Search Results - "Woods, James M"

The vascular endothelium as a target of cadmium toxicity by Prozialeck, Walter C., Edwards, Joshua R., Woods, James M.

“…Cadmium (Cd) is an important industrial and environmental pollutant that can produce a wide variety of adverse effects in humans and animals. A growing volume…”
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Inhibition of Monocyte Chemoattractant Protein-1 Ameliorates Rat Adjuvant-Induced Arthritis by Shahrara, Shiva, Proudfoot, Amanda E. I, Park, Christy C, Volin, Michael V, Haines, G. Kenneth, Woods, James M, Aikens, Christopher H, Handel, Tracy M, Pope, Richard M

“…Chemokines, including RANTES/CCL5 and MCP-1/CCL2, are highly expressed in the joints of patients with rheumatoid arthritis, and they promote leukocyte…”
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Migration Inhibitory Factor Mediates Angiogenesis via Mitogen-Activated Protein Kinase and Phosphatidylinositol Kinase by Amin, M Asif, Volpert, Olga V, Woods, James M, Kumar, Pawan, Harlow, Lisa A, Koch, Alisa E

“…ABSTRACT—In this study, we investigated the effects of migration inhibitory factor (rhMIF) on angiogenesis-related signaling cascades and apoptosis in human…”
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Fractalkine: A Novel Angiogenic Chemokine in Rheumatoid Arthritis by Volin, Michael V., Woods, James M., Amin, M. Asif, Connors, Matthew A., Harlow, Lisa A., Koch, Alisa E.

“…Angiogenesis is an important aspect of the vasculoproliferation found in the rheumatoid arthritic (RA) pannus. We have previously implicated members of the CXC…”
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Fractalkine-induced endothelial cell migration requires MAP kinase signaling by Volin, Michael V, Huynh, Nha, Klosowska, Karolina, Reyes, Rosemary D, Woods, James M

“…Angiogenesis is a well-established characteristic in the rheumatoid arthritis (RA) synovial pannus. We have previously demonstrated that fractalkine (Fkn/…”
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The Vascular System as a Target of Metal Toxicity by Prozialeck, Walter C., Edwards, Joshua R., Nebert, Daniel W., Woods, James M., Barchowsky, Aaron, Atchison, William D.

“…Vascular system function involves complex interactions among the vascular endothelium, smooth muscle, the immune system, and the nervous system. The toxic…”
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IL-4 Adenoviral Gene Therapy Reduces Inflammation, Proinflammatory Cytokines, Vascularization, and Bony Destruction in Rat Adjuvant-Induced Arthritis by Woods, James M, Katschke, Kenneth J., Jr, Volin, Michael V, Ruth, Jeffrey H, Woodruff, Drew C, Amin, M. Asif, Connors, Matthew A, Kurata, Hirokazu, Arai, Ken-Ichi, Haines, G. Kenneth, III, Kumar, Pawan, Koch, Alisa E

“…IL-4 is a cytokine with anti-inflammatory properties on activated macrophages. Rheumatoid arthritis, an autoimmune inflammatory disease, is characterized by a…”
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The Civil War Diary of Father James Sheeran, Confederate Chaplain and Redemptorist ed. by Patrick Hayes (review) by Woods, James M

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Anti-Catholicism in America, 1620–1860 by Maura Jane Farrelly (review) by Woods, James M

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The Role of an Epithelial Neutrophil-Activating Peptide-78-Like Protein in Rat Adjuvant-Induced Arthritis by Halloran, Margaret M, Woods, James M, Strieter, Robert M, Szekanecz, Zoltan, Volin, Michael V, Hosaka, Shigeru, Haines, G. Kenneth, III, Kunkel, Steven L, Burdick, Marie D, Walz, Alfred, Koch, Alisa E

“…The chemokine, epithelial neutrophil-activating peptide-78 (ENA-78), is a potent neutrophil chemotaxin whose expression is increased in inflamed synovial…”
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Patrick N. Lynch, 1817–1882: Third Catholic Bishop of Charleston by David C. R. Heisser, and Stephen J. White Sr (review) by Woods, James M

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Sensitization of IFN-γ Jak-STAT signaling during macrophage activation by Ivashkiv, Lionel B, Hu, Xiaoyu, Herrero, Carmen, Li, Wai-Ping, Antoniv, Taras T, Falck-Pedersen, Erik, Koch, Alisa E, Woods, James M, Haines, G. Kenneth

