Search Results - "Woods, Brian P"
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Nickel-Catalyzed Enantioselective Reductive Cross-Coupling of Styrenyl Aziridines
Published in Journal of the American Chemical Society (26-04-2017)“…A Ni-catalyzed reductive cross-coupling of styrenyl aziridines with aryl iodides is reported. This reaction proceeds by a stereoconvergent mechanism and is…”
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Benzocyclobutadienes: An Unusual Mode of Access Reveals Unusual Modes of Reactivity
Published in Angewandte Chemie International Edition (26-07-2018)“…The reaction of an aryne with an alkyne to generate a benzocyclobutadiene (BCB) intermediate is rare. We report here examples of this reaction, revealed by…”
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Mechanism of the Intramolecular Hexadehydro-Diels–Alder Reaction
Published in Journal of organic chemistry (04-12-2015)“…Theoretical analysis of the mechanism of the intramolecular hexadehydro-Diels–Alder (HDDA) reaction, validated against prior and newly measured kinetic data…”
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Differential Scanning Calorimetry (DSC) as a Tool for Probing the Reactivity of Polyynes Relevant to Hexadehydro-Diels–Alder (HDDA) Cascades
Published in Organic letters (19-12-2014)“…The differential scanning calorimetry (DSC) behavior of a number of alkyne-rich compounds is described. The DSC trace for each compound exhibits an exothermic…”
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Synthesis of complex benzenoids via the intermediate generation of o-benzynes through the hexadehydro-Diels-Alder reaction
Published in Nature protocols (01-03-2013)“…The hexadehydro-Diels-Alder (HDDA) cascade enables the synthesis of complex benzenoid products with various substitution patterns through aryne intermediates…”
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Organic Synthesis: When and WhyAn Entrepreneurial-Minded Learning Activity for Organic Chemistry Undergraduates
Published in Journal of chemical education (14-05-2024)“…In this in-class activity, organic chemistry undergraduates try to place an assortment of molecules in chronological order from oldest to most recently…”
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The hexadehydro-Diels–Alder reaction
Published in Nature (London) (11-10-2012)“…Arynes (aromatic systems containing, formally, a carbon–carbon triple bond) are among the most versatile of all reactive intermediates in organic chemistry…”
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Alkane desaturation by concerted double hydrogen atom transfer to benzyne
Published in Nature (London) (26-09-2013)“…Benzynes are capable of concerted removal of two vicinal hydrogen atoms from a hydrocarbon, a discovery enabled by the thermal generation of reactive benzyne…”
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An Office-Space Lightboard Studio for Creating Professional Pre-Lecture Videos with Increased Student Engagement
Published in Journal of chemical education (12-09-2023)“…This report offers technical guidance and encouragement for any instructor or department looking to produce valuable, high-quality Lightboard teaching videos…”
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10
Rates of Hexadehydro-Diels–Alder (HDDA) Cyclizations: Impact of the Linker Structure
Published in Organic letters (05-09-2014)“…The rates of the hexadehydro-Diels–Alder (HDDA) reaction of substrates containing, minimally, a 1,3,8-triyne subunit are reported. Several series of related…”
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Dichlorination of (Hexadehydro-Diels–Alder Generated) Benzynes and a Protocol for Interrogating the Kinetic Order of Bimolecular Aryne Trapping Reactions
Published in Organic letters (03-01-2014)“…The efficient dichlorination of benzynes prepared by the hexadehydro-Diels–Alder (HDDA) reaction is reported. Cycloisomerization of a triyne substrate in the…”
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Correction to “Nickel-Catalyzed Enantioselective Reductive Cross-Coupling of Styrenyl Aziridines”
Published in Journal of the American Chemical Society (20-06-2018)Get full text
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Benzocyclobutadienes: An Unusual Mode of Access Reveals Unusual Modes of Reactivity
Published in Angewandte Chemie (26-07-2018)“…The reaction of an aryne with an alkyne to generate a benzocyclobutadiene (BCB) intermediate is rare. We report here examples of this reaction, revealed by…”
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Alkylation of 2-Substituted (6-Methyl-2-pyridyl)methyllithium Species with Epoxides
Published in Journal of organic chemistry (06-02-2009)“…Substituted (6-methyl-2-pyridyl)methyllithium species were reacted with 1,2-epoxyoctane and 2-methyl-2,3-epoxynonane. The monosubstituted epoxide reacted…”
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15
Alkane Desaturation via Concerted Double Hydrogen Atom Transfer to Benzyne
Published in Nature (London) (26-09-2013)Get full text
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16
Some observations on the preparation of platelet-rich plasma
Published in Thrombosis and haemostasis (01-01-1976)“…In order to prepare platelet-rich plasma a constant height and volume of citrated whole blood was centrifuged at different gravity forces and times. The…”
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