Search Results - "Woodman, Andrew"

The Dictyostelium discoideum FimA protein, unlike yeast and plant fimbrins, is regulated by calcium similar to mammalian plastins by Ishida, Hiroaki, Woodman, Andrew G., Kitada, Naoya, Aizawa, Tomoyasu, Vogel, Hans J.

“…Plastins, also known as fimbrins, are highly conserved eukaryotic multidomain proteins that are involved in actin-bundling. They all contain four independently…”
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Maternal ketone supplementation throughout gestation improves neonatal cardiac dysfunction caused by perinatal iron deficiency by Noble, Ronan M N, Soni, Shubham, Liu, Si Ning, Rachid, Jad-Julian, Mast, Heather E, Wiedemeyer, Alyssa, Holody, Claudia D, Mah, Richard, Woodman, Andrew G, Ferdaoussi, Mourad, Lemieux, Helene, Dyck, Jason R B, Bourque, Stephane L

“…Iron deficiency (ID) is common during gestation and in early infancy and has been shown to adversely affect cardiac development and function, which could lead…”
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Maternal Iron Deficiency Alters Trophoblast Differentiation and Placental Development in Rat Pregnancy by Roberts, Hannah, Woodman, Andrew G, Baines, Kelly J, Jeyarajah, Mariyan J, Bourque, Stephane L, Renaud, Stephen J

“…Iron deficiency, which occurs when iron demands chronically exceed intake, is prevalent in pregnant women. Iron deficiency during pregnancy poses major risks…”
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Perinatal iron restriction is associated with changes in neonatal cardiac function and structure in a sex-dependent manner by Noble, Ronan M N, Holody, Claudia D, Woodman, Andrew G, Nie, Chunpeng, Liu, Si Ning, Young, Daniel, Wiedemeyer, Alyssa, Soni, Shubham, Dyck, Jason R B, Graf, Daniel, Eckersley, Luke G, Dufour, Antoine, Bourque, Stephane L

“…Iron deficiency (ID) is common during gestation and in early infancy and can alter developmental trajectories with lasting consequences on cardiovascular…”
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A speed-fidelity trade-off determines the mutation rate and virulence of an RNA virus by Fitzsimmons, William J, Woods, Robert J, McCrone, John T, Woodman, Andrew, Arnold, Jamie J, Yennawar, Madhumita, Evans, Richard, Cameron, Craig E, Lauring, Adam S

“…Mutation rates can evolve through genetic drift, indirect selection due to genetic hitchhiking, or direct selection on the physicochemical cost of high…”
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Imprecise recombinant viruses evolve via a fitness-driven, iterative process of polymerase template-switching events by Bentley, Kirsten, Alnaji, Fadi Ghassan, Woodford, Luke, Jones, Siân, Woodman, Andrew, Evans, David J

“…Recombination is a common feature of many positive-strand RNA viruses, playing an important role in virus evolution. However, to date, there is limited…”
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Recombination in enteroviruses is a biphasic replicative process involving the generation of greater-than genome length 'imprecise' intermediates by Lowry, Kym, Woodman, Andrew, Cook, Jonathan, Evans, David J

“…Recombination in enteroviruses provides an evolutionary mechanism for acquiring extensive regions of novel sequence, is suggested to have a role in genotype…”
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The Calcium-Dependent Switch Helix of L-Plastin Regulates Actin Bundling by Ishida, Hiroaki, Jensen, Katharine V., Woodman, Andrew G., Hyndman, M. Eric, Vogel, Hans J.

“…L-plastin is a calcium-regulated actin-bundling protein that is expressed in cells of hematopoietic origin and in most metastatic cancer cells. These cell…”
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Developmental programming of renal function: nephron endowment and beyond by Woodman, Andrew G., Bourque, Stephane L.

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Single-Cell Virology: On-Chip Investigation of Viral Infection Dynamics by Guo, Feng, Li, Sixing, Caglar, Mehmet Umut, Mao, Zhangming, Liu, Wu, Woodman, Andrew, Arnold, Jamie J., Wilke, Claus O., Huang, Tony Jun, Cameron, Craig E.

