Search Results - "Woollard, Peter M"

The application of next-generation sequencing technologies to drug discovery and development by Woollard, Peter M., Mehta, Nalini A.L., Vamathevan, Jessica J., Van Horn, Stephanie, Bonde, Bhushan K., Dow, David J.

“…Next-generation sequencing (NGS) technologies represent a paradigm shift in sequencing capability. The technology has already been extensively applied to…”
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Mining integrated semantic networks for drug repositioning opportunities by Mullen, Joseph, Cockell, Simon J, Tipney, Hannah, Woollard, Peter M, Wipat, Anil

“…Current research and development approaches to drug discovery have become less fruitful and more costly. One alternative paradigm is that of drug…”
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Minipig and beagle animal model genomes aid species selection in pharmaceutical discovery and development by Vamathevan, Jessica J., Hall, Matthew D., Hasan, Samiul, Woollard, Peter M., Xu, Meng, Yang, Yulan, Li, Xin, Wang, Xiaoli, Kenny, Steve, Brown, James R., Huxley-Jones, Julie, Lyon, Jon, Haselden, John, Min, Jiumeng, Sanseau, Philippe

“…Improving drug attrition remains a challenge in pharmaceutical discovery and development. A major cause of early attrition is the demonstration of safety…”
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Deep Resequencing Unveils Genetic Architecture of ADIPOQ and Identifies a Novel Low-Frequency Variant Strongly Associated With Adiponectin Variation by WARREN, Liling L, LI LI, HALL, Matt D, TOPP, Simon D, XIN YUAN, CARDON, Lon R, CHISSOE, Stephanie L, MOOSER, Vincent, MORRIS, Andrew D, PALMER, Colin N. A, PERRY, John R, FRAYLING, Timothy M, NELSON, Matthew R, WHITTAKER, John C, WATERWORTH, Dawn M, EHM, Margaret G, JUDONG SHEN, FRASER, Dana J, APONTE, Jennifer L, NANGLE, Keith L, SLATER, Andrew J, WOOLLARD, Peter M

“…Increased adiponectin levels have been shown to be associated with a lower risk of type 2 diabetes. To understand the relations between genetic variation at…”
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Asking complex questions of the genome without programming by Woollard, Peter M

“…Increasingly, vast amounts of genomics and genetic data are available. Although much of the data is largely accessible to relatively simple web queries, in…”
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