Search Results - "Woodward, Ruth A."

Structure-based design of a single-chain triple-disulfide-stabilized fusion-glycoprotein trimer that elicits high-titer neutralizing responses against human metapneumovirus by Ou, Li, Chen, Steven J, Teng, I-Ting, Yang, Lijuan, Zhang, Baoshan, Zhou, Tongqing, Biju, Andrea, Cheng, Cheng, Kong, Wing-Pui, Morano, Nicholas C, Stancofski, Erik-Stephane D, Todd, John-Paul, Tsybovsky, Yaroslav, Wang, Shuishu, Zheng, Cheng-Yan, Mascola, John R, Shapiro, Lawrence, Woodward, Ruth A, Buchholz, Ursula J, Kwong, Peter D

“…The Pneumoviridae family of viruses includes human metapneumovirus (HMPV) and respiratory syncytial virus (RSV). The closely related Paramyxoviridae family…”
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Anti-viral efficacy of a next-generation CD4-binding site bNAb in SHIV-infected animals in the absence of anti-drug antibody responses by Lovelace, Sarah E., Helmold Hait, Sabrina, Yang, Eun Sung, Fox, Madison L., Liu, Cuiping, Choe, Misook, Chen, Xuejun, McCarthy, Elizabeth, Todd, John-Paul, Woodward, Ruth A., Koup, Richard A., Mascola, John R., Pegu, Amarendra

“…Broadly neutralizing antibodies (bNAbs) against HIV-1 are promising immunotherapeutic agents for treatment of HIV-1 infection. bNAbs can be administered to…”
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Cholesterol reduction by immunization with a PCSK9 mimic by Zhang, Baoshan, Chuang, Gwo-Yu, Biju, Andrea, Biner, Daniel, Cheng, Jiaxuan, Wang, Yiran, Bao, Saran, Chao, Cara W., Lei, Haotian, Liu, Tracy, Nazzari, Alexandra F., Yang, Yongping, Zhou, Tongqing, Chen, Steven J., Chen, Xuejun, Kong, Wing-Pui, Ou, Li, Parchment, Danealle K., Sarfo, Edward K., SiMa, HaoMin, Todd, John-Paul, Wang, Shuishu, Woodward, Ruth A., Cheng, Cheng, Rawi, Reda, Mascola, John R., Kwong, Peter D.

“…Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a plasma protein that controls cholesterol homeostasis. Here, we design a human PCSK9 mimic, named…”
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Reproductive consequences of a matrilineal overthrow in rhesus monkeys by Dettmer, Amanda M., Woodward, Ruth A., Suomi, Stephen J.

“…Matrilineal overthrows in macaque societies are rare but devastating events, often resulting in severe morbidity, mortality, and loss of individual and group…”
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Mitochondrial compromise in 3-year old patas monkeys exposed in utero to human-equivalent antiretroviral therapies by Liu, Yongmin, Shim Park, Eunwoo, Gibbons, Alexander T., Shide, Eric D., Divi, Rao L., Woodward, Ruth A., Poirier, Miriam C.

“…Antiretroviral (ARV) drug therapy, given during pregnancy for prevention of mother‐to‐child transmission of human immunodeficiency virus 1 (HIV‐1), induces…”
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Perinatal Exposure of Patas Monkeys to Antiretroviral Nucleoside Reverse-Transcriptase Inhibitors Induces Genotoxicity Persistent for up to 3 Years of Age by Olivero, Ofelia A., Torres, Lorangelly Rivera, Gorjifard, Sayeh, Momot, Dariya, Marrogi, Eryney, Divi, Rao L., Liu, Yongmin, Woodward, Ruth A., Sowers, Marsha J., Poirier, Miriam C.

“…Background. Erythrocebus patas (patas) monkeys were used to model antiretroviral (ARV) drug in human immunodeficiency virus type 1—infected pregnant women…”
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Facial asymmetry is negatively related to condition in female macaque monkeys by Little, Anthony C., Paukner, Annika, Woodward, Ruth A., Suomi, Stephen J.

“…The face is an important visual trait in social communication across many species. In evolutionary terms, there are large and obvious selective advantages in…”
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Differential relationships between chronic hormone profiles in pregnancy and maternal investment in rhesus monkey mothers with hair loss in the neonatal period by Dettmer, Amanda M., Rosenberg, Kendra, Menard, Mark T., El‐Mallah, Saif N., Woodward, Ruth A., Suomi, Stephen J., Meyer, Jerrold S.

“…Hair loss is commonly used as an indicator of well being in primate facilities, yet it has been shown to also occur in otherwise healthy pregnant and…”
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The Influence of Age on Serum Concentrations of Cardiac Troponin I: Results in Rats, Monkeys, and Commercial Sera by Herman, Eugene H., Knapton, Alan, Liu, Yongmin, Lipshultz, Steven E., Estis, Joel, Todd, John, Woodward, Ruth A., Cochran, Thomas, Zhang, Jun, Poirier, Miriam C.