“…We have developed a high-throughput, microfluidics-based platform to perform kinetic analysis of viral infections in individual cells. We have analyzed…”
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Perinatal iron deficiency and a high salt diet cause long-term kidney mitochondrial dysfunction and oxidative stress by Woodman, Andrew G, Mah, Richard, Keddie, Danae L, Noble, Ronan M N, Holody, Claudia D, Panahi, Sareh, Gragasin, Ferrante S, Lemieux, Helene, Bourque, Stephane L

“…Abstract Aims Perinatal iron deficiency (ID) alters developmental trajectories of offspring, predisposing them to cardiovascular dysfunction in later life. The…”
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Modest and Severe Maternal Iron Deficiency in Pregnancy are Associated with Fetal Anaemia and Organ-Specific Hypoxia in Rats by Woodman, Andrew G., Care, Alison S., Mansour, Yael, Cherak, Stephana J., Panahi, Sareh, Gragasin, Ferrante S., Bourque, Stephane L.

“…Prenatal iron-deficiency (ID) is known to alter fetal developmental trajectories, which predisposes the offspring to chronic disease in later life, although…”
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Perinatal iron deficiency causes sex-dependent alterations in renal retinoic acid signaling and nephrogenesis by Woodman, Andrew G., Mah, Richard L., Kinney, Samantha, Holody, Claudia D., Wiedemeyer, Alyssa R., Noble, Ronan M.N., Clugston, Robin D., Bourque, Stephane L.

“…Long-term alterations in kidney structure and function have been observed in offspring exposed to perinatal stressors such as iron deficiency (ID), albeit the…”
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Foot-and-mouth disease virus type O specific mutations determine RNA-dependent RNA polymerase fidelity and virus attenuation by Li, Chen, Wang, Haiwei, Yuan, Tiangang, Woodman, Andrew, Yang, Decheng, Zhou, Guohui, Cameron, Craig E., Yu, Li

“…Previous studies have shown that the FMDV Asia1/YS/CHA/05 high-fidelity mutagen-resistant variants are attenuated (Zeng et al., 2014). Here, we introduced the…”
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Perinatal iron deficiency combined with a high salt diet in adulthood causes sex‐dependent vascular dysfunction in rats by Woodman, Andrew G., Noble, Ronan M. N., Panahi, Sareh, Gragasin, Ferrante S., Bourque, Stephane L.

“…Key points Perinatal iron deficiency causes changes in offspring mesenteric artery function in adulthood, particularly in males, which can be exacerbated by…”
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Generated Randomly and Selected Functionally? The Nature of Enterovirus Recombination by Alnaji, Fadi G, Bentley, Kirsten, Pearson, Ashley, Woodman, Andrew, Moore, Jonathan, Fox, Helen, Macadam, Andrew J, Evans, David J

“…Genetic recombination in RNA viruses is an important evolutionary mechanism. It contributes to population diversity, host/tissue adaptation, and compromises…”
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Prenatal iron deficiency causes sex‐dependent mitochondrial dysfunction and oxidative stress in fetal rat kidneys and liver by Woodman, Andrew G., Mah, Richard, Keddie, Danae, Noble, Ronan M. N., Panahi, Sareh, Gragasin, Ferrante S., Lemieux, Hélène, Bourque, Stephane L.

“…ABSTRACT Prenatal iron deficiency alters fetal developmental trajectories, which results in persistent changes in organ function. Here, we studied the effects…”
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A systematic review and meta-analysis of the correlation between maternal and neonatal iron status and haematologic indices by Sanni, Omolara B., Chambers, Thane, Li, Jia Hang, Rowe, Stewart, Woodman, Andrew G., Ospina, Maria B., Bourque, Stephane L.

“…Iron deficiency (ID) is the leading single-nutrient deficiency in the world. Anaemia is a common outcome of ID that affects half of pregnancies worldwide with…”
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Maternal and Cord Blood Hemoglobin as Determinants of Placental Weight: A Cross-Sectional Study by Gragasin, Ferrante S, Ospina, Maria B, Serrano-Lomelin, Jesus, Kim, Su Hwan, Kokotilo, Matthew, Woodman, Andrew G, Renaud, Stephen J, Bourque, Stephane L

“…Both high and low placental weights are associated with adverse pregnancy outcomes. Maternal hemoglobin levels can influence placental weight, but the evidence…”
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Senecavirus-Specific Recombination Assays Reveal the Intimate Link between Polymerase Fidelity and RNA Recombination by Li, Chen, Wang, Haiwei, Shi, Jiabao, Yang, Decheng, Zhou, Guohui, Chang, Jitao, Cameron, Craig E, Woodman, Andrew, Yu, Li

“…Senecavirus A (SVA) is a reemerging virus, and recent evidence has emphasized the importance of SVA recombination on virus evolution. In this study, we report…”
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