Search Results - "Woodle, E."

Development and Validation of a Multiplex, Bead-based Assay to Detect Antibodies Directed Against SARS-CoV-2 Proteins by Bray, Robert A., Lee, Jar-How, Brescia, Peter, Kumar, Deepali, Nong, Thoa, Shih, Remi, Woodle, E. Steve, Maltzman, Jonathan S., Gebel, Howard M.

“…BACKGROUND:Transplant recipients who develop COVID-19 may be at increased risk for morbidity and mortality. Determining the status of antibodies against…”
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Complement-activating donor-specific anti-HLA antibodies and solid organ transplant survival: A systematic review and meta-analysis by Bouquegneau, Antoine, Loheac, Charlotte, Aubert, Olivier, Bouatou, Yassine, Viglietti, Denis, Empana, Jean-Philippe, Ulloa, Camilo, Murad, Mohammad Hassan, Legendre, Christophe, Glotz, Denis, Jackson, Annette M, Zeevi, Adriana, Schaub, Stephan, Taupin, Jean-Luc, Reed, Elaine F, Friedewald, John J, Tyan, Dolly B, Süsal, Caner, Shapiro, Ron, Woodle, E Steve, Hidalgo, Luis G, O'Leary, Jacqueline, Montgomery, Robert A, Kobashigawa, Jon, Jouven, Xavier, Jabre, Patricia, Lefaucheur, Carmen, Loupy, Alexandre

“…Anti-human leukocyte antigen donor-specific antibodies (anti-HLA DSAs) are recognized as a major barrier to patients' access to organ transplantation and the…”
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Malignancy after transplantation by Buell, Joseph F, Gross, Thomas G, Woodle, E Steve

“…As newer immunosuppressive regimens have steadily reduced the incidence of acute rejection and have extended the life expectancy of allograft recipients,…”
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A Steady‐State Head‐to‐Head Pharmacokinetic Comparison of All FK‐506 (Tacrolimus) Formulations (ASTCOFF): An Open‐Label, Prospective, Randomized, Two‐Arm, Three‐Period Crossover Study by Tremblay, S., Nigro, V., Weinberg, J., Woodle, E. S., Alloway, R. R.

“…This two‐sequence, three‐period crossover study is the first pharmacokinetic (PK) study to compare all three innovator formulations of tacrolimus (twice‐daily…”
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The immune cell landscape in kidneys of patients with lupus nephritis by Arazi, Arnon, Rao, Deepak A., Berthier, Celine C., Davidson, Anne, Liu, Yanyan, Hoover, Paul J., Chicoine, Adam, Eisenhaure, Thomas M., Jonsson, A. Helena, Li, Shuqiang, Lieb, David J., Zhang, Fan, Slowikowski, Kamil, Browne, Edward P., Noma, Akiko, Sutherby, Danielle, Steelman, Scott, Smilek, Dawn E., Tosta, Patti, Apruzzese, William, Massarotti, Elena, Dall’Era, Maria, Park, Meyeon, Kamen, Diane L., Furie, Richard A., Payan-Schober, Fernanda, Pendergraft, William F., McInnis, Elizabeth A., Buyon, Jill P., Petri, Michelle A., Putterman, Chaim, Kalunian, Kenneth C., Woodle, E. Steve, Lederer, James A., Hildeman, David A., Nusbaum, Chad, Raychaudhuri, Soumya, Kretzler, Matthias, Anolik, Jennifer H., Brenner, Michael B., Wofsy, David, Hacohen, Nir, Diamond, Betty

“…Lupus nephritis is a potentially fatal autoimmune disease for which the current treatment is ineffective and often toxic. To develop mechanistic hypotheses of…”
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Clinical Implications of Donor Warm and Cold Ischemia Time in Donor After Circulatory Death Liver Transplantation by Paterno, Flavio, Guarrera, James V., Wima, Koffi, Diwan, Tayyab, Cuffy, Madison C., Anwar, Nadeem, Woodle, E. Steve, Shah, Shimul

