Search Results - "Woodrum, Chelsey"

Multicenter phase 2 trial of sirolimus for tuberous sclerosis: kidney angiomyolipomas and other tumors regress and VEGF- D levels decrease by Dabora, Sandra L, Franz, David Neal, Ashwal, Stephen, Sagalowsky, Arthur, DiMario, Jr, Francis J, Miles, Daniel, Cutler, Drew, Krueger, Darcy, Uppot, Raul N, Rabenou, Rahmin, Camposano, Susana, Paolini, Jan, Fennessy, Fiona, Lee, Nancy, Woodrum, Chelsey, Manola, Judith, Garber, Judy, Thiele, Elizabeth A

“…Tuberous sclerosis (TSC) related tumors are characterized by constitutively activated mTOR signaling due to mutations in TSC1 or TSC2. We completed a phase 2…”
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Comparison of three rapamycin dosing schedules in A/J Tsc2+/- mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice with subcutaneous tuberous sclerosis related tumors by Woodrum, Chelsey, Nobil, Alison, Dabora, Sandra L

“…Tuberous Sclerosis Complex (TSC) is an autosomal dominant tumor disorder characterized by the growth of hamartomas in various organs including the kidney,…”
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Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models by Lee, Nancy, Woodrum, Chelsey L, Nobil, Alison M, Rauktys, Aubrey E, Messina, Michael P, Dabora, Sandra L

“…Tuberous sclerosis complex (TSC) is an autosomal dominant tumor suppressor syndrome, characterized by hamartomatous growths in the brain, skin, kidneys, lungs,…”
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Comparison of three rapamycin dosing schedules in A/J Tsc2 .sup.+/- .sup.mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice with subcutaneous tuberous sclerosis related tumors by Woodrum, Chelsey, Nobil, Alison, Dabora, Sandra L

“…Background Tuberous Sclerosis Complex (TSC) is an autosomal dominant tumor disorder characterized by the growth of hamartomas in various organs including the…”
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