Search Results - "Wooten, David"

synergy: a Python library for calculating, analyzing and visualizing drug combination synergy by Wooten, David J, Albert, Réka

“…Abstract Summary Combinations of multiple pharmacological agents can achieve a substantial benefit over treatment with single agents alone. Combinations that…”
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Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers by Wooten, David J, Groves, Sarah M, Tyson, Darren R, Liu, Qi, Lim, Jing S, Albert, Réka, Lopez, Carlos F, Sage, Julien, Quaranta, Vito

“…Adopting a systems approach, we devise a general workflow to define actionable subtypes in human cancers. Applied to small cell lung cancer (SCLC), the…”
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Charting the Fragmented Landscape of Drug Synergy by Meyer, Christian T., Wooten, David J., Lopez, Carlos F., Quaranta, Vito

“…Even as the clinical impact of drug combinations continues to accelerate, no consensus on how to quantify drug synergy has emerged. Rather, surveying the…”
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Compensatory knowledge signaling in consumer word-of-mouth by Packard, Grant, Wooten, David B.

“…This paper extends prior research on consumer knowledge beliefs and word-of-mouth transmission. Findings from four studies suggest that people compensate for…”
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Mathematical modeling of the Candida albicans yeast to hyphal transition reveals novel control strategies by Wooten, David J, Zañudo, Jorge Gómez Tejeda, Murrugarra, David, Perry, Austin M, Dongari-Bagtzoglou, Anna, Laubenbacher, Reinhard, Nobile, Clarissa J, Albert, Réka

“…Candida albicans, an opportunistic fungal pathogen, is a significant cause of human infections, particularly in immunocompromised individuals. Phenotypic…”
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When Boastful Word of Mouth Helps versus Hurts Social Perceptions and Persuasion by PACKARD, GRANT, GERSHOFF, ANDREW D., WOOTEN, DAVID B.

“…Although self-enhancement has recently been established as a central motive for sharing word-of-mouth information, little is known about the impact of…”
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The Presenter’s Paradox in customer service interactions by Kang, Christine, Wooten, David B.

“…This study examines the Presenter’s Paradox in the context of customer–server interactions. Our findings from four studies suggest that, in response to service…”
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MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery by Wooten, David J., Meyer, Christian T., Lubbock, Alexander L. R., Quaranta, Vito, Lopez, Carlos F.

“…Drug combination discovery depends on reliable synergy metrics but no consensus exists on the correct synergy criterion to characterize combined interactions…”
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Trophic Ecology of Seahorse Key, Florida: A Unique Bird-Snake Interaction Network Analysis by Wooten, David A

“…In 2015 the entire breeding colony of nesting waterbirds on Seahorse Key (Florida, U.S.A.) unexpectedly abandoned the island and have not returned. These birds…”
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Trophic Ecology of Seahorse Key, Florida: A Unique Bird-Snake Interaction Network Analysis by Wooten, David A.

“…In 2015 the entire breeding colony of nesting waterbirds on Seahorse Key (Florida, U.S.A.) unexpectedly abandoned the island and have not returned. These birds…”
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Mathematical models of cell phenotype regulation and reprogramming: Make cancer cells sensitive again by Wooten, David J., Quaranta, Vito

“…A cell's phenotype is the observable actualization of complex interactions between its genome, epigenome, and local environment. While traditional views in…”
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Marketing at Ross: 100 Years of Academic and Business Impact by Wooten, David B., Aribarg, Anocha

“…As our school approaches its centennial celebration, the entire Michigan-Ross community has been reflecting on its history of leadership and impact. This…”
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From Labeling Possessions to Possessing Labels: Ridicule and Socialization among Adolescents by Wooten, David B.

“…This research explores ridicule as a mechanism through which adolescents exchange information about consumption norms and values. The author finds that…”
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Novel Hybrid Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model That Can Explain Tumor Heterogeneity by Udyavar, Akshata R, Wooten, David J, Hoeksema, Megan, Bansal, Mukesh, Califano, Andrea, Estrada, Lourdes, Schnell, Santiago, Irish, Jonathan M, Massion, Pierre P, Quaranta, Vito

“…Small cell lung cancer (SCLC) is a devastating disease due to its propensity for early invasion and refractory relapse after initial treatment response…”
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Reconsidering gaps between perceived and real discrimination: commentary on the Galak and Kahn 2019 Academic Marketing Climate Survey by Wooten, David B., Ferguson, Nakeisha S.

“…Understanding and mitigating factors that adversely affect an institution’s diversity, equity, and inclusion initiatives have moved to the forefront of many…”
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Quantifying Drug Combination Synergy along Potency and Efficacy Axes by Meyer, Christian T, Wooten, David J, Paudel, B Bishal, Bauer, Joshua, Hardeman, Keisha N, Westover, David, Lovly, Christine M, Harris, Leonard A, Tyson, Darren R, Quaranta, Vito

“…Two goals motivate treating diseases with drug combinations: reduce off-target toxicity by minimizing doses (synergistic potency) and improve outcomes by…”
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The significance and meaning of racial identity in consumer research: A review and call for research by Wooten, David B., Rank‐Christman, Tracy

“…This article uses the Multidimensional Model of Racial Identity (MMRI) as a framework to broaden the current understanding of racial identity, structure our…”
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Selenium Induces Pancreatic Cancer Cell Death Alone and in Combination with Gemcitabine by Wooten, David J, Sinha, Indu, Sinha, Raghu

“…Survival rate for pancreatic cancer remains poor and newer treatments are urgently required. Selenium, an essential trace element, offers protection against…”
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Ventricular-Subventricular Zone Contact by Glioblastoma is Not Associated with Molecular Signatures in Bulk Tumor Data by Mistry, Akshitkumar M., Wooten, David J., Davis, L. Taylor, Mobley, Bret C., Quaranta, Vito, Ihrie, Rebecca A.

“…Whether patients with glioblastoma that contacts the ventricular-subventricular zone stem cell niche (VSVZ + GBM) have a distinct survival profile from VSVZ −…”
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Longitudinal monitoring of circulating tumor DNA to detect relapse early and predict outcome in early breast cancer by Garcia-Murillas, Isaac, Cutts, Rosalind J, Walsh-Crestani, Giselle, Phillips, Edward, Hrebien, Sarah, Dunne, Kathryn, Sidhu, Kally, Daber, Robert, Hubert, Benjamin, Graybill, Chiharu, DeFord, Peter M, Wooten, David J, Zhao, Jianhua, Ellsworth, Rachel E, Johnston, Stephen R D, Ring, Alistair, Russell, Simon, Evans, Abigail, Skene, Anthony, Wheatley, Duncan, Smith, Ian E, Korn, W Michael, Turner, Nicholas C

“…Detection of molecular residual disease (MRD) allows for the identification of breast cancer patients at high-risk of recurrence, with the potential that early…”
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