Search Results - "Woodcock, D.M."

Haematopoietic radioprotection by Cremophor EL: a polyethoxylated castor oil by Bertoncello, I, Kriegler, A B, Woodcock, D M, Williams, B, Barber, L, Nilsson, S K

“…The polyethoxylated castor oil, Cremophor EL (Cremophor) is approved for human use as a vehicle for oral and intravenous administration of water-insoluble…”
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Revised genomic consensus for the hypermethylated CpG island region of the human L1 transposon and integration sites of full length L1 elements from recombinant clones made using methylation-tolerant host strains by CROWTHER, P. J, DOHERTY, J. P, LINSENMEYER, M. E, WILLIAMSON, M. R, WOODCOCK, D. M

“…Efficient recovery of clones from the 5' end of the human L1 dispersed repetitive elements necessitates the use of deletion mcr- host strains since this region…”
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Quantitative evaluation of Escherichia coli host strains for tolerance to cytosine methylation in plasmid and phage recombinants by WOODCOCK, D. M, CROWTHER, P. J, DOHERTY, J, JEFFERSON, S, DECRUZ, E, NOYER-WEIDNER, M, SMITH, S. S, MICHAEL, M. Z, GRAHAM, M. W

“…Many strains of E. coli K12 restrict DNA containing cytosine methylation such as that present in plant and animal genomes. Such restriction can severely…”
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The majority of methylated deoxycytidines in human DNA are not in the CpG dinucleotide by Woodcock, D M, Crowther, P J, Diver, W P

“…The only natural postsynthetic modification known to occur in mammalian DNA is the methylation in the 5 position of deoxycytidines. Of the four 5'-CpN-3'…”
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A Sensitive RNase Protection Assay to Detect Transcripts from Potentially Functional Human Endogenous L1 Retrotransposons by Woodcock, D.M., Williamson, M.R., Doherty, J.P.

“…A high background of read-through transcripts from degenerate human L1 retrotransposons is present in almost all human cell types. This prevents the detection…”
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The human Pi class glutathione transferase sequence at 12q13-q14 is a reverse-transcribed pseudogene by Board, P G, Coggan, M, Woodcock, D M

“…A previous in situ hybridization study with a Pi class glutathione S-transferase cDNA probe revealed the presence of hybridizing sequences on the long arms of…”
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RgIB facilitated cloning of highly methylated eukaryotic DNA: the human L1 transposon, plant DNA, and DNA methylated in vitro with human DNA methyltransferase by Woodcock, D.M., Crowther, P.J., Diver, W.P., Graham, M., Bateman, C., Baker, D.J., Smith, S.S.

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Efficient construction of plant genomic libraries requires the use of mcr host strains and packaging mixes by Graham M.W, Doherty J.P, Woodcock D.M

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Modified-cytosine restriction-system-induced recombinant cloning artefacts in Escherichia coli by Williamson, M R, Doherty, J P, Woodcock, D M

“…We have tested whether, and to what extent, recombinant clones from DNA segments with 5-methylation of cytosines recovered in methylation-restrictive (mcr+)…”
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Methylation at dinucleotides other than CpG: implications for human maintenance methylation by Woodcock, D M, Crowther, P J, Jefferson, S, Diver, W P

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Effects of mcr restriction of methylated CpG islands of the L1 transposons during packaging and plating stages of mammalian genomic library construction by Doherty, J P, Graham, M W, Linsenmeyer, M E, Crowther, P J, Williamson, M, Woodcock, D M

“…The use of optimally methylation-tolerant mcrA- mcrB- strains has been shown to produce an over tenfold increase in the plating efficiencies of mammalian…”
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Aberrant double replication of segments of chromosomal DNA following DNA synthesis inhibition by cytosine arabinoside by Woodcock, D M, Cooper, I A

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Clonally derived cell lines with altered DNA methylation as models for error correction and mutation in tumours by Diver, W P, Woodcock, D M

“…We have investigated the relative importance of DNA methylation-directed repair of replication errors to the production of mutation/gene rearrangements in…”
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Delayed DNA methylation is an integral feature of DNA replication in mammalian cells by Woodcock, D M, Simmons, D L, Crowther, P J, Cooper, I A, Trainor, K J, Morley, A A

“…In the majority of sites of methylation in the DNA of mammalian cells, the symmetry of methylation is restored within a few minutes of the passage of a…”
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Levels and stability of DNA methylation in random surviving cell clones derived from a Chinese hamster cell line after prolonged treatment with 5-aza-2'-deoxycytidine by Woodcock, D M, Crowther, P J, Simmons, D L, Cooper, I A

“…SCC30 cells (derived from a single cell from the Chinese hamster ovary CHO-K1 cell line, selected on the basis of a stable chromosome complement) were used to…”
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Differential variations in the DNA of Drosophila melanogaster during development by Woodcock, D M, Sibatani, A

“…Evidence is presented that during development there is active regulation of the information content of the genome of Drosophila melanogaster. This regulation…”
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Sequence specificity of cytosine methylation in the DNA of the Chinese hamster ovary (CHO-K1) cell line by Woodcock, D M, Crowther, P J, Simmons, D L, Cooper, I A

“…We have determined the DNA renaturation kinetics for those DNA sequences of the Chinese hamster ovary (CHO-K1) cells in which enzymatic cytosine methylation…”
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An explanation for the S-phase specificity of the cytotoxicity of protein synthesis inhibitors by Woodcock, D M, Adams, J K, Cooper, I A

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