Search Results - "Woodmansee, David"

Proline-Based P,O Ligand/Iridium Complexes as Highly Selective Catalysts: Asymmetric Hydrogenation of Trisubstituted Alkenes by Rageot, Denise, Woodmansee, David H., Pugin, Benoît, Pfaltz, Andreas

“…P,O joins the mix: P,O ligands (L1) form efficient iridium catalysts for the asymmetric hydrogenation of olefins. The proline‐derived ligands lead to high…”
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Light–Dark Adaptation of Channelrhodopsin Involves Photoconversion between the all-trans and 13-cis Retinal Isomers by Bruun, Sara, Stoeppler, Daniel, Keidel, Anke, Kuhlmann, Uwe, Luck, Meike, Diehl, Anne, Geiger, Michel-Andreas, Woodmansee, David, Trauner, Dirk, Hegemann, Peter, Oschkinat, Hartmut, Hildebrandt, Peter, Stehfest, Katja

“…Channelrhodopsins (ChR) are light-gated ion channels of green algae that are widely used to probe the function of neuronal cells with light. Most ChRs show a…”
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Asymmetric Hydrogenation of α,β-Unsaturated Carboxylic Esters with Chiral Iridium N,P Ligand Complexes by Woodmansee, David H., Müller, Marc-André, Tröndlin, Lars, Hörmann, Esther, Pfaltz, Andreas

“…Enantioselective conjugate reduction of a wide range of α,β‐unsaturated carboxylic esters was achieved using chiral Ir N,P complexes as hydrogenation…”
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AzoCholine Enables Optical Control of Alpha 7 Nicotinic Acetylcholine Receptors in Neural Networks by Damijonaitis, Arunas, Broichhagen, Johannes, Urushima, Tatsuya, Hüll, Katharina, Nagpal, Jatin, Laprell, Laura, Schönberger, Matthias, Woodmansee, David H, Rafiq, Amir, Sumser, Martin P, Kummer, Wolfgang, Gottschalk, Alexander, Trauner, Dirk

“…Nicotinic acetylcholine receptors (nAChRs) are essential for cellular communication in higher organisms. Even though a vast pharmacological toolset to study…”
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Crystal structure of (E)-1,2-bis-(4-bromo-2,6-di-fluoro-phen-yl)diazene by Broichhagen, Johannes, Woodmansee, David H, Trauner, Dirk, Mayer, Peter

“…In the crystal, mol-ecules of the centrosymmetric title compound, C12H4Br2F4N2, are linked into strands along [011] by weak C-H⋯F contacts. Furthermore, the…”
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Highly efficient synthesis of fused bicyclic 2,3-diaryl-pyrimidin-4(3 H)-ones via Lewis acid assisted cyclization reaction by Yang, Kunyong, He, Xiaohui, Choi, Ha-soon, Wang, Zhicheng, Woodmansee, David H., Liu, Hong

“…An expedient one-pot synthesis of fused bicyclic 2,3-diaryl-pyrimidin-4(3 H)-ones is described. The key step is a Lewis acid assisted cyclization reaction. An…”
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Synthesis and Crystal Structures of Bis(sulfonamido) Titanium Bis(alkoxide) Complexes:  Mechanistic Implications in the Bis(sulfonamide) Catalyzed Asymmetric Addition of Dialkylzinc Reagents to Aldehydes by Pritchett, Suzy, Woodmansee, David H, Gantzel, Peter, Walsh, Patrick J

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Synthesis and evaluation of arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 3: Heterocyclic P3 by Tully, David C., Liu, Hong, Alper, Phil B., Chatterjee, Arnab K., Epple, Robert, Roberts, Michael J., Williams, Jennifer A., Nguyen, KhanhLinh T., Woodmansee, David H., Tumanut, Christine, Li, Jun, Spraggon, Glen, Chang, Jonathan, Tuntland, Tove, Harris, Jennifer L., Karanewsky, Donald S.

“…A series of N α-2-benzoxazolyl-α-amino acid-(arylaminoethyl)amides were identified as potent, selective, and noncovalent inhibitors of cathepsin S…”
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Synthesis and SAR of arylaminoethyl amides as noncovalent inhibitors of cathepsin S: P3 cyclic ethers by Tully, David C., Liu, Hong, Chatterjee, Arnab K., Alper, Phil B., Epple, Robert, Williams, Jennifer A., Roberts, Michael J., Woodmansee, David H., Masick, Brian T., Tumanut, Christine, Li, Jun, Spraggon, Glen, Hornsby, Michael, Chang, Jonathan, Tuntland, Tove, Hollenbeck, Thomas, Gordon, Perry, Harris, Jennifer L., Karanewsky, Donald S.

