Search Results - "Woolsey, Sarah"

CYP3A Activity and Expression in Nonalcoholic Fatty Liver Disease by Woolsey, Sarah J, Mansell, Sara E, Kim, Richard B, Tirona, Rommel G, Beaton, Melanie D

“…Nonalcoholic fatty liver disease (NAFLD) is the leading cause of liver disease in the Western world, given its association with obesity, type 2 diabetes, and…”
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A Fibroblast Growth Factor 21-Pregnane X Receptor Pathway Downregulates Hepatic CYP3A4 in Nonalcoholic Fatty Liver Disease by Woolsey, Sarah J, Beaton, Melanie D, Mansell, Sara E, Leon-Ponte, Matilde, Yu, Janice, Pin, Christopher L, Adams, Paul C, Kim, Richard B, Tirona, Rommel G

“…Nonalcoholic fatty liver disease (NAFLD) alters drug response. We previously reported that NAFLD is associated with reduced in vivo CYP3A drug-metabolism…”
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Clarifying the importance of CYP2C19 and PON1 in the mechanism of clopidogrel bioactivation and in vivo antiplatelet response by Gong, Inna Y, Crown, Natalie, Suen, Colin M, Schwarz, Ute I, Dresser, George K, Knauer, Michael J, Sugiyama, Daisuke, DeGorter, Marianne K, Woolsey, Sarah, Tirona, Rommel G, Kim, Richard B

“…It is thought that clopidogrel bioactivation and antiplatelet response are related to cytochrome P450 2C19 (CYP2C19). However, a recent study challenged this…”
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Relationships between Endogenous Plasma Biomarkers of Constitutive Cytochrome P450 3A Activity and Single‐Time‐Point Oral Midazolam Microdose Phenotype in Healthy Subjects by Woolsey, Sarah J., Beaton, Melanie D., Choi, Yun‐Hee, Dresser, George K., Gryn, Steven E., Kim, Richard B., Tirona, Rommel G.

“…Due to high basal interindividual variation in cytochrome P450 3A (CYP3A) activity and susceptibility to drug interactions, there has been interest in the…”
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Pharmacist-provided diabetes management and education via a telemonitoring program by Shane-McWhorter, Laura, PharmD, BCPS, BC-ADM, CDE, FASCP, FAADE, McAdam-Marx, Carrie, PhD, Lenert, Leslie, MD, Petersen, Marta, MD, Woolsey, Sarah, MD, FAAFP, Coursey, Jeffrey M., PA-C, Whittaker, Thomas C., MD, Hyer, Christian, PA-C, LaMarche, Deb, BS, Carroll, Patricia, MS, Chuy, Libbey, MS

“…Abstract Objective To assess clinical outcomes (glycosylated hemoglobin [A1C], blood pressure, and lipids) and other measurements (disease state knowledge,…”
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Removal of sample background buffering ions and myoglobin enrichment via a pH junction created by discontinuous buffers in capillary electrophoresis by Booker, Christina J., Sun, Samuel, Woolsey, Sarah, Mejia, Jose S., Yeung, Ken K.-C.

“…Traditional CE sample stacking is ineffective for samples containing a high concentration of salt and/or buffer. We recently reported the use of a…”
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Diagnosing Hypertension in Primary Care Clinics According to Current Guidelines by Woolsey, Sarah, Brown, Brittany, Ralls, Brenda, Friedrichs, Michael, Stults, Barry

“…This descriptive study examines hypertension diagnostic practices in Utah primary care clinics relative to the 2015 US Preventive Services Task Force (USPSTF)…”
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Use of unattended automated office blood pressure in Utah primary care clinics by Stuligross, John, Hoj, Taylor H., Brown, Brittany, Woolsey, Sarah, Stults, Barry

“…Unattended automated office blood pressure (BP) measurement (u-AOBP) improves office BP measurement accuracy and reduces white-coat BP elevation. u-AOBP is…”
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Use of unattended automated office blood pressure in Utah primary care clinics by Stuligross, John, Hoj, Taylor H., Brown, Brittany, Woolsey, Sarah, Stults, Barry

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Trimethylamine-N-oxide: A Novel Biomarker for the Identification of Inflammatory Bowel Disease by Wilson, Aze, Teft, Wendy A., Morse, Bridget L., Choi, Yun-Hee, Woolsey, Sarah, DeGorter, Marianne K., Hegele, Robert A., Tirona, Rommel G., Kim, Richard B.