“…The use of donation after circulatory death (DCD) liver allografts has been constrained by limitations in the duration of donor warm ischemia time (DWIT),…”
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Multicenter Study to Transplant Hepatitis C-Infected Kidneys (MYTHIC): An Open-Label Study of Combined Glecaprevir and Pibrentasvir to Treat Recipients of Transplanted Kidneys from Deceased Donors with Hepatitis C Virus Infection by Sise, Meghan E, Goldberg, David S, Kort, Jens J, Schaubel, Douglas E, Alloway, Rita R, Durand, Christine M, Fontana, Robert J, Brown, Jr, Robert S, Friedewald, John J, Prenner, Stacey, Landis, J Richard, Fernando, Melissa, Phillips, Caitlin C, Woodle, E Steve, Rike-Shields, Adele, Sherman, Kenneth E, Elias, Nahel, Williams, Winfred W, Gustafson, Jenna L, Desai, Niraj M, Barnaba, Brittany, Norman, Silas P, Doshi, Mona, Sultan, Samuel T, Aull, Meredith J, Levitsky, Josh, Belshe, Dianne S, Chung, Raymond T, Reese, Peter P

“…Single-center trials and retrospective case series have reported promising outcomes using kidneys from donors with hepatitis C virus (HCV) infection. However,…”
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The Proteasome Inhibitor Bortezomib Induces p53-Dependent Apoptosis in Activated B Cells by Ochoa, Trini A, Rossi, Amy, Woodle, E Steve, Hildeman, David, Allman, David

“…The proteasome inhibitor bortezomib (BTZ) is proposed to deplete activated B cells and plasma cells. However, a complete picture of the mechanisms underlying…”
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Early Corticosteroid Cessation vs Long-term Corticosteroid Therapy in Kidney Transplant Recipients: Long-term Outcomes of a Randomized Clinical Trial by Woodle, E Steve, Gill, John S, Clark, Stephanie, Stewart, Darren, Alloway, Rita, First, Roy

“…The complications of corticosteroids make the inclusion of these drugs in immunosuppressive protocols for kidney transplant patients undesirable. However,…”
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Bioequivalence between innovator and generic tacrolimus in liver and kidney transplant recipients: A randomized, crossover clinical trial by Alloway, Rita R, Vinks, Alexander A, Fukuda, Tsuyoshi, Mizuno, Tomoyuki, King, Eileen C, Zou, Yuanshu, Jiang, Wenlei, Woodle, E Steve, Tremblay, Simon, Klawitter, Jelena, Klawitter, Jost, Christians, Uwe

“…Although the generic drug approval process has a long-term successful track record, concerns remain for approval of narrow therapeutic index generic…”
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Targeting Plasma Cells with Proteasome Inhibitors: Principles from Primates by Woodle, E Steve, Tremblay, Simon, Driscoll, James

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Alemtuzumab Induction in Renal Transplantation by Hanaway, Michael J, Woodle, E. Steve, Mulgaonkar, Shamkant, Peddi, V. Ram, Kaufman, Dixon B, First, M. Roy, Croy, Richard, Holman, John

“…Renal-transplant recipients were given alemtuzumab induction therapy or conventional induction therapy as part of a program of early glucocorticoid withdrawal…”
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Bortezomib Provides Effective Therapy for Antibody-and Cell-Mediated Acute Rejection by EVERLY, Matthew J, EVERLY, Jason J, CARDI, Michael, WADIH, George, TEVAR, Amit, WOODIE, E. Steve, SUSSKIND, Brian, BRAILEY, Paul, ARENA, Lois J, ALLOWAY, Rita R, ROY-CHAUDHURY, Prabir, GOVIL, Amit, MOGILISHETTY, Gautham, RIKE, Adele H

