Search Results - "Woods, Laura"

Regulation of Placental Development and Its Impact on Fetal Growth-New Insights From Mouse Models by Woods, Laura, Perez-Garcia, Vicente, Hemberger, Myriam

“…The placenta is the chief regulator of nutrient supply to the growing embryo during gestation. As such, adequate placental function is instrumental for…”
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Can we screen for pancreatic cancer? Identifying a sub-population of patients at high risk of subsequent diagnosis using machine learning techniques applied to primary care data by Malhotra, Ananya, Rachet, Bernard, Bonaventure, Audrey, Pereira, Stephen P, Woods, Laura M

“…Pancreatic cancer (PC) represents a substantial public health burden. Pancreatic cancer patients have very low survival due to the difficulty of identifying…”
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Risk factors for early-onset pancreatic ductal adenocarcinoma: A systematic literature review by Chandana, Sreenivasa R., Woods, Laura M., Maxwell, Fiona, Gandolfo, Ruth, Bekaii-Saab, Tanios

“…Emerging cancer trends suggest an increase in pancreatic cancer incidence in individuals younger than its typical age of onset, potentially reflecting changes…”
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Horizontal gene transfer potentiates adaptation by reducing selective constraints on the spread of genetic variation by Woods, Laura C., Gorrell, Rebecca J., Taylor, Frank, Connallon, Tim, Kwok, Terry, McDonald, Michael J.

“…Horizontal gene transfer (HGT) confers the rapid acquisition of novel traits and is pervasive throughout microbial evolution. Despite the central role of HGT,…”
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Diverse hydrogen production and consumption pathways influence methane production in ruminants by Greening, Chris, Geier, Renae, Wang, Cecilia, Woods, Laura C., Morales, Sergio E., McDonald, Michael J., Rushton-Green, Rowena, Morgan, Xochitl C., Koike, Satoshi, Leahy, Sinead C., Kelly, William J., Cann, Isaac, Attwood, Graeme T., Cook, Gregory M., Mackie, Roderick I.

“…Farmed ruminants are the largest source of anthropogenic methane emissions globally. The methanogenic archaea responsible for these emissions use molecular…”
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Decidualisation and placentation defects are a major cause of age-related reproductive decline by Woods, Laura, Perez-Garcia, Vicente, Kieckbusch, Jens, Wang, Xiaoqiu, DeMayo, Francesco, Colucci, Francesco, Hemberger, Myriam

“…Mammalian reproductive performance declines rapidly with advanced maternal age. This effect is largely attributed to the exponential increase in chromosome…”
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Corrigendum to “Risk factors for early-onset pancreatic ductal adenocarcinoma: A systematic literature review” [Eur J Cancer 198 (2024) 113471] by Chandana, Sreenivasa R., Woods, Laura M., Maxwell, Fiona, Gandolfo, Ruth, Bekaii-Saab, Tanios

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Cancer incidence, survival and mortality: Explaining the concepts by Ellis, Libby, Woods, Laura M., Estève, Jacques, Eloranta, Sandra, Coleman, Michel P., Rachet, Bernard

“…Cancer incidence, survival and mortality are essential population‐based indicators for public health and cancer control. Confusion and misunderstanding still…”
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Recombination resolves the cost of horizontal gene transfer in experimental populations of Helicobacter pylori by Nguyen, An N T, Woods, Laura C, Gorrell, Rebecca, Ramanan, Shamitraa, Kwok, Terry, McDonald, Michael J

“…Horizontal gene transfer (HGT) is important for microbial evolution, yet we know little about the fitness effects and dynamics of horizontally transferred…”
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Estimation of net survival for cancer patients: Relative survival setting more robust to some assumption violations than cause-specific setting, a sensitivity analysis on empirical data by Schaffar, Robin, Rachet, Bernard, Belot, Aurélien, Woods, Laura M

“…Abstract Net survival is the survival that would be observed if the only possible underlying cause of death was the disease under study. It can be estimated…”
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Horizontal Gene Transfer, Fitness Costs and Mobility Shape the Spread of Antibiotic Resistance Genes into Experimental Populations of Acinetobacter Baylyi by Sezmis, Aysha L, Woods, Laura C, Peleg, Anton Y, McDonald, Michael J

