Search Results - "Woodward, Jerold"

Antigen Priming with Enantiospecific Cationic Lipid Nanoparticles Induces Potent Antitumor CTL Responses through Novel Induction of a Type I IFN Response by Gandhapudi, Siva K, Ward, Martin, Bush, John Peyton C, Bedu-Addo, Frank, Conn, Greg, Woodward, Jerold G

“…Certain types of cationic lipids have shown promise in cancer immunotherapy, but their mechanism of action is poorly understood. In this study, we describe the…”
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R-DOTAP Cationic Lipid Nanoparticles Outperform Squalene-Based Adjuvant Systems in Elicitation of CD4 T Cells after Recombinant Influenza Hemagglutinin Vaccination by Henson, Thomas R, Richards, Katherine A, Gandhapudi, Siva K, Woodward, Jerold G, Sant, Andrea J

“…It is clear that new approaches are needed to promote broadly protective immunity to viral pathogens, particularly those that are prone to mutation and escape…”
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mPGES1-Dependent Prostaglandin E2 (PGE2) Controls Antigen-Specific Th17 and Th1 Responses by Regulating T Autocrine and Paracrine PGE2 Production by Maseda, Damian, Johnson, Elizabeth M., Nyhoff, Lindsay E., Baron, Bridgette, Kojima, Fumiaki, Wilhelm, Ashley J., Ward, Martin R., Woodward, Jerold G., Brand, David D., Crofford, Leslie J.

“…The integration of inflammatory signals is paramount in controlling the intensity and duration of immune responses. Eicosanoids, particularly PGE2, are…”
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Recombinant Protein Vaccines Formulated with Enantio-Specific Cationic Lipid R-DOTAP Induce Protective Cellular and Antibody-Mediated Immune Responses in Mice by Gandhapudi, Siva K, Shi, Hua, Ward, Martin R, Bush, John Peyton, Avdiushko, Margarita, Sundarapandiyan, Karuna, Wood, Lauren V, Dorrani, Mania, Fatima, Afsheen, Dervan, Joe, Bedu-Addo, Frank, Conn, Greg, Ross, Ted M, Woodward, Jerold G

“…Adjuvants are essential components of subunit vaccines added to enhance immune responses to antigens through immunomodulation. Very few adjuvants have been…”
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Chylomicrons Promote Intestinal Absorption and Systemic Dissemination of Dietary Antigen (Ovalbumin) in Mice by Wang, Yuehui, Ghoshal, Sarbani, Ward, Martin, De Villiers, Willem, Woodward, Jerold, Eckhardt, Erik

“…Background: A small fraction of dietary protein survives enzymatic degradation and is absorbed in potentially antigenic form. This can trigger inflammatory…”
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Reduced T cell-dependent humoral immune response in microsomal prostaglandin E synthase-1 null mice is mediated by nonhematopoietic cells by Kojima, Fumiaki, Frolov, Andrey, Matnani, Rahul, Woodward, Jerold G, Crofford, Leslie J

“…Microsomal PGE synthase-1 (mPGES-1) is an inducible enzyme that specifically catalyzes the conversion of PGH2 to PGE2. We showed that mPGES-1 null mice had a…”
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Lipid nanocapsule as vaccine carriers for his-tagged proteins: Evaluation of antigen-specific immune responses to HIV I His-Gag p41 and systemic inflammatory responses by Wadhwa, Saurabh, Jain, Anekant, Woodward, Jerold G., Mumper, Russell J.

“…Histidine-tagged HIV I Gag p41 bound to lipid based nanocapsules through interaction with surface accessible nickel generated a strong dose-dependent immune…”
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Dietary medium-chain triglycerides promote oral allergic sensitization and orally induced anaphylaxis to peanut protein in mice by Li, Jianing, MS, Wang, Yu, BS, Tang, Lihua, PhD, de Villiers, Willem J.S., MD, PhD, Cohen, Donald, PhD, Woodward, Jerold, PhD, Finkelman, Fred D., MD, Eckhardt, Erik R.M., PhD

“…Background The prevalence of peanut allergies is increasing. Peanuts and many other allergen sources contain significant amounts of triglycerides, which affect…”
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Preparation and characterization of nickel nanoparticles for binding to his-tag proteins and antigens by PATEL, Jigna D, O'CARRA, Ronan, JONES, Julia, WOODWARD, Jerold G, MUMPER, Russell J