“…Current antihumoral therapies in transplantation and autoimmune disease do not target the mature antibody-producing plasma cell. Bortezomib is a first in class…”
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A Prospective, Randomized, Double-Blind, Placebo-Controlled Multicenter Trial Comparing Early (7 Day) Corticosteroid Cessation Versus Long-Term, Low-Dose Corticosteroid Therapy by WOODLE, E. Steve, FIRST, M. Roy, PIRSCH, John, SHIHAB, Fuad, OSAMA GABER, A, VAN VELDHUISEN, Paul

“…To compare outcomes with early corticosteroid withdrawal (CSWD) and chronic low dose corticosteroid therapy (CCS). Final, 5-year results from the first…”
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Delayed Kinetics of IgG, but Not IgA, Antispike Antibodies in Transplant Recipients following SARS-CoV-2 Infection by Cravedi, Paolo, Ahearn, Patrick, Wang, Lin, Yalamarti, Tanuja, Hartzell, Susan, Azzi, Yorg, Menon, Madhav C, Jain, Aditya, Billah, Marzuq, Fernandez-Vina, Marcelo, Gebel, Howard M, Woodle, E Steve, Haddad, Natalie S, Morrison-Porter, Andrea, Lee, F Eun-Hyung, Sanz, Ignacio, Akalin, Enver, Girnita, Alin, Maltzman, Jonathan S

“…Kidney transplant recipients are at increased risk of severe outcomes during COVID-19. Antibodies against the virus are thought to offer protection, but a…”
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Proteasome inhibitor-based therapy for antibody-mediated rejection by Walsh, R Carlin, Alloway, Rita R, Girnita, Alin L, Woodle, E Steve

“…The development of donor-specific anti-human leukocyte antigen antibodies (DSAs) following renal transplantation significantly reduces long-term renal graft…”
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Assessment of tacrolimus intrapatient variability in stable adherent transplant recipients: Establishing baseline values by Leino, Abbie D., King, Eileen C., Jiang, Wenlei, Vinks, Alexander A., Klawitter, Jost, Christians, Uwe, Woodle, E. Steve, Alloway, Rita R., Rohan, Jennifer M.

“…The purpose of this study was to determine the intrapatient (within the same patient) variability of tacrolimus in adherent patients. Daily tacrolimus trough…”
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Long‐term outcomes in patients with obesity and renal disease after sleeve gastrectomy by Kassam, Al‐Faraaz, Mirza, Ahmad, Kim, Young, Hanseman, Dennis, Woodle, E. Steve, Quillin, Ralph C., Johnson, Bobby L., Govil, Amit, Cardi, Michael, Schauer, Daniel P., Smith, Eric P., Diwan, Tayyab S.

“…Morbid obesity is a barrier to kidney transplant in patients with end‐stage renal disease (ESRD). Laparoscopic sleeve gastrectomy (SG) is an increasingly…”
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Analysis of Cross-sectional and Longitudinal HLA and Anti-viral Responses After COVID Infection in Renal Allograft Recipients: Differences and Correlates by Girnita, Alin L., Wang, Lin, Colovai, Adriana I., Ahearn, Patrick, Azzi, Yorg, Menon, Madhav C., Fernandez-Vina, Marcelo, Gebel, Howard M., Steve Woodle, E., Cravedi, Paolo, Maltzman, Jonathan S., Akalin, Enver

“…Characterization of anti-HLA versus anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) immune globulin isotypes in organ transplant…”
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Proteasome Inhibitor-Based Primary Therapy for Antibody-Mediated Renal Allograft Rejection by WALSH, R. Carlin, EVERLY, Jason J, BRAILEY, Paul, RIKE, Adele H, AREND, Lois J, MOGILISHETTY, Gautham, GOVIL, Amit, ROY-CHAUDHURY, Prabir, ALLOWAY, Rita R, WOODLE, E. Steve

“…Rapid and complete elimination of donor-specific anti-human leukocyte antigen antibodies (DSA) during antibody-mediated rejection (AMR) is rarely achieved with…”
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