“…Background The gastrointestinal (GI) microbiome is recognized for potential clinical relevance in inflammatory bowel disease (IBD). Data suggest that there is…”
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Going mobile with diabetes support: a randomized study of a text message-based personalized behavioral intervention for type 2 diabetes self-care by Capozza, Korey, Woolsey, Sarah, Georgsson, Mattias, Black, Jeff, Bello, Nelly, Lence, Clare, Oostema, Steve, North, Christie

“…Objective. Patients with type 2 diabetes often fail to achieve self-management goals. This study tested the impact on glycemic control of a two-way text…”
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Use of transgenic mouse models to understand the oral disposition and drug-drug interaction potential of cobimetinib, a MEK inhibitor by Choo, Edna F, Woolsey, Sarah, DeMent, Kevin, Ly, Justin, Messick, Kirsten, Qin, Ann, Takahashi, Ryan

“…Data from the clinical absolute bioavailability (F) study with cobimetinib suggested that F was lower than predicted based on its low hepatic extraction and…”
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ACR Appropriateness Criteria® Screening for Abdominal Aortic Aneurysm by Lee, Yoo Jin, Aghayev, Ayaz, Azene, Ezana M., Bhatti, Salman, Ewell, Joshua C., Hedgire, Sandeep S., Kendi, A. Tuba, Kim, Esther S.H., Kirsch, David S., Nagpal, Prashant, Pillai, Anil K., Ripley, Beth, Tannenbaum, Andrew, Thiessen, Molly E.W., Thomas, Richard, Woolsey, Sarah, Steigner, Michael L.

“…Abdominal aortic aneurysm (AAA) is a significant vascular disease found in 4% to 8% of the screening population. If ruptured, its mortality rate is between 75%…”
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ACR Appropriateness Criteria® Dizziness and Ataxia: 2023 Update by Wang, Lily L., Thompson, Trevor A., Shih, Robert Y., Ajam, Amna A., Bulsara, Ketan, Burns, Judah, Davis, Melissa A., Ivanidze, Jana, Kalnins, Aleks, Kuo, Phillip H., Ledbetter, Luke N., Pannell, Jeffrey S., Pollock, Jeffrey M., Shakkottai, Vikram G., Shih, Richard D., Soares, Bruno P., Soderlund, Karl A., Utukuri, Pallavi S., Woolsey, Sarah, Policeni, Bruno

“…Diagnostic evaluation of a patient with dizziness or vertigo is complicated by a lack of standardized nomenclature, significant overlap in symptom…”
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Trimethylamine-N-oxide: A Novel Biomarker for the Identification of Inflammatory Bowel Disease: 1818 by Wilson, Aze, Teft, Wendy, Tirona, Rommel, Woolsey, Sarah, Morse, Bridget, DeGorter, Marianne, Hegele, Robert, Choi, Yun-Hee, Kim, Richard

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The Utah Remote Monitoring Project: improving health care one patient at a time by Shane-McWhorter, Laura, Lenert, Leslie, Petersen, Marta, Woolsey, Sarah, McAdam-Marx, Carrie, Coursey, Jeffrey M, Whittaker, Thomas C, Hyer, Christian, LaMarche, Deb, Carroll, Patricia, Chuy, Libbey

“…The expanding role of technology to augment diabetes care and management highlights the need for clinicians to learn about these new tools. As these tools…”
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Regulation of Cytochrome P450 3A4 in Non‐Alcoholic Fatty Liver Disease by Fibroblast Growth Factor 21 by Woolsey, Sarah Joy, Gong, Inna, Kim, Richard, Levstik, Mark, Beaton, Melanie, Tirona, Rommel

“…Abstract only Non‐alcoholic fatty liver disease (NAFLD) is the most common cause of liver disease affecting approximately one third of adults. For a majority…”
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Mo1004 Among Nonalcoholic Fatty Liver Disease Patients Treated With Phlebotomy Does PNPLA3 Genotype Influence Changes in Gene Expression, Adipokines and Liver Histology? by Beaton, Melanie D, Summers, Kelly, Woolsey, Sarah, Choi, Yun-Hee, Tirona, Rommel G

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Relationships between Endogenous Plasma Biomarkers of Constitutive Cytochrome P 450 3 A Activity and Single‐Time‐Point Oral Midazolam Microdose Phenotype in Healthy Subjects by Woolsey, Sarah J., Beaton, Melanie D., Choi, Yun‐Hee, Dresser, George K., Gryn, Steven E., Kim, Richard B., Tirona, Rommel G.

“…Abstract Due to high basal interindividual variation in cytochrome P 450 3 A ( CYP 3 A ) activity and susceptibility to drug interactions, there has been…”
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Erratum to: Trimethylamine-N-oxide: A Novel Biomarker for the Identification of Inflammatory Bowel Disease by Wilson, Aze, Teft, Wendy A., Morse, Bridget L., Choi, Yun-Hee, Woolsey, Sarah, DeGorter, Marianne K., Hegele, Robert A., Tirona, Rommel G., Kim, Richard B.

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