Search Results - "Woon-Kyu Lee"
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1
HDAC6 regulates cellular viral RNA sensing by deacetylation of RIG-I
Published in The EMBO journal (15-02-2016)“…RIG‐I is a key cytosolic sensor that detects RNA viruses through its C‐terminal region and activates the production of antiviral interferons (IFNs) and…”
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2
LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum
Published in Proceedings of the National Academy of Sciences - PNAS (07-08-2007)“…Purkinje cells are one of the major types of neurons that form the neural circuitry in the cerebellum essential for fine control of movement and posture…”
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3
Selective deletion of hepatocyte platelet-derived growth factor receptor α and development of liver fibrosis in mice
Published in Cell communication and signaling (03-12-2018)“…Platelet-derived growth factor receptor α (PDGFRα) expression is increased in activated hepatic stellate cells (HSCs) in cirrhotic liver, while normal…”
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4
Targeted Disruption of the Wnt Regulator Kremen Induces Limb Defects and High Bone Density
Published in Molecular and Cellular Biology (01-08-2008)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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5
Characterization of the porcine Nanog 5'-flanking region
Published in Animal bioscience (01-03-2018)“…Nanog, a homeodomain protein, has been investigated in humans and mice using embryonic stem cells (ESCs). Because of the limited availability of ESCs, few…”
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6
Transcription Factor KLF10 Constrains IL-17-Committed Vγ4 + γδ T Cells
Published in Frontiers in immunology (28-02-2018)“…γδ T cells, known to be an important source of innate IL-17 in mice, provide critical contributions to host immune responses. Development and function of γδ T…”
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7
Early changes in retinal structure and BMP2 expression in the retina and crystalline lens of streptozotocin-induced diabetic pigs
Published in Laboratory animal research (01-09-2017)“…This study aims to evaluate early changes in retinal structure and BMP2 expression in the retina and crystalline lens by comparing streptozotocin-induced…”
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8
Molecular Characterization and Expression Analysis of the Peroxisome Proliferator Activated Receptor Delta (PPARδ) Gene before and after Exercise in Horse
Published in Animal bioscience (01-05-2015)“…While athletic abilities such as speed, endurance and recovery are important in the horse, genes related to these abilities have not been extensively…”
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9
A Modified Protocol of Diethylnitrosamine Administration in Mice to Model Hepatocellular Carcinoma
Published in International journal of molecular sciences (30-07-2020)“…We aimed to create an animal model for hepatocellular carcinoma (HCC) with a short time, a high survival rate, as well as a high incidence of HCC in both males…”
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10
Characterization of the Nanog 5'-flanking Region in Bovine
Published in Animal bioscience (01-10-2016)“…Bovine embryonic stem cells have potential for use in research, such as transgenic cattle generation and the study of developmental gene regulation. The Nanog…”
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11
Phthalic anhydride-induced skin inflammation is augmented in KLF10-deficient mice
Published in Journal of dermatological science (01-09-2013)Get full text
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12
Loss of Krüppel-like factor-10 facilitates the development of chemical-induced liver cancer in mice
Published in Molecular medicine (Cambridge, Mass.) (09-11-2023)“…BACKGROUNDKrüppel-like factor 10 (KLF10) is involved in a positive feedback loop that regulates transforming growth factor β (TGFβ) signaling, and TGFβ plays…”
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13
Clusterin overexpression protects against western diet-induced obesity and NAFLD
Published in Scientific reports (15-10-2020)“…Obesity is a significant risk factor for various metabolic diseases and is closely related to non-alcoholic fatty liver disease (NAFLD) characterized by…”
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14
Gastroprotective effect of phytoncide extract from Pinus koraiensis pinecone in Helicobacter pylori infection
Published in Scientific reports (12-06-2020)“…For centuries, herbs have been used by traditional therapists around the world to treat gastrointestinal tract disorders, such as gastritis. We hypothesized…”
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15
Co-localization and interaction of human organic anion transporter 4 with caveolin-1 in primary cultured human placental trophoblasts
Published in Experimental & molecular medicine (31-10-2008)“…The human organic anion transporter 4 (hOAT4) has been identified as the fourth isoform of OAT family. hOAT4 contributes to move several negatively charged…”
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16
Hepatocyte-specific clusterin overexpression attenuates diet-induced nonalcoholic steatohepatitis
Published in Biochemical and biophysical research communications (08-01-2018)“…Clusterin is a multifunctional glycoprotein that plays important roles and is up-regulated in liver diseases such as hepatitis and hepatocellular carcinoma…”
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17
Synergistic production of interleukin-23 by dendritic cells derived from cord blood in response to costimulation with LPS and IL-12
Published in Journal of leukocyte biology (01-09-2009)“…IL‐23 secretion from stimulated DCs, dependent on ERK1/2 and p38 MAPK, caused an induction of memory interferon‐γ‐secreting T cells. This study was performed…”
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18
KLF10 is a modulatory factor of chondrocyte hypertrophy in developing skeleton
Published in Journal of orthopaedic research (01-09-2020)“…To define the functional role of Krüppel‐like factor (KLF) 10 as a modulator of chondrocyte hypertrophy in developing skeleton, the developmental features in…”
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19
Opposing roles of HDAC6 in liver regeneration and hepatocarcinogenesis
Published in Cancer science (01-07-2022)“…Histone deacetylase 6 (HDAC6), a deacetylase of p53, has emerged as a privileged inhibitory target for cancer therapy because of its deacetylating activity for…”
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Anti-Inflammatory Effect of Phytoncide in an Animal Model of Gastrointestinal Inflammation
Published in Molecules (Basel, Switzerland) (26-03-2021)“…Phytoncide is known to have antimicrobial and anti-inflammatory properties. This study was carried out to confirm the anti-inflammatory activity of two types…”
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