, VIEREGGE, P, PRAMSTALLER, P. P, KLEIN, C, LAZZARINI, A. M, HUBBLE, J, REIDER, C, GROWDON, J, WATTS, R, MONTGOMERY, E, BAKER, K, SINGER, C, STACY, M, MYERS, R. H, MARK, M. H, CURRIE, L. J, WOOTEN, G. F, SAINT-HILAIRE, M, WILK, J. B, VOLCJAK, J, MAHER, J. E

“…To examine patterns of familial aggregation and factors influencing onset age in a sample of siblings with PD. Sibling pairs (n = 203) with PD were collected…”
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Mitochondrial Dysfunction in Cybrid Lines Expressing Mitochondrial Genes from Patients with Progressive Supranuclear Palsy by Swerdlow, R. H., Golbe, L. I., Parks, J. K., Cassarino, D. S., Binder, D. R., Grawey, A. E., Litvan, I., Bennett, J. P., Wooten, G. F., Parker, W. D.

“…: Progressive supranuclear palsy (PSP) is a neurodegenerative movement disorder of unknown etiology. We hypothesized that mitochondrial DNA (mtDNA) aberration…”
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Absence of previously reported variants in the SCNA (G88C and G209A), NR4A2 (T291D and T245G) and the DJ-1 (T497C) genes in familial Parkinson's disease from the GenePD study by Karamohamed, Samer, Golbe, L.I., Mark, M.H., Lazzarini, A.M., Suchowersky, O., Labelle, N., Guttman, Mark, Currie, L.J., Wooten, G.F., Stacy, M., Saint-Hilaire, M., Feldman, R.G., Liu, J., Shoemaker, C.M., Wilk, J.B., DeStefano, A.L., Latourelle, J.C., Xu, G., Watts, R., Growdon, J., Lew, M., Waters, C., Vieregge, P., Pramstaller, P.P., Klein, C., Racette, B.A., Perlmutter, J.S., Parsian, A., Singer, Carlos, Montgomery, E., Baker, K., Gusella, J.F., Herbert, A., Myers, R.H.

“…Parkinson's disease (PD) is a neurodegenerative disorder in which relatives of the probands are affected approximately 4 times as frequently as relatives of…”
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Effect of chronic oral domperidone therapy on gastrointestinal symptoms and gastric emptying in patients with parkinson's disease by Soykan, Irfan, Sarosiek, Irene, Shifflett, Jeannie, Wooten, George F., McCallum, Richard W.

“…This study investigated whether domperidone could improve gastrointestinal symptoms in patients with Parkinson's disease who were receiving levodopa therapy. A…”
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Matrilineal inheritance of complex I dysfunction in a multigenerational Parkinson's disease family by Swerdlow, R H, Parks, J K, Davis, 2nd, J N, Cassarino, D S, Trimmer, P A, Currie, L J, Dougherty, J, Bridges, W S, Bennett, Jr, J P, Wooten, G F, Parker, W D

“…Recent data suggesting complex I dysfunction in Parkinson's disease (PD) arises from mitochondrial DNA (mtDNA) mutation does not conclusively answer whether…”
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Diagnosis and Initial Management of Parkinson's Disease by Nutt, John G, Wooten, G. Frederick

“…A 62-year-old man presents with an intermittent tremor in his left hand and some vague discomfort in the left arm. Physical examination shows a minimal rest…”
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Gender ratio differences between Parkinson's disease patients and their affected relatives by Swerdlow, R.H., Parker, W.D., Currie, L.J., Bennett, J.P., Harrison, M.B., Trugman, J.M., Wooten, G.F.

“…Mitochondrial dysfunction in Parkinson's disease (PD) is suspected to arise from either acquired or inherited mutation of mitochondrial DNA (mtDNA). If…”
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Genome-wide scan for Parkinson's disease: The genePD Study by DESTEFANO, A. L, GOLBE, L. I, LAFONTAINE, A. L, LABELLE, N, LEW, M. F, WATERS, C. H, GROWDON, J. H, SINGER, C, CURRIE, L. J, WOOTEN, G. F, VIEREGGE, P, PRAMSTALLER, P. P, MARK, M. H, KLEIN, C, HUBBLE, J. P, STACY, M, MONTGOMERY, E, MACDONALD, M. E, GUSELLA, J. F, MYERS, R. H, LAZZARINI, A. M, MAHER, N. E, SAINT-HILAIRE, M, FELDMAN, R. G, GUTTMAN, M, WATTS, R. L, SUCHOWERSKY, O

“…A genome-wide scan for idiopathic PD in a sample of 113 PD-affected sibling pairs is reported. Suggestive evidence for linkage was found for chromosomes 1 (214…”
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Clinical correlates of sleep benefit in Parkinson's disease by CURRIE, L. J, BENNETT, J. P, HARRISON, M. B, TRUGMAN, J. M, WOOTEN, G. F

“…The phenomenon of sleep benefit, a period of lessened disability or feeling "on" upon awakening from sleep in the morning, has received scant attention in the…”
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