Correlation of Dietary Calcium, Phosphorus, and Magnesium Intakes to Bone Mineral Density in Caucasian Women Indentified by Specific Genotypes for Vitamin D Receptors and Collagen

Correlation of Dietary Calcium, Phosphorus, and Magnesium Intakes to Bone Mineral Density in Caucasian Women Indentified by Specific Genotypes for Vitamin D Receptors and Collagen

Major mineral nutrient intakes, bone mineral density and body composition analyses were performed on women in a follow-up study two years after participation in a study identifying subject's polymorphisms of vitamin D receptor and collagen genotypes. Non-smoking, Caucasian females (n=68) return...

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Bibliographic Details
Published in:Journal of the American Dietetic Association Vol. 98; no. 9; p. A59
Main Authors: Meacham, S.L., Wooten, C.S., Kiebzak, G.M., Brooks, G.T.
Format: Journal Article
Language:English
Published: Elsevier Inc 01-09-1998
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Summary:Major mineral nutrient intakes, bone mineral density and body composition analyses were performed on women in a follow-up study two years after participation in a study identifying subject's polymorphisms of vitamin D receptor and collagen genotypes. Non-smoking, Caucasian females (n=68) returned for follow-up bone densitometry by Lunar dual energy x-ray absorptiometry (DPX-L) (Lunar Radiation Corp., Madison, WI). Diet analyses were performed on 3 day food records using Food Processor for Windows (ESHA Research, Version 6.0, Salem, OR). Total bone mineral density (mean±MSE, 1.16±0.07 g/cm 2) was positively correlated to dietary calcium (p=0.02) and phosphorus (p=0.05). Body mass index [body weight (kg)/height (m 2)] (mean±MSE=23.46) was positively correlated to dietary calcium (p=0.04) and dietary phosphorus (p=0.01). Bone mineral content of lumbar spine (L2-L4), greater trocanter, Ward's area, and femoral neck were consistently dependent upon exercise (P<0.05). The correlation of dietary calcium, phosphorus, magnesium and exercise to total skeletal calcium did not attain significance (p=0.07, 0.09, 0.07, and 0.07, respectively). Data reported are part of a larger study including additional nutrient analyses, exercise, body composition, hormonal status and genotype classifications. Providing nutritional information to patients identified by genotypes specific to bone mineral density may assist dietitians with development of medical therapies for patients at risk for osteoporosis.
ISSN:0002-8223
1878-3570
DOI:10.1016/S0002-8223(98)00511-2