Search Results - "Woodworth, B."

Building a lineage from single cells: genetic techniques for cell lineage tracking by Woodworth, Mollie B., Girskis, Kelly M., Walsh, Christopher A.

“…Key Points Methods for tracing lineage can be divided into two groups. Prospective methods trace lineage forwards from the application of an experimentally…”
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Molecular logic of neocortical projection neuron specification, development and diversity by Greig, Luciano Custo, Woodworth, Mollie B., Galazo, Maria J., Padmanabhan, Hari, Macklis, Jeffrey D.

“…Key Points The sophisticated circuitry of the neocortex is assembled from a diverse repertoire of neuronal subtypes generated during development under precise…”
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Somatic mutation in single human neurons tracks developmental and transcriptional history by Lodato, Michael A., Woodworth, Mollie B., Lee, Semin, Evrony, Gilad D., Mehta, Bhaven K., Karger, Amir, Lee, Soohyun, Chittenden, Thomas W., D'Gama, Alissa M., Cai, Xuyu, Luquette, Lovelace J., Lee, Eunjung, Park, Peter J., Walsh, Christopher A.

“…Neurons live for decades in a postmitotic state, their genomes susceptible to DNA damage. Here we survey the landscape of somatic single-nucleotide variants…”
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Somatic Mutations Activating the mTOR Pathway in Dorsal Telencephalic Progenitors Cause a Continuum of Cortical Dysplasias by D’Gama, Alissa M., Woodworth, Mollie B., Hossain, Amer A., Bizzotto, Sara, Hatem, Nicole E., LaCoursiere, Christopher M., Najm, Imad, Ying, Zhong, Yang, Edward, Barkovich, A. James, Kwiatkowski, David J., Vinters, Harry V., Madsen, Joseph R., Mathern, Gary W., Blümcke, Ingmar, Poduri, Annapurna, Walsh, Christopher A.

“…Focal cortical dysplasia (FCD) and hemimegalencephaly (HME) are epileptogenic neurodevelopmental malformations caused by mutations in mTOR pathway genes. Deep…”
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Ctip1 Controls Acquisition of Sensory Area Identity and Establishment of Sensory Input Fields in the Developing Neocortex by Greig, Luciano C., Woodworth, Mollie B., Greppi, Chloé, Macklis, Jeffrey D.

“…While transcriptional controls over the size and relative position of cortical areas have been identified, less is known about regulators that direct…”
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BEAM: A combinatorial recombinase toolbox for binary gene expression and mosaic genetic analysis by Greig, Luciano C., Woodworth, Mollie B., Poulopoulos, Alexandros, Lim, Stephanie, Macklis, Jeffrey D.

“…We describe a binary expression aleatory mosaic (BEAM) system, which relies on DNA delivery by transfection or viral transduction along with nested recombinase…”
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Katanin p80 Regulates Human Cortical Development by Limiting Centriole and Cilia Number by Hu, Wen F., Pomp, Oz, Ben-Omran, Tawfeg, Kodani, Andrew, Henke, Katrin, Mochida, Ganeshwaran H., Yu, Timothy W., Woodworth, Mollie B., Bonnard, Carine, Raj, Grace Selva, Tan, Thong Teck, Hamamy, Hanan, Masri, Amira, Shboul, Mohammad, Al Saffar, Muna, Partlow, Jennifer N., Al-Dosari, Mohammed, Alazami, Anas, Alowain, Mohammed, Alkuraya, Fowzan S., Reiter, Jeremy F., Harris, Matthew P., Reversade, Bruno, Walsh, Christopher A.

“…Katanin is a microtubule-severing complex whose catalytic activities are well characterized, but whose in vivo functions are incompletely understood. Human…”
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Ctip1 Regulates the Balance between Specification of Distinct Projection Neuron Subtypes in Deep Cortical Layers by Woodworth, Mollie B., Greig, Luciano C., Liu, Kevin X., Ippolito, Gregory C., Tucker, Haley O., Macklis, Jeffrey D.

“…The molecular linkage between neocortical projection neuron subtype and area development, which enables the establishment of functional areas by projection…”
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Mechanics of particulate composites with glassy polymer binders in compression by Jordan, J. L., Spowart, J. E., Kendall, M. J., Woodworth, B., Siviour, C. R.