“…Abstract Horizontal gene transfer (HGT) is important for microbial evolution, but how evolutionary forces shape the frequencies of horizontally transferred…”
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An investigation of cancer survival inequalities associated with individual-level socio-economic status, area-level deprivation, and contextual effects, in a cancer patient cohort in England and Wales by Ingleby, Fiona C, Woods, Laura M, Atherton, Iain M, Baker, Matthew, Elliss-Brookes, Lucy, Belot, Aurélien

“…People living in more deprived areas of high-income countries have lower cancer survival than those in less deprived areas. However, associations between…”
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Assessment of the concordance between individual-level and area-level measures of socio-economic deprivation in a cancer patient cohort in England and Wales by Ingleby, Fiona C, Belot, Aurélien, Atherton, Iain, Baker, Matthew, Elliss-Brookes, Lucy, Woods, Laura M

“…ObjectivesMost research on health inequalities uses aggregated deprivation scores assigned to the small area where the patient lives; however, the concordance…”
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Elevated ASCL1 activity creates de novo regulatory elements associated with neuronal differentiation by Woods, Laura M, Ali, Fahad R, Gomez, Roshna, Chernukhin, Igor, Marcos, Daniel, Parkinson, Lydia M, Tayoun, Ahmad N Abou, Carroll, Jason S, Philpott, Anna

“…The pro-neural transcription factor ASCL1 is a master regulator of neurogenesis and a key factor necessary for the reprogramming of permissive cell types to…”
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Bacteriophages evolve enhanced persistence to a mucosal surface by Chin, Wai Hoe, Kett, Ciaren, Cooper, Oren, Müseler, Deike, Zhang, Yaqi, Bamert, Rebecca S, Patwa, Ruzeen, Woods, Laura C, Devendran, Citsabehsan, Korneev, Denis, Tiralongo, Joe, Lithgow, Trevor, McDonald, Michael J, Neild, Adrian, Barr, Jeremy J

“…The majority of viruses within the gut are obligate bacterial viruses known as bacteriophages (phages). Their bacteriotropism underscores the study of phage…”
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A novel ecological methodology for constructing ethnic-majority life tables in the absence of individual ethnicity information by Morris, Melanie, Woods, Laura M, Rachet, Bernard

“…Background Deprivation-specific life tables have been in use for some time, but health outcomes are also known to vary by ethnicity over and above deprivation…”
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Clearance of senescent decidual cells by uterine natural killer cells in cycling human endometrium by Brighton, Paul J, Maruyama, Yojiro, Fishwick, Katherine, Vrljicak, Pavle, Tewary, Shreeya, Fujihara, Risa, Muter, Joanne, Lucas, Emma S, Yamada, Taihei, Woods, Laura, Lucciola, Raffaella, Hou Lee, Yie, Takeda, Satoru, Ott, Sascha, Hemberger, Myriam, Quenby, Siobhan, Brosens, Jan Joris

“…In cycling human endometrium, menstruation is followed by rapid estrogen-dependent growth. Upon ovulation, progesterone and rising cellular cAMP levels…”
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Multivariable flexible modelling for estimating complete, smoothed life tables for sub-national populations by Rachet, Bernard, Maringe, Camille, Woods, Laura M, Ellis, Libby, Spika, Devon, Allemani, Claudia

“…The methods currently available to estimate age- and sex-specific mortality rates for sub-populations are subject to a number of important limitations. We…”
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Species interactions constrain adaptation and preserve ecological stability in an experimental microbial community by Barber, Jake N., Nicholson, Luke C., Woods, Laura C., Judd, Louise M., Sezmis, Aysha L., Hawkey, Jane, Holt, Kathryn E., McDonald, Michael J.

“…Species loss within a microbial community can increase resource availability and spur adaptive evolution. Environmental shifts that cause species loss or…”
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Population-based cancer survival trends in England and Wales up to 2007: an assessment of the NHS cancer plan for England by Rachet, Bernard, MD, Maringe, Camille, MSc, Nur, Ula, PhD, Quaresma, Manuela, MSc, Shah, Anjali, PhD, Woods, Laura M, PhD, Ellis, Libby, MPH, Walters, Sarah, MSc, Forman, David, Prof, Steward, John, FFPH, Coleman, Michel P, Prof

“…Summary Background The National Health Service (NHS) cancer plan for England was published in 2000, with the aim of improving the survival of patients with…”
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