“…A general paradigm in signal transduction is ligand-induced feedback inhibition and the desensitization of signaling. We found that subthreshold concentrations…”
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Modifications in adenoviral coat fiber proteins and transcriptional regulatory sequences enhance transgene expression by PERLMAN, Harris, HONGTAO LIU, POPE, Richard M, GEORGANAS, Constantinos, WOODS, James M, AMIN, M. Asif, KOCH, Alisa E, WICKHAM, Thomas, KOVESDI, Imre, MANO, Toshiaki, WALSH, Kenneth

“…OBJECTIVE: To characterize the adenoviral properties required to enhance intracellular transgene expression for gene therapy. METHODS: Primary human…”
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Synthesis and SAR of sulfoxide substituted carboxyquinolines as NK3 receptor antagonists by Xiong, Hui, Kang, James, Woods, James M., McCauley, John P., Koether, Gerard M., Albert, Jeffrey S., Hinkley, Lindsay, Li, Yan, Gadient, Reto A., Simpson, Thomas R.

“…Synthesis and SAR of a series of C3-alkylsulfoxide substituted quinolines as potent NK3 receptor antagonists are reported. These compounds have excellent NK3…”
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4-Aryl piperazine and piperidine amides as novel mGluR5 positive allosteric modulators by Xiong, Hui, Brugel, Todd A., Balestra, Michael, Brown, Dean G., Brush, Kelly A., Hightower, Caprice, Hinkley, Lindsay, Hoesch, Valerie, Kang, James, Koether, Gerard M., McCauley, John P., McLaren, Francis M., Panko, Laura M., Simpson, Thomas R., Smith, Reed W., Woods, James M., Brockel, Becky, Chhajlani, Vijay, Gadient, Reto A., Spear, Nathan, Sygowski, Linda A., Zhang, Minli, Arora, Jalaj, Breysse, Nathalie, Wilson, Julie M., Isaac, Methvin, Slassi, Abdelmalik, King, Megan M.

“…Positive allosteric modulation of metabotropic glutamate receptor 5 (mGluR5) is regarded as a potential novel treatment for schizophrenic patients. Herein we…”
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Gene therapy for rheumatoid arthritis: recent advances by Woods, James M, Sitabkhan, Yasmin, Koch, Alisa E

“…The treatment of rheumatoid arthritis (RA) in the last decade has made enormous advances with the use of biological therapies. However, these therapies have…”
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Fractalkine is a novel chemoattractant for rheumatoid arthritis fibroblast‐like synoviocyte signaling through MAP kinases and Akt by Volin, Michael V., Huynh, Nha, Klosowska, Karolina, Chong, Kyle K., Woods, James M.

“…Objective Fibroblast‐like synoviocytes (FLS) are a major constituent of the hyperplastic synovial pannus that aggressively invades cartilage and bone during…”
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A cell-cycle independent role for p21 in regulating synovial fibroblast migration in rheumatoid arthritis by Woods, James M, Klosowska, Karolina, Spoden, Darrin J, Stumbo, Nataliya G, Paige, Douglas J, Scatizzi, John C, Volin, Michael V, Rao, Malathi S, Perlman, Harris

“…Rheumatoid arthritis (RA) is characterized by synovial hyperplasia and destruction of cartilage and bone. The fibroblast-like synoviocyte (FLS) population is…”
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The role of COX-2 in angiogenesis and rheumatoid arthritis by Woods, James M, Mogollon, Andres, Amin, Mohammad A, Martinez, Rita J, Koch, Alisa E

“…Recent evidence suggests that cyclooxygenase (COX)-2 is a mediator of angiogenesis, and COX-2 activity is known to be upregulated in the rheumatoid arthritis…”
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In vivo inhibition of angiogenesis by interleukin‐13 gene therapy in a rat model of rheumatoid arthritis by Haas, Christian S., Amin, M. Asif, Ruth, Jeffrey H., Allen, Brittany L., Ahmed, Salahuddin, Pakozdi, Angela, Woods, James M., Shahrara, Shiva, Koch, Alisa E.

“…Objective Interleukin‐13 (IL‐13) is a pleiotropic cytokine that can affect vessel formation, an important component of the rheumatoid arthritis (RA) synovial…”
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