“…Whether used as structural components in design or matrix materials for composites, the mechanical properties of polymers are increasingly important. The…”
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Coblation for epistaxis management in patients with hereditary haemorrhagic telangiectasia: a multicentre case series by Joshi, H, Woodworth, B A, Carney, A S

“…To propose radiofrequency coblation as a potential treatment modality for mild to moderate epistaxis in patients with hereditary haemorrhagic telangiectasia…”
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Increased compression in HDC-based ablator implosions using modified drive profile by Tommasini, R., Casey, D. T., Clark, D., Do, A., Baker, K. L., Landen, O. L., Smalyuk, V. A., Weber, C., Bachmann, B., Hartouni, E., Kerr, S., Krauland, C., Marley, E. V., Millot, M., Milovich, J., Nora, R. C., Pak, A. E., Schlossberg, D., Woodworth, B., Briggs, T. M., Holunga, D. M., Nikroo, A., Stadermann, M.

“…Compression is an essential component of achieving high gain in inertial confinement fusion. However, increasing compression with crystalline ablator-based…”
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Endoscopic resection of intracranial dermoid cysts by Schuster, D, Riley, K O, Cure, J K, Woodworth, B A

“…Nasal dermoid cysts are congenital lesions which are often diagnosed in infancy or childhood. However, a small number present in adulthood, and some extend…”
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OP 1.4 – 00053 Definitive evidence of a persistent HIV reservoir in human brain myeloid cells despite ART by Y. Tang, G. Jiang, M. Porrachia, C. Ignacio, L.M. Wong, D. Zhong, J. Du, B. Cotsakis, S. Maske, E. de la Parra Polina, T.L. Simermeyer, D. Li, B. Woodworth, J. Kirchherr, B. Allard, M. Clohosey, G.D. Whitehill, J.J. Eron, N.M. Archin, S.B. Joseph, K. Bar, A. Chaillon, S. Gianella, D.M. Margolis, G. Jiang

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ΔF508 CFTR processing correction and activity in polarized airway and non-airway cell monolayers by Rowe, S.M, Pyle, L.C, Jurkevante, A, Varga, K, Collawn, J, Sloane, P.A, Woodworth, B, Mazur, M, Fulton, J, Fan, L, Li, Y, Fortenberry, J, Sorscher, E.J, Clancy, J.P

“…Abstract We examined the activity of ΔF508 cystic fibrosis transmembrane conductance regulator (CFTR) stably expressed in polarized cystic fibrosis bronchial…”
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Aging and neurodegeneration are associated with increased mutations in single human neurons by Lodato, Michael A, Rodin, Rachel E, Bohrson, Craig L, Coulter, Michael E, Barton, Alison R, Kwon, Minseok, Sherman, Maxwell A, Vitzthum, Carl M, Luquette, Lovelace J, Yandava, Chandri N, Yang, Pengwei, Chittenden, Thomas W, Hatem, Nicole E, Ryu, Steven C, Woodworth, Mollie B, Park, Peter J, Walsh, Christopher A

“…It has long been hypothesized that aging and neurodegeneration are associated with somatic mutation in neurons; however, methodological hurdles have prevented…”
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Endoscopic repair of frontal sinus cerebrospinal fluid leaks by Woodworth, B A, Schlosser, R J, Palmer, J N

“…To describe endoscopic management of frontal sinus cerebrospinal fluid (CSF) leaks. Retrospective. We reviewed all frontal sinus CSF leaks treated using an…”
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Intrinsic and Induced Neuronal Regeneration in the Mammalian Retina by Woodworth, Mollie B, Greig, Luciano C, Goldberg, Jeffrey L

“…Retinal neurons are vulnerable to disease and injury, which can result in neuronal death and degeneration leading to irreversible vision loss. The human retina…”
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Controlled Radical Polymerization in the Presence of Oxygen by Matyjaszewski, Krzysztof, Coca, Simion, Gaynor, Scott G, Wei, Mingli, Woodworth, Brian E

“…Living polymerizations occur without termination or transfer reactions and have the advantage of being able to form well-defined polymers with predictable…”
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A molecular switch for neuroprotective astrocyte reactivity by Cameron, Evan G., Nahmou, Michael, Toth, Anna B., Heo, Lyong, Tanasa, Bogdan, Dalal, Roopa, Yan, Wenjun, Nallagatla, Pratima, Xia, Xin, Hay, Sarah, Knasel, Cara, Stiles, Travis L., Douglas, Christopher, Atkins, Melissa, Sun, Catalina, Ashouri, Masoumeh, Bian, Minjuan, Chang, Kun-Che, Russano, Kristina, Shah, Sahil, Woodworth, Mollie B., Galvao, Joana, Nair, Ramesh V., Kapiloff, Michael S., Goldberg, Jeffrey L.

“…The intrinsic mechanisms that regulate neurotoxic versus neuroprotective astrocyte phenotypes and their effects on central nervous system degeneration and…”
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Frontal recess cells: a rare cause of frontal sinus pneumocoele by Dixon, J F, Woodworth, B A

“…A pneumocoele is a pathologically expanding, air-containing paranasal sinus. Pneumocoeles are uncommon entities, with very few cases reported in the…”
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