Search Results - "Woodward, D.F"

The pharmacology and therapeutic relevance of endocannabinoid derived cyclo-oxygenase (COX)-2 products by Woodward, D F, Carling, R W C, Cornell, C L, Fliri, H G, Martos, J L, Pettit, S N, Liang, Y, Wang, J W

“…The discovery of anandamide and 2-arachidonyl glycerol (2-AG) as naturally occurring mammalian endocannabinoids has had important and wide-reaching therapeutic…”
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Immunohistochemical demonstration of increased prostaglandin F2α levels in the rat hippocampus following kainic acid-induced seizures by Takei, S, Hasegawa-Ishii, S, Uekawa, A, Chiba, Y, Umegaki, H, Hosokawa, M, Woodward, D.F, Watanabe, K, Shimada, A

“…Highlights ► Precise immunohistological localization of PGs was achieved by carbodiimide fixation. ► Systemic excitotoxin injection elevated PGF2α levels in…”
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72. Immunohistochemical demonstration of enhanced prostaglandin F2alpha production following kainic acid-induced seizures in rat hippocampus by Takei, S, Hasegawa-Ishii, S, Woodward, D.F, Watanabe, K, Shimada, A

“…Prostaglandin (PG) F2alpha is one of the major prostanoids biosynthesized from arachidonic acid and catalyzed by cyclooxygenases (COXs). PGF2alpha exerts…”
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The Pharmacology of Bimatoprost (Lumigan™) by Woodward, D.F, Krauss, A.H.-P, Chen, J, Lai, R.K, Spada, C.S, Burk, R.M, Andrews, S.W, Shi, L, Liang, Y, Kedzie, K.M, Chen, R, Gil, D.W, Kharlamb, A, Archeampong, A, Ling, J, Madhu, C, Ni, J, Rix, P, Usansky, J, Usansky, H, Weber, A, Welty, D, Yang, W, Tang-Liu, D.D.-S, Garst, M.E, Brar, B, Wheeler, L.A, Kaplan, L.J

“…Bimatoprost (Lumigan™) is a pharmacologically unique and highly efficacious ocular hypotensive agent. It appears to mimic the activity of a newly discovered…”
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Lipidomic analysis reveals prostanoid profiles in human term pregnant myometrium by Durn, J.H, Marshall, K.M, Farrar, D, O’Donovan, P, Scally, A.J, Woodward, D.F, Nicolaou, A

“…Abstract Prostanoids modulate the activity of human pregnant myometrium and their functional role can be appreciated through characterisation of prostanoid…”
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Analysis of prostaglandin receptor subtype expression and primary prostanoid release from TNFα and LPS — Stimulated human macrophages and osteoclasts by Wang, J.W, Woodward, D.F, Ross, R.A, Kingsley, P.J, Marnett, L.J

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Endocannabinoids and their oxygenation by cyclo-oxygenases, lipoxygenases and other oxygenases by Urquhart, P., Nicolaou, A., Woodward, D.F.

“…The naturally occurring mammalian endocannabinoids possess biological attributes that extend beyond interaction with cannabinoid receptors. These extended…”
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Bimatoprost, Prostamide Activity, and Conventional Drainage by Wan, Zhou, Woodward, David F, Cornell, Clive L, Fliri, Hans G, Martos, Jose L, Pettit, Simon N, Wang, Jenny W, Kharlamb, Alexander B, Wheeler, Larry A, Garst, Michael E, Landsverk, Kari J, Struble, Craig S, Stamer, W. Daniel

“…Despite structural similarity with prostaglandin F(2 alpha), the ocular hypotensive agent bimatoprost (Lumigan; Allergan, Inc., Irvine, CA) shows unique…”
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Characterization of an in vivo model for the study of eyelash biology and trichomegaly: mouse eyelash morphology, development, growth cycle, and anagen prolongation by bimatoprost by Tauchi, M., Fuchs, T.A., Kellenberger, A.J., Woodward, D.F., Paus, R., Lütjen-Drecoll, E.

