Search Results - "Woolfenden, Amber"

Identification of Bronchioalveolar Stem Cells in Normal Lung and Lung Cancer by Kim, Carla F. Bender, Jackson, Erica L., Woolfenden, Amber E., Lawrence, Sharon, Babar, Imran, Vogel, Sinae, Crowley, Denise, Bronson, Roderick T., Jacks, Tyler

“…Injury models have suggested that the lung contains anatomically and functionally distinct epithelial stem cell populations. We have isolated such a regional…”
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Primary Tumor Genotype Is an Important Determinant in Identification of Lung Cancer Propagating Cells by Curtis, Stephen J., Sinkevicius, Kerstin W., Li, Danan, Lau, Allison N., Roach, Rebecca R., Zamponi, Raffaella, Woolfenden, Amber E., Kirsch, David G., Wong, Kwok-Kin, Kim, Carla F.

“…Successful cancer therapy requires the elimination or incapacitation of all tumor cells capable of regenerating a tumor. Therapeutic advances therefore…”
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Pharmacologic Uncoupling of Angiogenesis and Inflammation during Initiation of Pathological Corneal Neovascularization by Sivak, Jeremy M., Ostriker, Allison C., Woolfenden, Amber, Demirs, John, Cepeda, Rosemarie, Long, Debby, Anderson, Karen, Jaffee, Bruce

“…Pathological neovascularization occurs when a balance of pro- and anti-angiogenic factors is disrupted, accompanied by an amplifying inflammatory cascade…”
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Lack of involvement of CEP adducts in TLR activation and in angiogenesis by Gounarides, John, Cobb, Jennifer S, Zhou, Jing, Cook, Frank, Yang, Xuemei, Yin, Hong, Meredith, Erik, Rao, Chang, Huang, Qian, Xu, YongYao, Anderson, Karen, De Erkenez, Andrea, Liao, Sha-Mei, Crowley, Maura, Buchanan, Natasha, Poor, Stephen, Qiu, Yubin, Fassbender, Elizabeth, Shen, Siyuan, Woolfenden, Amber, Jensen, Amy, Cepeda, Rosemarie, Etemad-Gilbertson, Bijan, Giza, Shelby, Mogi, Muneto, Jaffee, Bruce, Azarian, Sassan

“…Proteins that are post-translationally adducted with 2-(ω-carboxyethyl)pyrrole (CEP) have been proposed to play a pathogenic role in age-related macular…”
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Reliability of the mouse model of choroidal neovascularization induced by laser photocoagulation by Poor, Stephen H, Qiu, Yubin, Fassbender, Elizabeth S, Shen, Siyuan, Woolfenden, Amber, Delpero, Andrea, Kim, Yong, Buchanan, Natasha, Gebuhr, Thomas C, Hanks, Shawn M, Meredith, Erik L, Jaffee, Bruce D, Dryja, Thaddeus P

“…We attempted to reproduce published studies that evaluated whether the following factors influence choroidal neovascularization (CNV) induced by laser…”
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The Discovery of N‑(1-Methyl-5-(trifluoromethyl)‑1H‑pyrazol-3-yl)-5-((6- ((methylamino)methyl)pyrimidin-4-yl)oxy)‑1H‑indole-1-carboxamide (Acrizanib), a VEGFR‑2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration by Adams, Christopher M, Anderson, Karen, Artman, Gerald, Bizec, Jean-Claude, Cepeda, Rosemarie, Elliott, Jason, Fassbender, Elizabeth, Ghosh, Malay, Hanks, Shawn, Hardegger, Leo A, Hosagrahara, Vinayak P, Jaffee, Bruce, Jendza, Keith, Ji, Nan, Johnson, Leland, Lee, Wendy, Liu, Donglei, Liu, Fang, Long, Debby, Ma, Fupeng, Mainolfi, Nello, Meredith, Erik L, Miranda, Karl, Peng, Yao, Poor, Stephen, Powers, James, Qiu, Yubin, Rao, Chang, Shen, Siyuan, Sivak, Jeremy M, Solovay, Catherine, Tarsa, Peter, Woolfenden, Amber, Zhang, Chun, Zhang, Yiqin

“…A noninvasive topical ocular therapy for the treatment of neovascular or “wet” age-related macular degeneration would provide a patient administered…”
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Discovery of Oral VEGFR‑2 Inhibitors with Prolonged Ocular Retention That Are Efficacious in Models of Wet Age-Related Macular Degeneration by Meredith, Erik L, Mainolfi, Nello, Poor, Stephen, Qiu, Yubin, Miranda, Karl, Powers, James, Liu, Donglei, Ma, Fupeng, Solovay, Catherine, Rao, Chang, Johnson, Leland, Ji, Nan, Artman, Gerald, Hardegger, Leo, Hanks, Shawn, Shen, Siyuan, Woolfenden, Amber, Fassbender, Elizabeth, Sivak, Jeremy M, Zhang, Yiqin, Long, Debby, Cepeda, Rosemarie, Liu, Fang, Hosagrahara, Vinayak P, Lee, Wendy, Tarsa, Peter, Anderson, Karen, Elliott, Jason, Jaffee, Bruce

“…The benefit of intravitreal anti-VEGF therapy in treating wet age-related macular degeneration (AMD) is well established. Identification of VEGFR-2 inhibitors…”
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The Discovery of N -(1-Methyl-5-(trifluoromethyl)-1 H -pyrazol-3-yl)-5-((6- ((methylamino)methyl)pyrimidin-4-yl)oxy)-1 H -indole-1-carboxamide (Acrizanib), a VEGFR-2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration by Adams, Christopher M., Anderson, Karen, Artman, Gerald, Bizec, Jean-Claude, Cepeda, Rosemarie, Elliott, Jason, Fassbender, Elizabeth, Ghosh, Malay, Hanks, Shawn, Hardegger, Leo A., Hosagrahara, Vinayak P., Jaffee, Bruce, Jendza, Keith, Ji, Nan, Johnson, Leland, Lee, Wendy, Liu, Donglei, Liu, Fang, Long, Debby, Ma, Fupeng, Mainolfi, Nello, Meredith, Erik L., Miranda, Karl, Peng, Yao, Poor, Stephen, Powers, James, Qiu, Yubin, Rao, Chang, Shen, Siyuan, Sivak, Jeremy M., Solovay, Catherine, Tarsa, Peter, Woolfenden, Amber, Zhang, Chun, Zhang, Yiqin

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