“…The synthesis and SAR a series of arylaminoethyl amide cathepsin S inhibitors are reported, focusing on the optimization of P3 and P2 subunits. An X-ray…”
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Arylaminoethyl carbamates as a novel series of potent and selective cathepsin S inhibitors by Tully, David C., Liu, Hong, Chatterjee, Arnab K., Alper, Phil B., Williams, Jennifer A., Roberts, Michael J., Mutnick, Daniel, Woodmansee, David H., Hollenbeck, Thomas, Gordon, Perry, Chang, Jonathan, Tuntland, Tove, Tumanut, Christine, Li, Jun, Harris, Jennifer L., Karanewsky, Donald S.

“…The synthesis and SAR of a novel series of arylaminoethyl carbamates is reported as potent, highly selective, and orally bioavailable noncovalent inhibitors of…”
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Improved methodology for the asymmetric alkylation of aldehydes employing bis(sulfonamide) complexes by Pritchett, Suzy, Woodmansee, David H, Davis, Timothy J, Walsh, Patrick J

“…We report an improved procedure for the asymmetric transfer of alkyl groups from zinc to aldehydes utilizing bis(sulfonamide) ligands. The new methodology is…”
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Optimized Scalable Synthesis of Chiral Iridium Pyridyl‐Phosphinite (Pyridophos) Catalysts by Müller, Marc‐André, Ganić, Adnan, Hörmann, Esther, Kaiser, Stefan, Maywald, Matthias, Roseblade, Stephen J., Schrems, Marcus G., Schumacher, Andreas, Woodmansee, David, Pfaltz, Andreas

“…Iridium catalysts with chiral P,N ligands have greatly enhanced the scope of asymmetric olefin hydrogenation because they do not require a coordinating group…”
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Proline-Based P,OLigand/Iridium Complexes as Highly Selective Catalysts: Asymmetric Hydrogenation of Trisubstituted Alkenes by Rageot, Denise, Woodmansee, David H, Pugin, Benoît, Pfaltz, Andreas

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Asymmetric Hydrogenation of [alpha],[beta]-Unsaturated Carboxylic Esters with Chiral Iridium N,P Ligand Complexes by Woodmansee, David H, Müller, Marc-André, Tröndlin, Lars, Hörmann, Esther, Pfaltz, Andreas

“…Enantioselective conjugate reduction of a wide range of [alpha],[beta]-unsaturated carboxylic esters was achieved using chiral Ir N,P complexes as…”
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α-Iminoenamido Ligands:  A Novel Structure for Transition-Metal Activation by Kim, Young Heui, Kim, Tae Ho, Lee, Bun Yeoul, Woodmansee, David, Bu, Xianhui, Bazan, Guillermo C

“…This communication shows that it is possible to activate nickel complexes containing the α-iminoenamide ligand using B(C6F5)3 or Al(C6F5)3 to generate…”
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Proline-Based P,OLigand/Iridium Complexes as Highly Selective Catalysts: Asymmetric Hydrogenation of Trisubstituted Alkenes by Rageot, Denise, Woodmansee, David H, Pugin, Benoît, Pfaltz, Andreas

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Proline-Based P,O Ligand/Iridium Complexes as Highly Selective Catalysts: Asymmetric Hydrogenation of Trisubstituted Alkenes by Rageot, Denise, Woodmansee, David H., Pugin, Benoît, Pfaltz, Andreas

“…P,O‐Liganden (L1) bilden Iridium‐Katalysatoren für die asymmetrische Hydrierung von Olefinen. Die von Prolin abgeleiteten Liganden führen mit verschiedenen…”
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The Boratacyclooctatetraene Ligand: An Isoelectronic Trianionic Analogue of the Cyclooctatetraene Dianion by Fang, Xiangdong, Woodmansee, David, Bu, Xianhui, Bazan, Guillermo C.

“…Expanding the ring: Acetylene inserts into one of the intracyclic BC bonds of [(C5H5BMe)2Ti(CO)] (1) to yield [(C7H7BMe)(C5H5BMe)Ti], which contains the…”
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The Boratacyclooctatetraene Ligand: An Isoelectronic Trianionic Analogue of the Cyclooctatetraene Dianion by Fang, Xiangdong, Woodmansee, David, Bu, Xianhui, Bazan, Guillermo C.

“…Durch Insertion von Acetylen in eine Ring‐B‐C‐Bindung von [(C5H5BMe)2Ti(CO)] (1) entsteht [(C7H7BMe)(C5H5BMe)Ti]. Dabei wird der formal trianionische…”
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Synthesis of new chiral tetradentate sulfonamide based ligands by Ho, David E., Betancort, Juan M., Woodmansee, David H., Larter, Martin L., Walsh, Patrick J.

“…A two step procedure for the synthesis of chiral tetradentate sulfonamide ligands is reported. The ligands are easily prepared from the corresponding…”
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