“…Summary Background  Hypertrichosis or alopecia of the eyelashes is associated with various diseases or may be drug induced. Although neither increase nor loss…”
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Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration by Matias, I., Wang, J.W., Moriello, A. Schiano, Nieves, A., Woodward, D.F., Di Marzo, V.

“…Cannabinoid receptors and the endocannabinoids (anandamide ( N-arachidonoylethanolamine—AEA) and 2-arachidonoylglycerol (2-AG)), as well as the AEA congener,…”
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Characterization of an in vivo model for the study of eyelash biology and trichomegaly: mouse eyelash morphology, development, growth cycle, and anagen prolongation by bimatoprost: Characterization of mouse eyelashes as a study model by Tauchi, M., Fuchs, T.A., Kellenberger, A.J., Woodward, D.F., Paus, R., Lütjen-Drecoll, E.

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Comparison of leukotriene B4 and D4 effects on human eosinophil and neutrophil motility in vitro by Spada, C S, Nieves, A L, Krauss, A H, Woodward, D F

“…The motility of isolated normal human peripheral blood eosinophils and neutrophils in response to exogenous leukotrienes B4 and D4 was examined by means of a…”
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Cloning of a carboxyl-terminal isoform of the prostanoid FP receptor by Pierce, K.L, Bailey, T.J, Hoyer, P.B, Gil, D.W, Woodward, D.F, Regan, J.W

“…An FP prostanoid receptor isoform, which appears to arise from alternative mRNA splicing, has been cloned from a mid-cycle ovine large cell corpus luteum…”
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Identification of 19 (R)-OH prostaglandin E2 as a selective prostanoid EP2-receptor agonist by Woodward, D F, Protzman, C E, Krauss, A H, Williams, L S

“…The physiological significance of the formation of large quantities of 19(R)-hydroxy prostaglandin E's (19-OH PGE) from PGE1 and PGE2 in human seminal plasma…”
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Latanoprost-induced pigmentation in human iridial melanocytes is fibroblast dependent by Smith-Thomas, L, Moustafa, M, Spada, C.S, Shi, L, Dawson, R.A, Wagner, M, Balafa, C, Kedzie, K.M, Reagan, J.W, Krauss, A.H.-P, Woodward, D.F, MacNeil, S

“…The prostaglandin F2α derivative, latanoprost (LT), used in glaucoma treatment, can induce pigmentation in irises of patients with hazel or heterochromatic eye…”
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Molecular cloning and expression of human EP3 receptors: evidence of three variants with differing carboxyl termini by Regan, J.W., Bailey, T.J., Donello, J.E., Pierce, K.L., Pepperl, D.J., Zhang, D., Kedzie, K.M., Fairbairn, C.E., Bogardus, A.M., Woodward, D.F., Gil, D.W.

“…1 The polymerase chain reaction (PCR) was used in combination with plaque hybridization analysis to clone four variants of the EP3 prostaglandin receptor from…”
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Identification of a prostanoid FP receptor population producing endothelium‐dependent vasorelaxation in the rabbit jugular vein by Chen, J., Champa‐Rodriguez, M.L., Woodward, D.F.

“…1 Prostaglandin F2α (PGF2α) and its synthetic analogue, fluprostenol, potently relaxed the precontracted isolated jugular vein of the rabbit (RJuV). The…”
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Relationships between boron concentrations and trout in the Firehole River, Wyoming by Meyer, J.S, Boelter, A.M, Woodward, D.F, Goldstein, J.N, Farag, A.M, Hubert, W.A

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An EP receptor with a novel pharmacological profile in the T‐cell line Jurkat by Vries, G.W., Guarino, P., McLaughlin, A., Chen, J., Andrews, S., Woodward, D.F.

“…1 Comparison of the rank order of potency of the natural prostanoids prostaglandin E2 (PGE2), PGD2, PGF2a and carbaprostacyclin in stimulating cyclic AMP in…”
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Toxicity of five forest insecticide to cutthroat trout and two species of aquatic invertebrates by Woodward, D.F, Mauck, W.L

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