Search Results - "Woon Jung, Da"
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Cancer-Stimulated CAFs Enhance Monocyte Differentiation and Protumoral TAM Activation via IL6 and GM-CSF Secretion
Published in Clinical cancer research (01-11-2018)“…Abstract Purpose: M2-type TAMs are increasingly implicated as a crucial factor promoting metastasis. Numerous cell types dictate monocyte differentiation into…”
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2
Integrated drug response prediction models pinpoint repurposed drugs with effectiveness against rhabdomyosarcoma
Published in PloS one (26-01-2024)“…Targeted therapies for inhibiting the growth of cancer cells or inducing apoptosis are urgently needed for effective rhabdomyosarcoma (RMS) treatment. However,…”
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3
Cytoskeletal alteration modulates cancer cell invasion through RhoA-YAP signaling in stromal fibroblasts
Published in PloS one (28-03-2019)“…Cancer-associated fibroblasts(CAFs) participate in carcinogenesis through interaction with cancer cells. This study aimed to investigate the mechanism of…”
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4
Endocrine disrupting potential of selected azole and organophosphorus pesticide products through suppressing the dimerization of human androgen receptor in genomic pathway
Published in Ecotoxicology and environmental safety (01-12-2022)“…Several pesticides widely used in agriculture have been considered to be endocrine disrupting chemicals through their binding affinities to estrogen or…”
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Inhibiting 5‐lipoxygenase prevents skeletal muscle atrophy by targeting organogenesis signalling and insulin‐like growth factor‐1
Published in Journal of cachexia, sarcopenia and muscle (01-12-2022)“…Background Skeletal muscle atrophy can occur in response to numerous factors, such as ageing and certain medications, and produces a major socio‐economic…”
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Mechanistic insight into human androgen receptor-mediated endocrine disrupting potential of cyclic depsipeptide mycotoxin, beauvericin, and influencing environmental factors for its biosynthesis in Fusarium oxysporum KFCC 11363P on rice cereal
Published in Ecotoxicology and environmental safety (01-04-2024)“…In current study, Fusarium mycotoxin, beauvericin (BEA), has endocrine disrupting potential through suppressing the exogenous androgen receptor (AR)-mediated…”
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Tumor‐stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7
Published in International journal of cancer (15-07-2010)“…Recent studies have shown that stromal fibroblasts have a more profound influence on the initiation and progression of carcinoma than was previously…”
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Investigation of niclosamide as a repurposing agent for skeletal muscle atrophy
Published in PloS one (26-05-2021)“…Skeletal muscle atrophy is a feature of aging (termed sarcopenia) and various diseases, such as cancer and kidney failure. Effective drug treatment options for…”
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9
Analysis of Flow Characteristics of a Debris Filter in a Condenser Tube Cleaning System
Published in Energies (Basel) (01-06-2023)“…In a power plant that uses seawater as a coolant, a debris filter (DF) is required to remove foreign substances from the seawater, and differential pressure…”
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10
Age Is Just a Number: Progress and Obstacles in the Discovery of New Candidate Drugs for Sarcopenia
Published in Cells (Basel, Switzerland) (01-11-2023)“…Sarcopenia is a disease characterized by the progressive loss of skeletal muscle mass and function that occurs with aging. The progression of sarcopenia is…”
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Relationship between allergic rhinitis and nasal surgery success in patients with obstructive sleep apnea
Published in American journal of otolaryngology (01-11-2021)“…Nasal obstruction is common in patients with obstructive sleep apnea (OSA). Nonetheless, the effectiveness of isolated nasal surgery in treatment of OSA…”
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12
Biotransformed Metabolites of the Hop Prenylflavanone Isoxanthohumol
Published in Molecules (Basel, Switzerland) (22-01-2019)“…A metabolic conversion study on microbes is known as one of the most useful tools to predict the xenobiotic metabolism of organic compounds in mammalian…”
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13
Development of a Novel Detachable Magnetic Nerve Stimulator for Intraoperative Neuromonitoring
Published in World journal of surgery (2018)“…Background Recurrent laryngeal nerve (RLN) palsy is a serious complication of thyroid surgery. During intraoperative neuromonitoring (IONM) of the RLN in…”
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14
Areca nut exposure increases secretion of tumor‐promoting cytokines in gingival fibroblasts that trigger DNA damage in oral keratinocytes
Published in International journal of cancer (01-12-2015)“…Molecular crosstalk between cancer cells and fibroblasts has been an emerging hot issue in understanding carcinogenesis. As oral submucous fibrosis (OSF) is an…”
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Genome-Wide Transcriptomic Analysis of Non-Tumorigenic Tissues Reveals Aging-Related Prognostic Markers and Drug Targets in Renal Cell Carcinoma
Published in Cancers (18-06-2021)“…The relationship between expression of aging-related genes in normal tissues and cancer patient survival has not been assessed. We developed a genome-wide…”
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The relationship between foveal ischemia and spectral-domain optical coherence tomography findings in ischemic diabetic macular edema
Published in Investigative ophthalmology & visual science (07-02-2013)“…To investigate the relationship between enlargement of the foveal avascular zone (FAZ) and structural changes on spectral-domain optical coherence tomography…”
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17
ENOblock, a unique small molecule inhibitor of the non-glycolytic functions of enolase, alleviates the symptoms of type 2 diabetes
Published in Scientific reports (08-03-2017)“…Type 2 diabetes mellitus (T2DM) significantly impacts on human health and patient numbers are predicted to rise. Discovering novel drugs and targets for…”
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Reprogram or Reboot: Small Molecule Approaches for the Production of Induced Pluripotent Stem Cells and Direct Cell Reprogramming
Published in ACS chemical biology (17-01-2014)“…Stem cell transplantation is a potential therapy for regenerative medicine, which aims to restore tissues damaged by trauma, aging, and diseases. Since its…”
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Visualizing sweetness: increasingly diverse applications for fluorescent-tagged glucose bioprobes and their recent structural modifications
Published in Sensors (Basel, Switzerland) (01-04-2012)“…Glucose homeostasis is a fundamental aspect of life and its dysregulation is associated with important diseases, such as cancer and diabetes. Traditionally,…”
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Keeping your strength up: induced pluripotent stem cell-based approaches for the treatment and investigation of skeletal muscle disorders
Published in All life (Online) (31-12-2023)“…Skeletal muscle comprises the major organ system in our bodies and is the effector tissue for fundamental processes, such as movement, breathing and glucose…”
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