“…The purpose of these studies was to prepare nanoparticles (NPs) with a small amount of surface-chelated nickel for obtaining enhanced binding of…”
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Heat shock transcription factor 1 is activated as a consequence of lymphocyte activation and regulates a major proteostasis network in T cells critical for cell division during stress by Gandhapudi, Siva K, Murapa, Patience, Threlkeld, Zachary D, Ward, Martin, Sarge, Kevin D, Snow, Charles, Woodward, Jerold G

“…Heat shock transcription factor 1 (HSF1) is a major transcriptional regulator of the heat shock response in eukaryotic cells. HSF1 is evoked in response to a…”
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Heat Shock Factor 1 Protects Mice from Rapid Death during Listeria monocytogenes Infection by Regulating Expression of Tumor Necrosis Factor Alpha during Fever by Murapa, Patience, Ward, Martin R, Gandhapudi, Siva K, Woodward, Jerold G, D'Orazio, Sarah E F

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Immunologic profiles of red blood cells using in vitro models of transfusion by Long, Kristin, MD, Meier, Cindy, MS, Ward, Martin, MS, Williams, Dennis, MD, Woodward, Jerold, PhD, Bernard, Andrew, MD

“…Abstract Background Transfusion of packed red blood cells (RBCs) produces a myriad of immunologic derangements, from suppressive to stimulatory. Proliferation…”
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Defective Generation of a Humoral Immune Response Is Associated with a Reduced Incidence and Severity of Collagen-Induced Arthritis in Microsomal Prostaglandin E Synthase-1 Null Mice by Kojima, Fumiaki, Kapoor, Mohit, Yang, Lihua, Fleishaker, Erica L, Ward, Martin R, Monrad, Seetha U, Kottangada, Ponnappa C, Pace, Charles Q, Clark, James A, Woodward, Jerold G, Crofford, Leslie J

“…Microsomal PGE synthase-1 (mPGES-1) is an inducible enzyme that acts downstream of cyclooxygenase and specifically catalyzes the conversion of PGH(2) to…”
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Tresyl-based conjugation of protein antigen to lipid nanoparticles increases antigen immunogenicity by Jain, Anekant, Yan, Weili, Miller, Keith R., O’Carra, Ronan, Woodward, Jerold G., Mumper, Russell J.

“…The present studies were aimed at investigating the engineering of NPs with protein-conjugated-surfactant at their surface. In order to increase the…”
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Physiological Fever Temperature Induces a Protective Stress Response in T Lymphocytes Mediated by Heat Shock Factor-1 (HSF1) by Murapa, Patience, Gandhapudi, Siva, Skaggs, Hollie S, Sarge, Kevin D, Woodward, Jerold G

“…Heat shock factor-1 (HSF1) is a transcription factor that serves as the major temperature-inducible sensor for eukaryotic cells. In most cell types, HSF1…”
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y+ cationic amino acid transport of arginine in packed red blood cells by Procter, Levi D., MD, Meier, Cindy F., MS, Hamilton, Cameron, Gerughty, Andrew R, Overall, Philip, MD, Santapuram, Pranav, Davenport, Daniel L., PhD, McNamara, Patrick, PhD, Woodward, Jerold, PhD, Bernard, Andrew C., MD

“…Abstract Background Transfusion of packed red blood cells (PRBCs) is associated with morbidity and mortality. The mechanisms are not fully understood. Packed…”
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Correction: Chylomicrons Promote Intestinal Absorption and Systemic Dissemination of Dietary Antigen (Ovalbumin) in Mice by Wang, Yuehui, Ghoshal, Sarbani, Ward, Martin, de Villiers, Willem, Woodward, Jerold, Eckhardt, Erik

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505 Chylomicron Formation Promotes Oral Tolerance By Promoting Intestinal Absorption and Lymphatic Transport of Dietary Protein by Wang, Yuehui, Ghoshal, Sarbani, de Villiers, Willem J, Woodward, Jerold G, Eckhardt, Erik

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Strong T cell type-1 immune responses to HIV-1 Tat (1–72) protein-coated nanoparticles by Cui, Zhengrong, Patel, Jigna, Tuzova, Marina, Ray, Phillip, Phillips, Ryan, Woodward, Jerold G., Nath, Avindra, Mumper, Russell J.

“…A significant emphasis has been placed on the development of adjuvants and/or delivery systems to improve both antibody production and cell-mediated immune…”
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M1678 Chylomicron Formation Enhances Absorption of Intestinal Luminal Antigens Into Mesenteric Lymph Nodes and Blood by Ghoshal, Sarbani, Woodward, Jerold G, Witta, Jassir, de Villiers, Willem J, Eckhardt, Erik

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