Search Results - "Woodrow, D"
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Real-time environmental surveillance of SARS-CoV-2 aerosols
Published in Nature communications (10-07-2023)“…Real-time surveillance of airborne SARS-CoV-2 virus is a technological gap that has eluded the scientific community since the beginning of the COVID-19…”
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Contemporary Cardiac Issues in Duchenne Muscular Dystrophy
Published in Circulation (New York, N.Y.) (05-05-2015)Get full text
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Human Genetics of Hypoplastic Left Heart Syndrome
Published in Advances in experimental medicine and biology (2024)“…Hypoplastic left heart syndrome (HLHS) is a severe congenital cardiovascular malformation characterized by hypoplasia of the left ventricle, aorta, and other…”
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Extracellular Matrix Remodeling and Organization in Developing and Diseased Aortic Valves
Published in Circulation research (09-06-2006)“…Heart valve disease is an important cause of morbidity and mortality worldwide. Little is known about valve disease pathogenesis, but increasing evidence…”
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Comparison of Magnetic Resonance Feature Tracking for Strain Calculation With Harmonic Phase Imaging Analysis
Published in JACC. Cardiovascular imaging (01-02-2010)“…Objectives To compare a steady-state free precession cine sequence–based technique (feature tracking [FT]) to tagged harmonic phase (HARP) analysis for peak…”
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Genetics of Hypoplastic Left Heart Syndrome
Published in The Journal of pediatrics (01-06-2016)Get full text
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Hypoplastic Left Heart Syndrome Links to Chromosomes 10q and 6q and Is Genetically Related to Bicuspid Aortic Valve
Published in Journal of the American College of Cardiology (24-03-2009)“…Objectives This study was designed to identify disease loci for hypoplastic left heart syndrome (HLHS) and evaluate the genetic relationship between HLHS and…”
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Fetal Heart Rate Predictors of Long QT Syndrome
Published in Circulation (New York, N.Y.) (04-12-2012)“…Fetal long QT syndrome (LQTS) is associated with complex arrhythmias including torsades de pointes and 2° atrioventricular block. Sinus bradycardia has also…”
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Bicuspid Aortic Valve: Identifying Knowledge Gaps and Rising to the Challenge From the International Bicuspid Aortic Valve Consortium (BAVCon)
Published in Circulation (New York, N.Y.) (24-06-2014)Get full text
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A Roadmap to Investigate the Genetic Basis of Bicuspid Aortic Valve and its Complications: Insights From the International BAVCon (Bicuspid Aortic Valve Consortium)
Published in Journal of the American College of Cardiology (26-08-2014)“…Bicuspid aortic valve (BAV) is the most common adult congenital heart defect and is found in 0.5% to 2.0% of the general population. The term "BAV" refers to a…”
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Atenolol versus Losartan in Children and Young Adults with Marfan's Syndrome
Published in The New England journal of medicine (27-11-2014)“…In this study, children and young adults with Marfan's syndrome were randomly assigned to receive atenolol or losartan and were followed for 3 years. There was…”
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The complex genetics of hypoplastic left heart syndrome
Published in Nature genetics (01-07-2017)“…Cecilia Lo and colleagues report the recovery of mice with hypoplastic left heart syndrome (HLHS) from a large mutagenesis screen. They find genetic…”
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Deletion of ETS-1, a gene in the Jacobsen syndrome critical region, causes ventricular septal defects and abnormal ventricular morphology in mice
Published in Human molecular genetics (15-02-2010)“…Congenital heart defects comprise the most common form of major birth defects, affecting 0.7% of all newborn infants. Jacobsen syndrome (11q-) is a rare…”
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Calmodulin Mutations Associated With Recurrent Cardiac Arrest in Infants
Published in Circulation (New York, N.Y.) (05-03-2013)“…Life-threatening disorders of heart rhythm may arise during infancy and can result in the sudden and tragic death of a child. We performed exome sequencing on…”
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Inherited Arrhythmias : A national heart, lung, and blood institute and office of rare diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affecting ion channel function
Published in Circulation (13-11-2007)“…The National Heart, Lung, and Blood Institute and Office of Rare Diseases at the National Institutes of Health organized a workshop (September 14 to 15, 2006,…”
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Effect of escitalopram on Aβ levels and plaque load in an Alzheimer mouse model
Published in Neurology (10-11-2020)“…BACKGROUNDSeveral neurotransmitter receptors activate signaling pathways that alter processing of the amyloid precursor protein (APP) into β-amyloid (Aβ)…”
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Hypoplastic Left Heart Syndrome Is Heritable
Published in Journal of the American College of Cardiology (16-10-2007)“…Hypoplastic Left Heart Syndrome Is Heritable Robert B. Hinton, Jr, Lisa J. Martin, Meredith E. Tabangin, Mjaye L. Mazwi, Linda H. Cripe, D. Woodrow Benson…”
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Spectrum of heart disease associated with murine and human GATA4 mutation
Published in Journal of molecular and cellular cardiology (01-12-2007)“…Abstract The transcription factor GATA4 is essential for heart morphogenesis. Heterozygous mutation of GATA4 causes familial septal defects. However, the…”
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Identifying Genetic Modifiers in the Age of Exome: Current Considerations
Published in The Journal of pediatrics (01-10-2019)Get full text
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Fragment-Based Discovery of Bromodomain Inhibitors Part 2: Optimization of Phenylisoxazole Sulfonamides
Published in Journal of medicinal chemistry (26-01-2012)“…Bromodomains are epigenetic reader modules that regulate gene transcription through their recognition of acetyl-lysine modified histone tails. Inhibitors of…”
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