“…Cardiac troponins serve as serum biomarkers of myocardial injury. The current study examined the influence of age on serum concentrations of cardiac troponin I…”
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Tamoxifen–DNA adduct formation in monkey and human reproductive organs by Hernandez-Ramon, Elena E., Sandoval, Nicole A., John, Kaarthik, Cline, J.Mark, Wood, Charles E., Woodward, Ruth A., Poirier, Miriam C.

“…The estrogen analog tamoxifen (TAM), used for adjuvant therapy of breast cancer, induces endometrial and uterine tumors in breast cancer patients…”
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Genetic diversity of Klebsiella pneumoniae isolates during an outbreak in a non-human primate research colony by Gozalo, Alfonso S., Elkins, William R., Lambert, Lynn E., Stock, Frida, Thomas III, Marvin L., Woodward, Ruth A.

“…Background Klebsiella pneumoniae can be a serious pathogen in non‐human primates, particularly Neotropical monkeys. Methods During a K. pneumoniae outbreak in…”
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The effect of gonadectomy on prepulse inhibition and fear-potentiated startle in adolescent rhesus macaques by Morris, Richard W, Fung, Samantha J, Rothmond, Debora A, Richards, Brent, Ward, Sarah, Noble, Pamela L, Woodward, Ruth A, Weickert, Cynthia Shannon, Winslow, James T

“…Summary Sex steroids, such as testosterone, can regulate brain development, cognition and modify psychiatric conditions. However, the role of adolescent…”
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Gonadectomy negatively impacts social behavior of adolescent male primates by Richards, A. Brent, Morris, Richard W., Ward, Sarah, Schmitz, Stephanie, Rothmond, Debora A., Noble, Pam L., Woodward, Ruth A., Winslow, James T., Weickert, Cynthia Shannon

“…Social behavior changes dramatically during primate adolescence. However, the extent to which testosterone and other gonadal hormones are necessary for…”
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Successful behavioral strategy to unite mother and infant rhesus monkeys (Macaca mulatta) after cesarean delivery by Ruggiero, Angela M., Novak, Matthew F.S.X., Woodward, Ruth A., Suomi, Stephen J.

“…Developmental studies of pre‐ to postnatal continuities in rhesus monkeys sometimes require infants be reared with their mothers. However, complications during…”
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Effect of tryptophan treatment on self-biting and central nervous system serotonin metabolism in rhesus monkeys (Macaca mulatta) by WELD, K. P, MENCH, J. A, WOODWARD, R. A, BOLESTA, M. S, SUOMI, S. J, HIGLEY, J. D

“…Two studies were conducted to examine the effects of oral L-tryptophan (TRP) supplementation as a treatment for self-injurious behavior (SIB) and to…”
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Genetic diversity of Klebsiella pneumoniae isolates during an outbreak in a nonhuman primate research colony by Gozalo, Alfonso S., Elkins, William R., Lambert, Lynn E., Stock, Frida, Thomas, Marvin L., Woodward, Ruth A.

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Long trimer-immunization interval and appropriate adjuvant reduce immune responses to the soluble HIV-1-envelope trimer base by Duan, Hongying, Corrigan, Angela R., Cheng, Cheng, Biju, Andrea, Gonelli, Christopher A., Olia, Adam S., Teng, I-Ting, Xu, Kai, O’Dell, Sijy, Narpala, Sandeep, Castro, Mike, Serebryannyy, Leonid, Wang, Jennifer, Parchment, Danealle K., Sarfo, Edward K., van Schooten, Jelle, Todd, John-Paul, Wang, Shuishu, Harris, Darcy R., Geng, Hui, Jafari, Alexander J., Woodward, Ruth A., Doria-Rose, Nicole A., Foulds, Kathryn E., McDermott, Adrian B., van Gils, Marit J., Koup, Richard A., Pierson, Theodore C., Kwong, Peter D., Mascola, John R.

“…Soluble ‘SOSIP’-stabilized HIV-1 envelope glycoprotein (Env) trimers elicit dominant antibody responses targeting their glycan-free base regions, potentially…”
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Evaluation of intra-blood brain barrier IgG synthesis rate and blood brain barrier function in normal rhesus monkeys by JORDAN, E. K, WOODWARD, R. A, SHIFERAW, Y, BLACK, J, SAFAR, J

“…In order to evaluate blood brain barrier (BBB) integrity and intra-BBB IgG synthesis under CSF pathologic conditions, it is necessary to establish normal…”
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A comparison of ketamine, ketamine-acepromazine, and tiletamine-zolazepam on various hematologic parameters in rhesus monkeys (Macaca mulatta) by Woodward, R A, Weld, K P

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Hepatic hemosiderosis in common marmosets, Callithrix jacchus: effect of diet on incidence and severity by Miller, G.F, Barnard, D.E, Woodward, R.A, Flynn, B.M, Bulte, J.W.M

“…We examined the effect of dietary iron concentration on the incidence of hepatic hemosiderosis in common marmosets (Callithrix jacchus) and assessed the impact…”
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